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1,624 results for “steroids”
Fig. 6 in Five undescribed steroids from Talaromyces stipitatus and their cytotoxic activities against hepatoma cell lines
Fig. 6. Cell cycle phases of Hep3B cells. Cells were treated for 24 h with (a) 0.2% DMSO; (b) compound 4 at 5 μM; (c) compound 8 at 5 μM; and (d) sorafenib at 3.5 μM. After labeling with PI staining solution, the cells were subjected to flow cytometry. Diagrams of the cell cycle phases are shown ***p <0.001 compared with the control group.
Fig. 7 in Five undescribed steroids from Talaromyces stipitatus and their cytotoxic activities against hepatoma cell lines
Fig. 7. Apoptosis in Hep3B cells induced by compounds 4 and 8. Cells were treated with (a, e) 0.1% DMSO (control); (b, f) compound 4 at 5 μM; (c, g) compound 8 at 5 μM, and (d, h) sorafenib at 3.5 μM for a period of 24 and 48 h. The four subpopulations indicate Q4, viable; Q3, early apoptotic; Q2, late apoptotic; and Q1, necrotic. Quantification of the percentage of cells in each quadrant is shown. ***p <0.001, ****p <0.0001 compared with the control group.
Fig. 2 in Transcriptome analysis of Paris polyphylla var. yunnanensis illuminates the biosynthesis and accumulation of steroidal saponins in rhizomes and leaves
Fig. 2. Genes involved in Paris saponin biosynthesis. (a) Genes participated in the MVA and MEP pathways. (b) Genes participated in the downstream of saponin backbone biosynthesis.
Fig. 4 in Transcriptome analysis of Paris polyphylla var. yunnanensis illuminates the biosynthesis and accumulation of steroidal saponins in rhizomes and leaves
Fig. 4. An overview of DEG expression patterns and GO enrichments. (a) Heatmap of expression values for all DEGs. (b) GO enrichments of DEGs, with displaying the top fifteen subcategories for each category.
Fig. 7 in Transcriptome analysis of Paris polyphylla var. yunnanensis illuminates the biosynthesis and accumulation of steroidal saponins in rhizomes and leaves
Fig. 7. QRT-PCR validation of RNA-Seq data. Expression profiles of eight selected genes were determined by transcriptome and qRT-PCR data. The left vertical axis represents the relative expression of the gene based on qRT-PCR. The right vertical axis represents the expression level of the gene based on transcriptome sequencing. The asterisk above the bar chart denotes statistical significance based on the qRT-PCR data (* denotes P value <0.05, ** denotes P value <0.01, ns denotes P value> 0.05).
Fig. 1 in Transcriptome analysis of Paris polyphylla var. yunnanensis illuminates the biosynthesis and accumulation of steroidal saponins in rhizomes and leaves
Fig. 1. The bioactive compound content and transcriptome characters. (a) Total content of three typical types of Paris saponins in leaves and rhizomes during the vegetative and fruiting stages. VL: leaves at vegetative stage, VR: rhizomes at vegetative stage, FL: leaves at fruiting stage, and FR: rhizomes at fruiting stage. (b) Proportion of three types of Paris saponins in leaves and rhizomes. (c) Distribution of the expressed unigenes in tissues during the two stages (log2 (TPMþ1)> 0). (d) Boxplot of unigene expression profiles.
Fig. 3 in Transcriptome analysis of Paris polyphylla var. yunnanensis illuminates the biosynthesis and accumulation of steroidal saponins in rhizomes and leaves
Fig. 3. DEG statistics. (a) Venn diagram of DEGs from the four paired comparisons. (b) The number of up-down regulated DEGs of the four paired comparisons.
Fig. 5 in Previously undescribed pyridyl-steroidal glycoalkaloids and 23S,26R-hydroxylated spirostanoid saponin from the fruits of Solanum violaceum ortega and their bioactivities
Fig. 5. Apoptosis induced by 9 in MCF-7 cells. [Q3: The early stage of apoptosis (FITC positive, PI negative) Q2: The late stage of apoptosis (FITC positive, PI positive) Q4: The live cells (FITC negative, PI negative)].
Fig. 3. X in Structurally diverse steroids with nitric oxide inhibitory activities from Aglaia lawii leaves
Fig. 3. X-ray structure of 1 (A) and the assembly of molecules of 1 in the crystals (hydrogen-bonds are shown as dashed lines) (B).
Efficacy of Steroid Versus Steroid Plus Cyclophosphamide for Severe Henoch-Schoenlein Purpura
ClinicalTrials.gov study NCT00190229. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy
ClinicalTrials.gov study NCT04182997. IPD Sharing: NO. Countries: 1. Publications: 14.
Topical Steroids Alone or Associated With Methotrexate in Bullous Pemphigoid
ClinicalTrials.gov study NCT02313870. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Rituximab Therapy for Steroid-Refractory Chronic Graft Versus Host Disease
ClinicalTrials.gov study NCT00136396. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Comparing the Therapeutic Effects of Using Ruxolitinib and Steroids Concurrently to Steroids Alone as Initial Treatment In Patients Diagnosed With Chronic Graft-versus-host Disease at a Grade of Moder
ClinicalTrials.gov study NCT06756061. IPD Sharing: NO. Countries: 1. Publications: 28.
Steroid Sparing Effect of Nasal Corticosteroid In Asthma And Rhinitis
ClinicalTrials.gov study NCT00903227. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Efficacy of Steroid Injection in Patients With Bifid Median Nerve Diagnosed Carpal Tunnel Syndrome
ClinicalTrials.gov study NCT06599086. IPD Sharing: NO. Countries: 1. Publications: 3.
Impact of a Booster Course of Antenatal Steroids on Neonatal Outcome in Patients With Premature Rupture of the Membranes
ClinicalTrials.gov study NCT02469519. IPD Sharing: NO. Countries: 1. Publications: 1.
Stem Cells vs. Steroids for Discogenic Back Pain
ClinicalTrials.gov study NCT04735185. IPD Sharing: YES. Countries: 1. Publications: 2.
A Study to Determine the Effects of PF-04965842 on the Pharmacokinetics of Oral Contraceptive Steroids in Healthy Female Subjects
ClinicalTrials.gov study NCT03662516. IPD Sharing: NO. Countries: 1. Publications: 1.
Taper Or Abrupt Steroid Stop: TOASSTtrial
ClinicalTrials.gov study NCT03153527. IPD Sharing: NO. Countries: 2. Publications: 1.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.