Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
4,359
datasets available to search
ShareScore release 0.9.0
Dataset results
4,359 results for “Insulin”
Data from: Perinatal lead (Pb) exposure results in sex-specific effects on food intake, fat, weight, and insulin response across the murine life-course
Open the record for dataset details and reuse information.
Data from: Hypoglycemia Following intravenous insulin plus glucose for hyperkalemia in patients with impaired renal function
Open the record for dataset details and reuse information.
Data from: Establishment of a refined oral glucose tolerance test in pigs, and assessment of insulin, glucagon and glucagon-like peptide-1 responses
Open the record for dataset details and reuse information.
Data from: Insulin sensitizers for improving endocrine metabolism in overweight women with PCOS: a network meta-analysis
Open the record for dataset details and reuse information.
Data from: Immune response and insulin signalling alter mosquito feeding behaviour to enhance malaria transmission potential
Open the record for dataset details and reuse information.
Classification of Type 2 Diabetes Genetic Variants and a Novel Genetic Risk Score Association with Insulin Clearance
Open the record for dataset details and reuse information.
Data from: Maternal obesity increases insulin resistance, low-grade inflammation and osteochondrosis lesions in foals and yearlings until 18 months of age
Open the record for dataset details and reuse information.
Data from: Ablation of insulin-producing cells prevents obesity but not premature mortality caused by a high-sugar diet in Drosophila
Open the record for dataset details and reuse information.
['Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men']
['Physical inactivity is a risk factor for insulin resistance. We examined the effect of nine days of bed rest on basal and insulin stimulated expression of genes potentially involved in insulin action by applying hypothesis-generating microarray in parallel with candidate gene real-time PCR approaches in 20 healthy, young men. Furthermore, we investigated whether bed rest affected DNA methylation in the promoter region of the peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) gene. Subjects were re-examined after four weeks of retraining. Findings: Bed rest induced insulin resistance and altered the expression of more than 4,500 genes. These changes were only partly normalized after four weeks of retraining. Pathway analyses revealed significant down-regulation of 34 pathways, predominantly those of genes associated with mitochondrial function including PPARGC1A. Despite induction of insulin resistance, bed rest resulted in a paradoxically increased response to acute insulin in the general expression of genes, particularly those involved in inflammation and endoplasmatic reticulum (ER) stress. Furthermore, bed rest changed gene expressions of several insulin resistance and diabetes candidate genes. We also observed a trend toward increased PPARGC1A DNA methylation after bed rest. Conclusions: Impaired expression of PPARGC1A and other genes involved in mitochondrial function as well as a paradoxically increased response to insulin of genes involved in inflammation and ER stress may contribute to the development of insulin resistance induced by bed rest. Lack of complete normalization of changes after four weeks of exercise retraining underscores the importance of maintaining a minimum of daily physical activity.']
Genetic ablation of miR-33 increases food intake, enhances adipose tissue expansion, and promotes obesity and insulin resistance
GEO Series GSE109327. Mus musculus. 48 samples. Type: Expression profiling by array.
Reduced circulating insulin enhances insulin sensitivity in old mice and extends lifespan
GEO Series GSE99440. Mus musculus. 39 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq reveals transcriptome changes which could be responsible to insulin in insulin resistance states
GEO Series GSE205460. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
insulin resistant duodenum vs. non-insulin resistant duodenum
GEO Series GSE147562. Homo sapiens. 14 samples. Type: Expression profiling by array.
STAT1 Dissociates Adipose Tissue Inflammation from Insulin Sensitivity in Obesity
GEO Series GSE153337. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Nutritional Strategy to Prevent Fatty Liver and Insulin Resistance Independent of Obesity by Reducing GIP Responses
GEO Series GSE54723. Mus musculus. 14 samples. Type: Expression profiling by array.
A Pathobiological Role of the Insulin Receptor in CLL.
GEO Series GSE26526. Homo sapiens. 19 samples. Type: Expression profiling by array.
Human skeletal muscle gene expression analysis on Lean, obese insulin sensitive, obese insulin resistant and obese Type II diabetic subjects
GEO Series GSE73034. Homo sapiens. 28 samples. Type: Expression profiling by array.
Acyl-CoA synthetase 1 in differentiated adipocytes from small for gestational age neonates: Putative association with fetal programming of cellular insulin sensitivity and lipid content [Set1B: adipog
GEO Series GSE64699. Homo sapiens. 28 samples. Type: Expression profiling by array.
Diabetes Remission Using Glucose-Responsive Insulin-Producing Human α-Cells
GEO Series GSE117454. Homo sapiens. 39 samples. Type: Expression profiling by high throughput sequencing.
Human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathy
GEO Series GSE288708. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.