Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
347
datasets available to search
ShareScore release 0.9.0
Dataset results
347 results for “hypothermia”
Predictors and Outcomes of Intraoperative Hypothermia in Patients Undergoing Knee Arthroplasty
ClinicalTrials.gov study NCT04575246. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Evaluation of Core Body Temperature When Using Forced Air Warming or an Active Blanket to Prevent Perioperative Hypothermia
ClinicalTrials.gov study NCT02079311. IPD Sharing: Not stated. Countries: 3. Publications: 0.
Data from: Is embryonic hypothermia tolerance common in birds?
Open the record for dataset details and reuse information.
Data from: Nocturnal hypothermia impairs flight ability in birds: a cost of being cool
Open the record for dataset details and reuse information.
Identification of novel diagnostic markers for fatal hypothermia by body temperature-dependent gene expression analysis in rats
GEO Series GSE109148. Rattus norvegicus. 12 samples. Type: Expression profiling by high throughput sequencing.
Development of gene expression signatures for BV-2 microglia activation in the background of mild hypothermia
GEO Series GSE171696. Mus musculus. 12 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
SMYD5 is a regulator of the mild hypothermia response [RNA-Seq]
GEO Series GSE234688. Mus musculus. 31 samples. Type: Expression profiling by high throughput sequencing.
SMYD5 is a regulator of the mild hypothermia response [CRISPR-Cas9 screen]
GEO Series GSE234698. Homo sapiens. 12 samples. Type: Other.
SMYD5 is a regulator of the mild hypothermia response
GEO Series GSE234699. Homo sapiens; Mus musculus. 127 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Activation of GFRAL+ Neurons Induces Hypothermia and Glucoregulatory Responses Associated with Nausea and Torpor
GEO Series GSE255540. Mus musculus. 50 samples. Type: Expression profiling by high throughput sequencing.
Effects of hypothermia on gene expression in zebrafish gills
GEO Series GSE7853. Danio rerio. 6 samples. Type: Expression profiling by array.
Data from: Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia
Objective: Morphine is a commonly used drug in encephalopathic neonates treated with therapeutic hypothermia after perinatal asphyxia. Pharmacokinetics and optimal dosing of morphine in this population are largely unknown. The objective of this study was to describe pharmacokinetics of morphine and its metabolites morphine-3-glucuronide and morphine-6-glucuronide in encephalopathic neonates treated with therapeutic hypothermia and to develop pharmacokinetics based dosing guidelines for this population. Study design: Term and near-term encephalopathic neonates treated with therapeutic hypothermia and receiving morphine were included in two multicenter cohort studies between 2008-2010 (SHIVER) and 2010-2014 (PharmaCool). Data were collected during hypothermia and rewarming, including blood samples for quantification of morphine and its metabolites. Parental informed consent was obtained for all participants. Results: 244 patients (GA mean (sd) 39.8 (1.6) weeks, BW mean (sd) 3,428 (613) g, male 61.5%) were included. Morphine clearance was reduced under hypothermia (33.5°C) by 6.89%/°C (95% CI 5.37%/°C – 8.41%/°C, p<0.001) and metabolite clearance by 4.91%/°C (95% CI 3.53%/°C – 6.22%/°C, p<0.001) compared to normothermia (36.5°C). Simulations showed that a loading dose of 50 μg/kg followed by continuous infusion of 5 μg/kg/h resulted in morphine plasma concentrations in the desired range (between 10 and 40 μg/L) during hypothermia. Conclusions: Clearance of morphine and its metabolites in neonates is affected by therapeutic hypothermia. The regimen suggested by the simulations will be sufficient in the majority of patients. However, due to the large interpatient variability a higher dose might be necessary in individual patients to achieve the desired effect.
Retrograde Versus Antegrade Perfusion in Low-Moderate Hypothermia for Aortic Arch Surgery
ClinicalTrials.gov study NCT06986967. IPD Sharing: YES. Countries: 1. Publications: 0.
MRI of Neonate With HIE Before and During the Moderate Hypothermia
ClinicalTrials.gov study NCT03079492. IPD Sharing: NO. Countries: 1. Publications: 0.
Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia
ClinicalTrials.gov study NCT02621944. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Randomised Controlled Trial on Using Active Warming to Prevent Newborn Hypothermia After Caesarean Delivery
ClinicalTrials.gov study NCT06532266. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Limitation of Ischemic Injury of a Kidney Stored in Machine Perfusion in Hypothermia - Evaluation of the Impact on Kidney Allograft Function
ClinicalTrials.gov study NCT01731457. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Beneficial Effect of Hypothermia Plus Hemicraniectomy Compared With Hemicraniectomy
ClinicalTrials.gov study NCT04825418. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluation of a Patient Warming Concept Following the German S3 Guideline for Prevention of Intraoperative Hypothermia
ClinicalTrials.gov study NCT02206997. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Hypothermia and Circulatory Arrest During Surgery on the Ascending Aorta: A Comparison Between Two Cooling Methods
ClinicalTrials.gov study NCT01306734. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.