Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
13,621
datasets available to search
ShareScore release 0.9.0
Dataset results
13,621 results for “Biologics”
Replication package for: Stunting and wasting in a growing economy: biological living standards in Portugal during the twentieth century (updated)
<p>The replication materials contain a README file, STATA as well as .csv datasets, and do-files. This replication package for Cermeño et al. (2023) constructs the entire analysis from the data sources described in the published paper, using STATA. The replicator should expect the code to run for less than 10 minutes.</p> <p>Cermeño, A. L., Palma, N., and Pistola, R. (2023). Stunting and wasting in a growing economy: biological living standards in Portugal during the twentieth century. <em><strong>Economics & Human Biology</strong></em>, vol. 51: 101267</p>
Figure 2 in Biology of jungle perch, Kuhlia rupestris, identification of threats and knowledge gaps to improve local and global management
Figure 2. – Diet of K. rupestris in northern Queensland (Pusey et al., 2004).
Data from: A synthetic biology and green bioprocess approach to recreate agarwood sesquiterpenoid mixtures
<p>Certain endangered Thymelaeaceous trees are major sources of the fragrant and highly valued resinous agarwood, comprised of hundreds of oxygenated sesquiterpenoids (STPs). Despite growing pressure on natural agarwood sources, the chemical complexity of STPs severely limits synthetic production. Here, we catalogued the chemical diversity in 58 agarwood samples by two-dimensional gas chromatography–mass spectrometry and partially recreated complex STP mixtures through synthetic biology. We improved STP yields in the unicellular alga <em>Chlamydomonas reinhardtii </em>by combinatorial engineering to biosynthesise nine macrocyclic STP backbones found in agarwood. A bioprocess following green-chemistry principles was developed that exploits 'milking' of STPs without cell lysis, solvent–solvent STP extraction, solvent–STP nanofiltration, and bulk STP oxy-functionalisation to obtain terpene mixtures like those of agarwood. This process occurs with total solvent recycling and enables continuous production. Our synthetic-biology approach offers a sustainable alternative to harvesting agarwood trees to obtain mixtures of complex, fragrant, oxygenated STPs.</p>
Habitat quality and biological community responses to innovative hydropower plant installations at transverse in-stream structures
<ol> <li>Ecological assessments of the effects of hydropower plants (HPPs) are often limited to aspects of entrainment, mortality, injuries, and passage of fish, whereas the effects on riverine habitats and biological communities in proximity to these structures are hardly documented.</li> <li>In this study, aquatic communities comprising fish, macroinvertebrates, macrophytes, and periphyton as well as physical and hydromorphological parameters were investigated in upstream and downstream river sections at five transverse structures at different seasons before and after the installation of an innovative HPP.</li> <li>At all study sites, significant differences in the aquatic community composition between the assessed upstream and downstream sections were found after HPP construction, indicating distinct serial discontinuity.</li> <li>Raising the damming target at the sites Großweil and Au deteriorated the habitat conditions in the upstream area close to the weir and presumably influenced in particular the macroinvertebrate community, where a significant decrease in the density of rheophilic mayfly, stonefly, and caddisfly larvae was observed after HPP construction.</li> <li> <em>Synthesis and applications</em>: The installation of different types of innovative HPPs has not improved the habitat conditions for rheophilic species, contrary to the promises raised by the developers of these concepts. Conversely, retrofitting existing weirs accompanied by further damming even significantly increased the effects of serial discontinuity and deteriorated the habitat conditions for rheophilic species in upstream sections. As evident from the findings of this study, habitat and biological community effects resulting from serial discontinuity should become better integrated into ecological assessments of HPP developments.</li> </ol>
Supporting information for "Automated ChIPmentation procedure on limited biological material of the human blood fluke Schistosoma mansoni"
<ul> <li>Files “CG_Ro_1_High Sensitivity DNA Assay_DE13805677_2019-06-20_09-10-48.pdf” and “CG_Ro_2_High Sensitivity DNA Assay_DE13805677_2019-06-20_10-12-12.pdf” uncropped files used in figure 2</li> <li>File “gel qpcr test input sds_01.tif” : uncropped file used in figure 8.</li> <li>File "20200612-1_Report.pdf" : qPCR report for inputs 1µL and available chromatine ("Row7"), figure 6 </li> <li>File "20200919-1_Report.pdf" : qPCR report for for testing SDS after Tn5, figure 7B and figure 8</li> <li>File "20200921-1_Report.pdf" : qPCR report for for comparing inputs with enzyme of Diagenode kit and our protocol with other enzyme Tn5 </li> <li>File "wilcoxon_curves.tgz" contains compressed versions of R-script "wilcoxon_curves.Rmd" that was used to compared metagene profiles and generate "wilcoxon_curves.html" and underlying ressources that are also in this compressed archive</li> </ul> <p>Produced at IHPE (http://ihpe.univ-perp.fr)</p>
