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5,794 results for “exposures”
Data from: Changes in predator exposure, but not diet induce phenotypic plasticity in scorpion venom
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Data from: Maternal pathogen exposure causes diet- and pathogen-specific transgenerational costs
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Data from: Decrease in ribosomal RNA in Candida albicans induced by serum exposure
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Data from: Exposure to an environmental estrogen breaks down sexual isolation between native and invasive species
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Noise pollution: acute noise exposure increases susceptibility to disease and chronic exposure reduces host survival
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Data from: Mercury exposure in an endangered seabird: long-term changes and relationships with trophic ecology and breeding success
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Data from: Prozac in the water: chronic fluoxetine exposure and predation risk interact to shape behaviors in an estuarine crab
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Data from: Honey bees and neonicotinoid-treated corn seed: contamination, exposure, and effects
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Maintenance of hindgut reabsorption during cold exposure is a key adaptation for Drosophila cold tolerance
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Data from: The association between exposure to environmental bisphenol A and gonadotropic hormone levels among men
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Dataset for: Assessing pesticides exposure effects on the reproductive performance of a declining aerial insectivore
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Data set for: Long-term Perfluorooctanesulfonic acid (PFOS) exposure alters anxiety-like behaviour but not boldness in zebrafish (Danio rerio)
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The Ant Who Cried Wolf? Short-Term Repeated Exposure to Alarm Pheromone Reduces Behavioral Response in Argentine Ants
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As the Wind Blows: The Effects of Long-Term Exposure to Air Pollution on Mortality
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IMERG and LHASA Global Landslide Exposure Maps 1.0
The Landslide Hazard Assessment for Situational Awareness (LHASA) model identifies locations with high potential for landslide occurrence at a daily temporal resolution. LHASA combines satellite‐based precipitation estimates with a landslide susceptibility map derived from information on slope, geology, road networks, fault zones, and forest loss. When rainfall is considered to be extreme and susceptibility values are moderate to very high, a “nowcast” is issued to indicate the times and places where landslides are more probable.This archive contains GeoTIFF Rasters that are a 16-year average (beginning of 2001 - end of 2016). The spatial coverage is from 72°N to 60°S latitude, and 180°W to 180°E longitude, based on IMERG Ver06B from the aforementioned time interval. The provided global maps of exposure to landslide hazards, are at a 30x30 arc-second resolution. These maps show the estimated exposure of population, roads, and critical infrastructure (hospitals/clinics, schools, fuel stations, power stations & distribution facilities) to landslide hazard, as modeled by the NASA LHASA model.The data collection consists of eight files, covering the aforementioned spatial and temporal ranges, totaling approximately 20.3 GB (~2.5 GB each): (1): Landslide hazard (annual average; Units: Nowcasts.yr-1) (2): Landslide hazard (annual standard deviation; Units: Nowcasts.yr-1) (3): Population exposure (annual average; Units: Person-Nowcasts. yr-1. km-2) (4): Population exposure (annual standard deviation; Units: Person-Nowcasts. yr-1. km-2) (5): Road exposure (annual average; Units: Nowcasts.km.yr-1.km-2) (6): Road exposure (annual standard deviation; Units: Nowcasts.km.yr-1.km-2) (7): Critical infrastructure exposure (annual average; Units: Nowcasts.element.yr-1.km-2) (8): Critical infrastructure exposure (annual standard deviation; Units: Nowcasts.element.yr-1.km-2)
Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation. RNA was isolated and microarray hybridization performed for gene expression analysis. 5 samples were analyzed: 2 controls at 2 months 1 2 Gy at 2 months and 2 7 Gy at 2 months
miRNA signature detection and countermeasures against HZE radiation exposure for tissue degeneration-Plasma
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has shown both TGF xce xb2 signaling pathways and miRNAs have a critical impact on defining health risks with and without space irradiation. We hypothesize that circulating microRNA (miRNA) signatures are driving microvascular disease and muscle degeneration associated with accelerating aging and will be enhanced by exposure to the space environment (radiation and microgravity). We investigated this hypothesis both in vivo and in vitro and test novel antagonist therapies to these miRNA signatures as countermeasures to reduce space radiation-induced health risks. A comprehensive Systems Biology approach was used to examine the influence by high atomic number by high (H) atomic number (Z) and energy (E) (HZE) irradiation. To simulate low-dose exposure due to galactic cosmic rays (GCR) we used the ions energy and doses determined by a NASA consensus formula of 7 different ions to represent GCR (referred to as GCR sim model). To simulate high-dose radiation exposure due to solar particle events (SPE) we used an acute dose of SPE simulated beam at 1Gy which has energies ranging from 50MeV to 150MeV. C57BL/6 wild-type mice were utilized for irradiation with our established simulated microgravity model (hindlimb suspension model) and an in vitro 3D microvasculature tissue model under simulated microgravity (clinostat) conditions will also be irradiated. To expand on the circulating miRNA signature determined from our preliminary data we determined a group of conserved miRNAs which are commonly being regulated in the majority of the organs and tissues throughout the host using our established techniques. MiRNA-sequencing on serum (before IR and at time of sacrifice) liver heart and muscle tissue for all radiation groups revealed the key circulating miRNA signature (consisting of multiple miRNAs) impacting disease risk. Collectively understanding of how whole body space radiation impacts microvascular and tissue degeneration through circulating miRNAs will greatly enhance health risk prognostication and provide possible new mechanisms for protection against space radiation.
Mouse fecal microbiome after exposure to high LET radiation
Space travel is associated with continuous low-dose-rate exposure to high Linear Energy Transfer (LET) radiation. Pathophysiological manifestations after low-dose radiation exposure are strongly influenced by non-cytocidal radiation effects including microbiome and cellular gene expression. Using a mouse model for exposure to high LET radiation we observed substantial changes in the composition and functional potential of the microbiome. These were paralleled by changes in the abundance of multiple metabolites which were related to the enzymatic activity of the altered metagenome by means of metabolic network modeling. There was a complex dynamic in microbial and metabolic composition at different radiation doses suggestive of transient dose-dependent interactions between microbial ecology and signals from the host s cellular damage repair processes. Functional shifts included features associated with dysbiosis at the onset of chronic inflammatory responses which could prMouse fecal microbiome after exposure to high LET radiatione-dispose space travelers to systemic long-term health risks.
Gene expression in human peripheral blood 48 hours after exposure to ionizing radiation
Analysis of human peripheral blood 48 hours after irradiation ex vivo with graded doses of gamma rays. Results have been used in building and testing classifiers to predict exposure dose for use in radiological triage and also provide insight into immune cell responses. Results were compared with those from earlier times and from patients exposed in vivo. Peripheral blood from 5 healthy donors was exposed ex vivo to 0. 0.5 2 5 or 8 Gy gamma-rays and gene expression was analyzed up to 48 hours after exposure.
Transcription profiling of Drosophila after exposure to microgravity in the International Space Station and in a microgravity simulator
Larvae-Pupae transition flies (Drosophila) were recovered and transport for 3 days at 12-14C to arrest development until the launch site then exposed to RT (18-20C) for some hours including the launch and trip to the International Space Station then pupae were exposed to microgravity in the ISS for 4 days and a half at 22C. Finally pupae were fixed on acetone and frozen until recovery on Earth. Four groups of samples: 1 ISS (+ground control) as described 2 RPM (microgravity simulator on Earth) as described 3 RPM without constrains (No MAMBA container and only 5 days exposure without cold transport) and 4 centrifuge 10g without constrains control.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.