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3,139 results for “fitting”
Dataset of the bacterial fitness estimation values and mutation identifications from: Rapid decline of adaptation of Pseudomonas fluorescens to soil biotic environment
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Data from: Linking system-wide impacts of RNA polymerase mutations to the fitness cost of rifampin resistance in Pseudomonas aeruginosa
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Data from: Modeling and quantifying frequency-dependent fitness in microbial populations with cross-feeding interactions
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Host plant defense produces species-specific alterations to flight muscle protein structure and flight-related fitness traits of two armyworms
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Influence of genetic compatibility on offspring fitness in the red-backed toadlet
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Bayesian tip-dated phylogenetics in paleontology: topological effects and stratigraphic fit
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The effect of environmental heterogeneity on the fitness of antibiotic resistance mutations in Escherichia coli
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Growth rate assays reveal fitness consequences of β-lactamases
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Selected modeled output variables from ROMS 4DVAR model fits for the P1706 and P1604 CCE-LTER process cruises
Values for Kz and w were extracted from a three-dimensional physical model (9 km horizontal resolution, 42 vertical layers) developed using the Regional Ocean Modeling System (ROMS) four-dimensional variational data assimilation system (4DVAR) (Moore et al., 2011), then depth-interpolated linearly to calculate values at the MLD. Initial and boundary conditions were taken from the California Current System Reanalysis product produced by the University of California, Santa Cruz. Surface forcing was taken from the 9-km resolution Coupled Ocean/Atmosphere Mesoscale Prediction System (COAMPS) (Doyle, Jiang, Chao, & Farrara, 2009; Hodur, 1997). We assimilated satellite remote sensing products (sea surface height from Ssalto/Duacs and sea surface temperature from AVHRR) and in situ temperature and salinity data vertical profiles collected during CTD measurements on our cruise. Assimilated data were used to update model initial conditions and surface forcing to generate a dynamically-consistent month-long model fit covering the duration of each cruise and producing 8-hr averaged outputs. For detailed descriptions of our ROMS 4DVAR approach, see (Song et al., 2012) and (Miller, Song, & Subramanian, 2015). Kz and w were interpolated to CTD cast locations from the 9-km ROMS 4DVAR solution using bilinear 2D interpolation from the four points comprising the nearest neighbors to the cast coordinates.
Selecting for Chlamydomonas reinhardtii fitness in the KSC Veggie Unit
The Space Algae Experiment Verification Test completed a competitive growth selection on mutagenized microalgae in a series of batch cultures that were passaged for three growth cycles. The experiment was conducted with ground control conditions similar to those actually used in spaceflight. Cultures were limited in growth rate due to gas permeable membranes to provide oxygen and carbon dioxide exchange and a lack of agitation to mix the cells throughout the liquid media. Two strains were grown and three biological replicates were completed for each strain. Specific variables (factors) tested were: 1) The effect of UVC mutagenesis was tested by sampling the algae cultures prior to mutagenesis. 2) The sensitivity of different strains was tested by conducting the experiment with a wild-type and cell wall mutant (cw15) strain. 3) The effect of competitive growth was tested by sampling each biological replicate experiment at the end of each growth cycle. 4) The effect of live culture storage in the dark was tested by sampling each growth cycle twice. At the time of passage a sample of cells was pelleted and frozen. The cultures were then stored in the dark in a Cargo Transport Bag (CTB) to simulate storage on the ISS and return of cultures. This factor tested whether cultures could be stored alive in the dark or if samples needed to be fixed at the time of passage in order to get an accurate representation of the genetic variation in each cycle of growth. Paired-end whole genome sequencing was completed for 38 samples: 2 strains pre mutagenesis and 2 strains X 3 biological replicates X 3 growth cycles X 2 storage conditions.
Migration speed of captured breast cancer subpopulations correlates with metastatic fitness
GEO Series GSE188224. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Identifying non-genetic determinants of malignant clonal fitness at single cell resolution (primary leukaemia barcode-seq)
GEO Series GSE161657. Mus musculus; synthetic construct. 14 samples. Type: Other.
De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia
GEO Series GSE106714. Mus musculus. 45 samples. Type: Expression profiling by high throughput sequencing.
RNA m6A methylation suppresses insect juvenile hormone degradation to minimize fitness costs in response to a pathogenic attack
GEO Series GSE247107. Plutella xylostella. 12 samples. Type: Other.
Longitudinal dynamics of clonal haematopoiesis identifies gene-specific fitness effects
GEO Series GSE178936. Homo sapiens. 261 samples. Type: Other.
Natural Variation in the Fitness Consequences of Gene Amplification in Wild Saccharomyces cerevisiae Isolates [RNA-seq]
GEO Series GSE171585. Saccharomyces cerevisiae. 45 samples. Type: Expression profiling by high throughput sequencing.
Involvement of transcription elongation factor GreA in Mycobacterium tuberculosis viability, antibiotic susceptibility, and intracellular fitness
GEO Series GSE143764. Mycolicibacterium smegmatis MC2 155. 10 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection- Barseq6 (anaerobic LB, GMM, zinc, Nmedia, protamine- second set)
GEO Series GSE261873. Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150; Salmonella enterica subsp. enterica serovar Typhi str. Ty2; Salmonella enterica subsp. enterica serovar Typhimurium str. D23580; Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74. 28 samples. Type: Other.
SARS-CoV-2 Variant of Concern Fitness and Adaptation in Primary Human Airway Epithelia
GEO Series GSE253698. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing.
Multiclonal competition reveals impaired cell fitness of GATA2 deficient cells [RNA-seq]
GEO Series GSE282250. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.