Appendix 1 to "The Status of Biological Invasions and their Management in South Africa in 2022"—Species level pathway data
<p>SANBI and CIB 2023. Appendix 1 to "The Status of Biological Invasions and their Management in South Africa in 2022"—Species level pathway data. South African National Biodiversity Institute, Kirstenbosch and DSI-NRF Centre of Excellence for Invasion Biology, Stellenbosch. http://dx.doi.org/10.5281/zenodo.8217192</p> <p>For more details see: http://iasreport.sanbi.org.za</p> <p>For the report itself see: http://dx.doi.org/10.5281/zenodo.8217182</p>
Targeting fin whale conservation in the North-Western Mediterranean Sea: Insights on movements and behaviour from biologging and habitat modelling
<p>Biologging and habitat modelling are key tools supporting the development of conservation measures and mitigating the effects of anthropogenic pressures on marine species. Here, we analysed satellite telemetry data and foraging habitat preferences in relation to chlorophyll-a productivity fronts to understand the movements and behaviour of endangered Mediterranean fin whales (<em>Balaenoptera physalus)</em> during their spring-summer feeding aggregation in the North-Western Mediterranean Sea. Eleven individuals were equipped with Argos satellite transmitters across three years, with transmissions averaging 23.5 ± 11.3 days. Hidden Markov Models were used to identify foraging behaviour, revealing how individuals showed consistency in their use of seasonal core feeding grounds; this was supported by the distribution of potential foraging habitat. Importantly, tracked whales spent most of their time in areas with no explicit protected status within the study region. This highlights the need for enhanced time- and place-based conservation actions to mitigate the effects of anthropogenic impacts for this species, notably ship strike risk and noise disturbance in an area of exceptionally high maritime traffic levels. These findings strengthen the need to further assess critical habitats and Important Marine Mammal Areas that are crucial for focussed conservation, management, and mitigation efforts.</p>
Appendix 7 to "The Status of Biological Invasions and their Management in South Africa in 2022"—The Species List for the Prince Edward Islands
<p>SANBI and CIB 2023. Appendix 7 to "The Status of Biological Invasions and their Management in South Africa in 2022"—The Species List for the Prince Edward Islands. South African National Biodiversity Institute, Kirstenbosch and DSI-NRF Centre of Excellence for Invasion Biology, Stellenbosch. http://dx.doi.org/10.5281/zenodo.8217229</p> <p> </p> <p>For more details see: http://iasreport.sanbi.org.za<br> For the report itself see: http://dx.doi.org/10.5281/zenodo.8217182</p>
Enhancing comparative T-cell receptor repertoire analysis in small biological samples through pooling homologous cell samples from multiple mice
<p>All data files used to generate the figures in the paper are shared in this project.</p> <p>Scripts are available on <a href="https://github.com/i3-unit/CRM_24" target="_blank" rel="noopener">GitHub</a>.</p>
Mechanistic interactions as the origin of modularity in biological networks
<p>Biological networks are often modular. Explanations for this peculiarity either assume an adaptive advantage of a modular design such as higher robustness, or attribute it to neutral factors such as constraints underlying network assembly. Interestingly, most insights on the origin of modularity stem from models in which interactions are either determined by highly simplistic mechanisms or have no mechanistic basis at all. Yet, empirical knowledge suggests that biological interactions are often mediated by complex structural or behavioural traits. Here, we investigate the origins of modularity using a model in which interactions are determined by potentially complex traits. Specifically, we model system elements - such as the species in an ecosystem - as finite-state machines (FSMs) and determine their interactions by means of communication between the corresponding FSMs. Using this model, we show that modularity likely emerges for free. We further find that the more modular an interaction network is, the less complex are the traits that mediate the interactions. Altogether, our results suggest that the conditions for modularity to evolve may be much broader than previously thought.</p>
Genomics polymorphisms of Staphylococcus aureus strain NCTC 8325 in the lab stock maintained at TUM (WT), after 30 passes in BHI media (D) and after 30 passes detecting 4 -fold MIC increase to isocyanide -code I16- 3 biological replicates (A,B,C), and 3 independent colonies sequenced per replicate at the end of the experiment.
<p>Genomics polymorphisms of Staphylococcus aureus strain NCTC 8325 in the lab stock maintained at TUM (WT), after 30 passes in BHI media (D) and after 30 passes detecting 4 -fold MIC increase to isocyanide -code I16- 3 biological replicates (A,B,C), and 3 independent colonies sequenced per replicate at the end of the experiment. Determined from Illumina shotgun genomic sequencing datasets, mapping and analyses vs the reference genome of the strain https://www.ncbi.nlm.nih.gov/nuccore/NC_007795.1/</p>
Figure 5 in Are fisheries regulations influencing the biology and reproduction of the surmullet Mullus surmuletus Linnaeus, 1758 on the south-eastern coasts of France (NW Mediterranean)?
