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15,733 results for “article”
Dataset of the Distress Screening Scale for the article: Emotional distress, coping, and social support: A network analysis of risk and resources in persons with cancer
<p>Dataset of the Distress Screening System comprises 52 items that relate to six psycho-social domains of human functioning: depression, anxiety, social support, coping efficacy, satisfaction with care, and functional status</p>
dateset relate to article (submitted) Evaluation of mitochondrial dysfunction and idebenone responsiveness in fibroblasts from Leber's Hereditary Optic Neuropathy (LHON) subjects.
<p>raw data related to the article at title</p>
Interview Guide for the article: Examining Online International Health Professions Education: A Mixed Methods Review of Barriers, Facilitators, and Early Outcomes
<p>This interview guide was used to conduct the 17 interviews upon which the qualitative portion of the research was built.</p>
Supplementary material for the article entitled "Socioeconomic Analysis of the Proposed Opening of the Brazilian energy Market Through the Combination of Forecast Method with the Optimized Tariff Model"
<p>This supplementary material includes the input data used for the simulations conducted in the article.</p>
Dataset A of article "A machine learning approach for classifying Mediterranean obsidian of archaeometric interest by SEM investigation"
<p>Dataset A used for the manuscript titled "A machine learning approach for classifying Mediterranean obsidian of archaeometric interest by SEM investigation".</p><p>This dataset is a txt file, tab separated, encoded in UTF-8, with newline line terminator.</p><p>A compressed zip file is also provided, which, expanded, will create a directory containing 890 files. The files come in couples with the same name and two different extensions: spc (with SEM-EDS spectroscopy data) and tif (with SEM-BSE images). The SEM-EDS data refers to the same sample area shown in the SEM-BSE image going under the same name.</p>
Result data for article "Clade-wise alignment integration improves co-evolutionary signals for protein-protein interaction prediction"
<p>This dataset contains all the necessary data to reproduce figures in the paper [ "Clade-wise alignment integration improves co-evolutionary signals for protein-protein interaction prediction"](https://www.biorxiv.org/content/10.1101/2023.07.28.550005v1).</p> <p>More details can be found at: <a href="https://github.com/TaoDFang/PPI_Prediction_byCoevolution">https://github.com/TaoDFang/PPI_Prediction_byCoevolution</a></p>
Data from "Seedling establishment in a deciduous and an evergreen oak under simulated climate change" article
<p>Field-collected data that support the findings of the study "Lázaro-González, A., Tamulaityté, G., Castro, J., Uscola, M., Leverkus, AB. 2023. Seedling establishment in a deciduous and an evergreen oak under simulated climate change. <i>Forest Ecology and Management, </i>550: 121498.</p>
Data of the article "Emergence of bidirectional cell laning from collective contact guidance"
<p>Data (datasets, images and video) that support the findings of the corresponding article (Lacroix et al., Emergence of bidirectional cell laning from collective contact guidance), and that are not in the Supplementary Material file.</p>
Dataset for journal article "Understanding the timeliness of automated data feeds is important for determining their usability for large-scale surveillance of healthcare-associated infections"
<p>This dataset was used for the journal article "Understanding the timeliness of automated data feeds is important for determining their usability for large-scale surveillance of healthcare-associated infections".</p> <p>For a selection of "activity dates", it contains the number of records available centrally at UKHSA on each day after the specified activity date, from a selection of data feeds that could potentially be used for national surveillance of healthcare-associated infections in England.</p> <p>The associated R code is available from https://github.com/oxfordmmm/ukhsa-datafeeds-timeliness-anon</p>
The Effect of the Use of Jigsaw Technique on Nursing Students' Critical Article Reviews and Students' Opinions on the Technique- Quasi-Experimental Study
ClinicalTrials.gov study NCT06339502. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Trial of Safety/Efficacy of Test Article in Patients With Interdigital T. Pedis
ClinicalTrials.gov study NCT04315051. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effect of Jigsaw Technique Used in Critical Article Review on Critical Thinking Disposition and Communication Skills
ClinicalTrials.gov study NCT05864781. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Metadata collected from 500 articles in the field of ecology and evolution
Open the record for dataset details and reuse information.
