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2,194
datasets available to search
ShareScore release 0.9.0
Dataset results
2,194 results for “Diffusers”
RNA sequencing/Gene expression studies of N-glycosylation inhibitors in diffuse lymphoma
GEO Series GSE212337. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
SAGA/ATAC complexes sustain aberrant chromatin regulation and promote tumorigenesis in diffuse midline glioma [CUT&Run]
GEO Series GSE318286. Homo sapiens. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
IDHwt and IDHmut adult-type diffuse gliomas display distinct alterations in ribosome biogenesis and 2’O-methylation of ribosomal RNA
GEO Series GSE224104. Homo sapiens. 94 samples. Type: Other.
Chip-chip from human diffuse large B cell lymphoma cell lines with IRF8
GEO Series GSE30357. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Posttransplant diffuse large B-cell lymphoma: new genetic findings
GEO Series GSE69440. Homo sapiens. 38 samples. Type: Genome variation profiling by SNP array.
SMYD3 promotes aerobic glycolysis in diffuse large B-cell lymphoma via H3K4me3-mediated PKM2 transcription
GEO Series GSE207262. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
The tumor associated antigen PRAME exhibits dualistic functions that are targetable in diffuse large B cell lymphoma
GEO Series GSE190403. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.
TP53 wild type/PPM1D mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist
GEO Series GSE189152. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Artesunate inhibits the cell viability of diffuse large B cell lymphoma cells by increasing the susceptibility to ferroptosis (RNA-seq).
GEO Series GSE260741. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
OLIG2 maintenance is not essentially required for diffuse intrinsic pontine glioma cell line growth but regulates tumor phenotypes
GEO Series GSE157158. Homo sapiens. 19 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
SAGA/ATAC complexes sustain aberrant chromatin regulation and metabolic programs in diffuse midline glioma
GEO Series GSE317235. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Diffuse Glioma (GLASS Consortium)
Whole genome or whole exome sequencing analysis of temporally separated diffuse glioma tumor/normal pairs from 222 adult patients. The cases here are only those under the age of 40 years old.
Diffuse Large B-Cell Lymphoma Duke
Whole-exome sequencing of 1,001 Diffuse Large B Cell Lymphoma (DLBCL) tumors (N = 1001) and paired-normal tissue (N = 400). The cases here are only those under the age of 40 years old.
IDH-mutated Diffuse Glioma MSK
Targeted sequencing of 73 IDH-mutated low-grade gliomas and their matched normal pairs via MSK-IMPACT. The cases here are only those under the age of 40 years old.
Next generation sequencing of diffuse intrinsic pontine glioma samples to identify recurrent mutations, variations, and expression patterns to define novel therapies
Diffuse intrinsic pontine glioma (DIPG) is an extremely rare (~350 cases/year) and universally fatal childhood brain cancer. Standard clinical strategies such as chemotherapy and radiotherapy show only transient improvement in patient condition and result in negligible change in survival, DIPG remains at below 1% survival after 5 years. Prioritization of panobinostat through previous cooperative work resulted in a phase 1 clinical trial. Nonetheless, new therapies for DIPG must be identified to further dramatically change the statistics for DIPG. To identify novel therapy strategies for DIPG, we performed whole exome(16 new samples, 22 previously published samples, 38 in total with 26 matched normal) and RNA deep sequencing (17 new samples, 11 previously published samples) on a cohort of new patient samples. Sequencing results aid in the identification of recurrent mutations/variations and endotypic expression profiling to identify new therapeutic and treatment strategies for DIPG.
Characterizing TP53 and PPM1D Mutations as Resistance Drivers to Radiation Therapy in Diffuse Intrinsic Pontine Gliomas
Pediatric high-grade gliomas (pHGGs), encompassing diffuse midline gliomas (DMGs) and hemispheric tumors, represent the most common cause of cancer-related deaths in children age 0-14 years. Over the last decade, several landmark papers have revealed recurrent single nucleotide variants (SNVs) in the core histones H3.3 and H3.1, co-occurring with alterations in the TP53 signaling pathway and receptor tyrosine kinases (RTKs). However, the contribution of structural variants (SVs) to gliomagenesis has not been systematically explored. We performed a comprehensive analysis of whole genome sequencing (WGS) data on pediatric high-grade gliomas (pHGGs) from 179 children, including 61 hemispheric tumors and 118 diffuse midline gliomas, or DMGs, of which 61 are novel to this study. Among the DMGs, 84 (71%) were from pre-treatment biopsies including 33 obtained from the first multi-institutional North American clinical trial to incorporate diagnostic biopsies. This represents the largest cohort of pretreatment DMGs with whole genome sequencing to date. This large cohort of whole genome sequences provides an unparalleled opportunity to assess significantly recurrent structural variants in pHGG and their associations with driver SNVs and SCNAs.
The Keratin 17/YAP/IL6 Axis contributes to E-cadherin Loss and Aggressiveness of Diffuse Gastric Cancer
GEO Series GSE171879. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic priming using low-dose 5-azazcytidine in diffuse large B-cell lymphoma
GEO Series GSE190321. Homo sapiens. 28 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Clinical and molecular characterization of splenic diffuse red pulp lymphomas [Agilent]
GEO Series GSE65060. Homo sapiens. 13 samples. Type: Genome variation profiling by genome tiling array.
Diffusion-based subsurface multiphysics monitoring and forecasting
<p><span>We develop a novel monitoring and forecasting framework using video diffusion </span><span>models of subsurface changes due to, for example, CO</span><span>2</span> <span>injection. In this letter, we present the relevant dataset to the paper. </span></p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.