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192
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ShareScore release 0.9.0
Dataset results
192 results for “glycosylation”
Disruption of the epigenetic regulator BAP1 drives chromatin remodeling leading to the emergence of cells with breast cancer stem cell properties and aberrant glycosylation [ChiPseq_2D]
GEO Series GSE271683. Homo sapiens. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Glycosylation-dependent modulation of the IL-2 signaling axis determines Th17 differentiation and IL-10 production
GEO Series GSE129028. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
To understand how glycosylation on human B cells is regulated during differentiation and activation
GEO Series GSE31932. Homo sapiens. 8 samples. Type: Expression profiling by array.
Glycosylation-related gene expression in gastrointestinal cell line HT29 in response to infection by Campylobacter jejuni
GEO Series GSE107563. Homo sapiens. 4 samples. Type: Expression profiling by array.
Microarray analysis of RNA of TCR transgenic CD8 T cells to assess the role of protein glycosylation in the decision between deletion vs. anergy in immune tolerance
GEO Series GSE31988. Mus musculus. 11 samples. Type: Expression profiling by array.
SARS-CoV-2 virus seems to induce O-glycosylation and other metabolic dysfunctions which might predispose new-onset diabetes
<p>COVID-2019 pandemic has caused huge damage to human health, and some individuals are more prone to severe manifestations, such as type-2 diabetic patients. The correlation between diabetes and severe manifestations have been under investigation, and molecular findings may highlight some pathophysiological pathways. The present study aimed to identify plasma metabolites in patients affected by type-2 diabetes and COVID-19, concomitantly, using an untargeted metabolomic approach. We employed high-resolution mass spectrometry analysis to annotate 10 metabolites, with N-acetyl-D-glucosamine among them; it is involved with O-glycosylation, which is enhanced in diabetic conditions. SARS-CoV-2 Spike proteins depend on glycosylation, what seems to be overstimulated upon infection. Interestingly, N-acetyl-D-glucosamine was found in part of the non-diabetic COVID-19 patients, indicating that SARS-CoV-2 might induce new-onset diabetes through glycosylation. Besides, the identified biomarkers seem to be all interconnected and represent a global perception of metabolic alterations in a Diabetic-COVID-19 scenario, highlighting new targets for further pharmacological interventions.</p>
To identify specific glycosylated structures on brain endothelial cells that mediate rolling, adhesion, and diapedesis of leukocytes in the brain
GEO Series GSE29932. Homo sapiens. 10 samples. Type: Expression profiling by array.
The role of glycans and glycosylation in cell-type specific effects on viral infectivity
GEO Series GSE29924. Homo sapiens. 4 samples. Type: Expression profiling by array.
Microarray of RNA of TCR transgenic CD8 T cells to assess the role of protein glycosylation in the decision between deletion vs. anergy in immune tolerance
GEO Series GSE29935. Mus musculus. 9 samples. Type: Expression profiling by array.
PMI-controlled mannose metabolism and glycosylation determines tissue tolerance and virus fitness
GEO Series GSE255332. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Altered Innate Immunity Confers Staphylococcus aureus Resistance in O-glycosylation Deficient Caenorhabditis elegans bus Mutants
GEO Series GSE143664. Caenorhabditis elegans. 15 samples. Type: Expression profiling by array.
Movies used in manuscript "Cellular glycosaminoglycans and viral protein glycosylation regulate diffusion and entry of herpesvirus at cell surface
<p>Movies S1. Timelapses of HSV-1 (KOS strain) diffusing at the surface of (A) wt CHO-K1 cells expressing both herapan sulfate (HS) and chondroitin sulfate (CS), (B) wt CHO cells treated with chondroitinase ABC, lacking chondroitin sulfate (CHO-ΔCS), (C) pgsD-677 lacking HS (CHO-ΔHS). (D) Timelapse of HSV-1 (KOS strain) on wt HaCat cells. (E) Timelapse of the mutant HSV-1 (KOS-gCΔmuc) on wt HaCat cells. The scale bar represents 10 μm. Using Fiji, all movies were corrected for uneven background using the same procedure with a rolling ball of 50 and the noise was despeckled. The LUT thresholds were set to be 10 as minimum and 50 as maximum for all videos. Finally, the movies were then saved as .avi using an acceleration of 50 frame per second. (F) The virus trajectories reconstructed using Trackmate are shown on the movie corresponding to A for wt CHO. The colors of the trajectory are arbitrary.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.