Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
5,016
datasets available to search
ShareScore release 0.9.0
Dataset results
5,016 results for “THERAPEUTICS”
Sequential redox vulnerabilities with therapeutic potential during the acquisition of drug resistance in BRAFV600E lung adenocarcinoma
GEO Series GSE271247. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
NSUN6 is a prognostic indicator and therapeutic target in esophageal squamous cell carcinoma
GEO Series GSE242287. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Genetic Screen in a Pre-Clinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities
GEO Series GSE228213. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases [breast cancer validation cohort]
GEO Series GSE123087. Homo sapiens. 38 samples. Type: Expression profiling by array.
Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia
GEO Series GSE46554. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genetic surexpression of human BIN1 as a therapeutic approach in a murine model of X-linked myotubular myopathy (Mtm1-/y)
GEO Series GSE160081. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
SPP1 represents a therapeutic target that promotes the progression of esophageal squamous cell carcinoma by driving M2 macrophage infiltration
GEO Series GSE256360. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Hi-C profiling in tissues reveals 3D chromatin-regulated breast tumor heterogeneity informing a looping-mediated therapeutic avenue
GEO Series GSE261230. Homo sapiens. 12 samples. Type: Other.
Oncogenic MAPK signalling induces epithelial cell state change and therapeutic resistance in vivo [scRNA-Seq]
GEO Series GSE307774. Mus musculus. 29 samples. Type: Expression profiling by high throughput sequencing.
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: high-resolution mapping of BRD4 binding sites in the KSHV genome
GEO Series GSE103395. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Targeted release of a bispecific fusion protein SIRPα/Siglec-10 by oncolytic adenovirus reinvigorates tumor associated macrophages to improve therapeutic outcomes in solid tumors
GEO Series GSE275905. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
MLL3 loss drives metastasis and therapeutic resistance by promoting a hybrid EMT state [RNA-seq]
GEO Series GSE171444. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia
GEO Series GSE101480. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Gene-metabolite network analysis revealed tissue specific accumulation of therapeutic metabolites in Mallotus japonicus
GEO Series GSE179338. Mallotus japonicus. 7 samples. Type: Expression profiling by high throughput sequencing.
DNA methylation as a therapeutic target in RB1 deficient and neuroendocrine prostate cancer and rational co-targeting with B7-H3 [22Rv1sgRB1]
GEO Series GSE216713. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
ACSS2-Mediated Lysine Crotonylation Attenuates Senescence and Enhances the Therapeutic Efficacy of Adipose-derived Stem Cells in Inflammatory Bowel Disease [RNA-Seq]
GEO Series GSE315663. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas [RNA-Seq]
GEO Series GSE117446. Homo sapiens. 96 samples. Type: Expression profiling by high throughput sequencing; Other.
Elucidation of focal adhesion kinase as a modulator of migration and invasion and as a potential therapeutic target in chronic lymphocytic leukemia (RNA-Seq I)
GEO Series GSE198454. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Spatial distribution and chromatin accessibility determine the therapeutic capacity of microglial subsets during neurodegeneration [scRNAseq1_LPS_ABX]
GEO Series GSE296026. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
The Androgen Receptor: A Therapeutic Target In Desmoplastic Small Round Cell Sarcoma
GEO Series GSE178406. Homo sapiens. 32 samples. Type: Protein profiling by protein array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.