Dataset for the JGR-SE article: Seismic evidence for water transportation in the forearc off Northern Japan
<p>The obtained 3-D P-wave velocity model.</p>
Dataset related to the article "MiRNA profiling revealed enhanced susceptibility to oxidative stress of endothelial cells from bicuspid aortic valve"
<p>This record contains raw data related to the article "MiRNA profiling revealed enhanced susceptibility to oxidative stress of endothelial cells from bicuspid aortic valve"</p> <p> </p> <p><strong>Abstract</strong></p> <p>Aims</p> <p>Calcific <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/aortic-valve-stenosis">aortic valve stenosis</a> (CAVS) is the most frequent manifestation of <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/aortic-valve-disease">aortic valve disease</a> and the third leading cause of cardiovascular disease in the Western countries associated with significant morbidity and mortality. An active biological progression involving inflammation and <a href="https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/alpha-oxidation">oxidation</a> leading to valve endothelial damage is considered a hallmark of the early stages of valve degeneration. However, tricuspid (TAV) and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/premolar">bicuspid</a> (BAV) <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/aortic-valve">aortic valve</a> deterioration are considered to differ only by shear stress. We hypothesized that <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/endothelial-cell">endothelial cells</a> (EC) derived from BAV and TAV patients have different <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/microrna">miRNA</a> expression patterns and thus distinct pathways could lead to endothelial damage in BAV than TAV patients.</p> <p>Methods and results</p> <p>We isolated ECs from patients with bicuspid or tricuspid aortic valve, which underwent surgery due to CAVS. MiRNA expression profile by PCR revealed eight upregulated <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/microrna">miRNAs</a> between BAV and TAV ECs. Functional analysis identified that BAV ECs presented altered cellular response to <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/oxidative-stress">oxidative stress</a> and DNA damage stimulus <em>via</em> <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/protein-p53">p53</a> and alteration in the intrinsic apoptotic <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/signal-transduction">signaling pathway</a>. <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/gpx3">GPX3</a> and SRXN1 <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/messenger-rna">mRNA</a> were express at lower levels in BAV compared to TAV ECs, leading to an increment of <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/double-stranded-dna">DNA double-strand</a> breaks. BAV ECs had a sustained <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/programmed-cell-death">apoptosis</a> activation when compared to TAV ECs. This difference was exacerbated by oxidative stress stimulus leading to a reduced survival rate but completely reverted by miR-328-3p inhibition.</p> <p>Conclusion</p> <p>The present data showed molecular differences in oxidative stress susceptibility, DNA damage magnitude, and apoptosis induction between ECs derived from BAV and TAV patients.</p>
Dataset related to the article "Aortic Valve Sclerosis Adds to Prediction of Short-Term Mortality in Patients with Documented Coronary Atherosclerosis"
<p>This record contains raw data related to the article "Aortic Valve Sclerosis Adds to Prediction of Short-Term Mortality in Patients with Documented Coronary Atherosclerosis".</p> <p> </p> <p><strong>Abstract</strong></p> <p>Aims: Aortic valve sclerosis (AVSc), a non-uniform thickening of leaflets with an unrestricted opening, is characterized by inflammation, lipoprotein deposition, and matrix degradation. In the general population, AVSc predicts long-term cardiovascular mortality (+50%) even after adjustment for vascular risk factors and clinical atherosclerosis. We have hypothesized that AVSc is a risk-multiplier able to predict even short-term mortality. To address this issue, we retrospectively analyzed 90-day mortality of all patients who underwent isolated coronary artery bypass grafting (CABG) at Centro Cardiologico Monzino over a ten-year period (2006–2016). Methods: We analyzed 2246 patients and 90-day all-cause mortality was 1.5% (31 deaths). We selected only patients deceased from cardiac causes (n = 29) and compared to alive patients (n = 2215). A cardiologist classified the aortic valve as no-AVSc (n = 1352) or AVSc (n = 892). Cox linear regression and integrated discrimination improvement (IDI) analyses were used to evaluate AVSc in predicting 90-day mortality. Results: AVSc 90-day survival (97.6%) was lower than in no-AVSc (99.4%; p < 0.0001) with a hazard ratio (HR) of 4.0 (95%CI: 1.78, 9.05; p < 0.0001). The HR for AVSc, adjusted for propensity score, was 2.7 (95%CI: 1.17, 6.23; p = 0.02) and IDI statistics confirmed that AVSc significantly adds (p < 0.001) to the identification of high-risk patients than EuroSCORE II alone. Conclusion: Our data supports the hypothesis that a risk stratification strategy based on AVSc, added to ESII, may allow better recognition of patients at high-risk of short-term mortality after isolated surgical myocardial revascularization. Results from this study warrant further confirmation.</p>