Figure 5. – Mean gonado-somatic index (GSI, %) of Mullus surmuletus with size (LT, cm) by sex.
Figure 3 in Aculus taihangensis (Acari: Prostigmata: Eriophyidae), a potential biological control agent identified from the highly invasive pest plant, tree of heaven, in Türkiye
Figure 3. Aculus taihangensis – Deutogyne: A. Coxigenital region, B. Internal genitalia.
Figure 4 in Breeding biology of the Maguari Stork Ciconia maguari (Aves, Ciconiidae) in the Pampa, and an outline in other Brazilian biomes
Figure 4. Seasonal occurrence of records of the Maguari Stork (Ciconia maguari) involving juveniles in the Pampa biome, in Rio Grande do Sul state, southern Brazil. Records were obtained by citizens and gathered in the WikiAves database in June 2020. Arabic numerals after each month represent 10-days long periods – (I):– days 1-10, (II): days 11-20, (III): days 21-31 of each month.
Intrinsically disordered Prosystemin discloses biologically active repeat motifs
<p>Dataset referred to "Intrinsically disordered Prosystemin discloses biologically active repeat motifs".</p> <p>Abstract: The in-depth studies over the years on the defence barriers by tomato plants have shown that the Systemin peptide controls the response to a wealth of environmental stress agents. This multifaceted stress reaction seems to be related to the intrinsic disorder of its precursor protein, Prosystemin (ProSys). Since latest findings show that ProSys has biological functions besides Systemin sequence, here we wanted to assess if this precursor includes peptide motifs able to trigger stress-related pathways. Candidate peptides were identified in silico and synthesized to test their capacity to trigger defence responses in tomato plants against different biotic stressors. Our results demonstrated that ProSys harbours several repeat motifs which triggered plant immune reactions against pathogens and pest insects. Three of these peptides were detected by mass spectrometry in plants expressing ProSys, demonstrating their effective presence in vivo. These experimental data shed light on unrecognized functions of ProSys, mediated by multiple biologically active sequences which may partly account for the capacity of ProSys to induce defense responses to different stress agents.</p>
Kuhlia rupestris, juvenile. © E. Vigneux. Source: Keith et al., 1999. in Biology of jungle perch, Kuhlia rupestris, identification of threats and knowledge gaps to improve local and global management
Kuhlia rupestris, juvenile. © E. Vigneux. Source: Keith et al., 1999.
Figure 4 in Population biology of the fiddler crab Uca maracoani (Crustacea, Ocypodidae) inhabiting an impacted mangrove area on the southern coast of São Paulo state, Brazil
Figure 4. Frequency of juveniles (%) of Uca maracoani by month.
Annotation files for B. asplanchnoidis genome (Stelzer et al. 2021, BMC Biology)
<p>This dataset contains the annotation files for the genome of Brachionus asplanchnoidis (Rotifera).</p> <p>The genome has been published here:</p> <p>Stelzer, C.P., Blommaert, J., Waldvogel, A.M. <em>et al.</em> Comparative analysis reveals within-population genome size variation in a rotifer is driven by large genomic elements with highly abundant satellite DNA repeat elements. <em>BMC Biol</em> <strong>19</strong>, 206 (2021).</p> <p>https://doi.org/10.1186/s12915-021-01134-w</p> <p> </p>
Integrative processing in artificial and biological vision predicts the perceived beauty of natural images
<p><em>Data, code, and materials for Nara & Kaiser (2023). </em></p> <p><em>Preprint: </em><a href="https://www.biorxiv.org/content/10.1101/2023.05.05.539579v1">https://www.biorxiv.org/content/10.1101/2023.05.05.539579v1</a></p> <p>Paper: <a href="https://doi.org/10.1126/sciadv.adi9294">https://doi.org/10.1126/sciadv.adi9294</a></p> <p>In this version (v2) of the repository, we:</p> <ul> <li>fixed an error in the fMRI data, where only the data from one participant, instead of all participants was uploaded previously - now all data are available,</li> <li>added brain masks (extracted by SPM) for each participant, and</li> <li>added realignment parameter text files (created by SPM) to the functional data for each participant.</li> </ul>
Individual project on theme "Cervus L." (MOOC: CompTech in biology)
<p><strong><span>Данный кейс является результатом реализации индивидуального проекта </span></strong><em><span>Попова Игоря</span></em><strong><span> по теме "</span></strong><em><span>C</span></em><em><span>ervus</span></em><em><span> </span></em><span>L</span><span>.</span><strong><span>" в рамках онлайн курса "Компьютерные технологии в биологии" (автор – А.В. Ваганов) (https://stepik.org/course/60859/promo)</span></strong></p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.