Dataset related to the article "Endothelial Dysfunction in Patients with Severe Mitral Regurgitation"
<p>This record contains raw data related to the article "Endothelial Dysfunction in Patients with Severe Mitral Regurgitation"</p> <p> </p> <p><strong>Abstract</strong></p> <p>Mitral valve prolapse (MVP) is the most common cause of severe mitral regurgitation. It has been reported that MVP patients—candidates for mitral valve repair (MVRep)—showed an alteration in the antioxidant defense systems as well as in the L-arginine metabolic pathway. In this study, we investigate if oxidative stress and endothelial dysfunction are an MVP consequence or driving factors. Forty-five patients undergoing MVRep were evaluated before and 6 months post surgery and compared to 29 controls. Oxidized (GSSG) and reduced (GSH) forms of glutathione, and L-arginine metabolic pathway were analyzed using liquid chromatography-tandem mass spectrometry methods while osteoprotegerin (OPG) through the ELISA kit and circulating endothelial microparticles (EMP) by flow cytometry. Six-month post surgery, in MVP patients, the GSSG/GSH ratio decreased while symmetric and asymmetric dimethylarginines levels remained comparable to the baseline. Conversely, OPG levels significantly increased when compared to their baseline. Finally, pre-MVRep EMP levels were significantly higher in patients than in controls and did not change post surgery. Overall, these results highlight that MVRep completely restores the increased oxidative stress levels, as evidenced in MVP patients. Conversely, no amelioration of endothelial dysfunction was evidenced after surgery. Thus, therapies aimed to restore a proper endothelial function before and after surgical repair could benefit MVP patients.</p>
Dataset related to the article "Impact of Oxidative Stress and Protein S-Glutathionylation in Aortic Valve Sclerosis Patients with Overt Atherosclerosis"
<p>This record contains raw data related to the article "Impact of Oxidative Stress and Protein S-Glutathionylation in Aortic Valve Sclerosis Patients with Overt Atherosclerosis"</p> <p> </p> <p><strong>Abstract</strong></p> <p>Aortic valve sclerosis (AVSc) is characterized by non-uniform thickening of the leaflets without hemodynamic changes. Endothelial dysfunction, also caused by dysregulation of glutathione homeostasis expressed as ratio between its reduced (GSH) and its oxidised form (GSSG), could represent one of the pathogenic triggers of AVSc. We prospectively enrolled 58 patients with overt atherosclerosis and requiring coronary artery bypass grafting (CABG). The incidence of AVSc in the studied population was 50%. The two groups (No-AVSc and AVSc) had similar clinical characteristics. Pre-operatively, AVSc group showed significantly lower GSH/GSSG ratio than No-AVSc group (<em>p = </em>0.02). Asymmetric dimethylarginine (ADMA) concentration was significantly higher in AVSc patients compared to No-AVSc patients (<em>p < </em>0.0001). Explanted sclerotic aortic valves presented a significantly increased protein glutathionylation (Pr-SSG) than No-AVSc ones (<em>p = </em>0.01). In vitro, inhibition of glutathione reductase caused β-actin glutathionylation, activation of histone 2AX, upregulation of α2 smooth muscle actin (<em>ACTA2</em>), downregulation of platelet and endothelial cell adhesion molecule 1 (<em>PECAM1</em>) and cadherin 5 (<em>CDH5</em>). In this study, we showed for the first time that the dysregulation of glutathione homeostasis is associated with AVSc. We found that Pr-SSG is increased in AVSc leaflets and it could lead to EndMT via DNA damage. Further studies are warranted to elucidate the causal role of Pr-SSG in aortic valve degeneration.</p>
HER2 data used in the article entitled "MSclassifier: Median-Supplement model-based Classification tool for automated knowledge discovery"
<p>This repository contains HER2 training and test sets used for evaluating MSclassifier and other packages in the software article entitled "MSclassifier: median-supplement model-based classification tool for automated knowledge discovery." The training set is comprised of 100 instances and 74 attributes while the test set is comprised of 62 instances and 74 attributes. The training samples were used to obtain results from a 10-fold cross-validation testing of how MSclassifier and other packages accurately predicted HER2-receptor status phenotypes in breast cancer in the article. The data used in the software article was obtained from the supplementary data of "Adabor ES, Acquaah-Mensah GK, Machine learning approaches to decipher hormone and HER2 receptor status phenotypes in breast cancer, Briefings in Bioinformatics 2019; 20 (2): 504–514, https://doi.org/10.1093/bib/bbx138" by permission of Oxford University Press. Here, it is reproduced by permission of Oxford University Press.</p> <p> </p>
Supplementary Materials for Article "Toward a Bibliometric History of Romantic Studies"
<p>Data used in the article "Toward a Bibliometric History of Romantic Studies".</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.