Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
312
datasets available to search
ShareScore release 0.9.0
Dataset results
312 results for “Confinement”
The confined environment in microfluidic reveals a hidden role of self-organizing extracellular-matrix in hepatic commitment and organoid formation of hiPSCs
GEO Series GSE159926. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Mechanical Confinement Promotes Heat Resistance of Hepatocellular Carcinoma via SP1/IL4I1/AHR Axis
GEO Series GSE235351. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Chromatin opening by p53 is confined by Trim24 in a histone methylation-dependent manner [RNA-seq]
GEO Series GSE200581. Mus musculus. 49 samples. Type: Expression profiling by high throughput sequencing.
Paracrine orchestration of intestinal tumorigenesis by a confined mesenchymal niche
GEO Series GSE142431. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.
Engineering spatially-confined conduits to tune nerve self-organization and allodynic responses via YAP-mediated mechanotransduction
GEO Series GSE280040. Rattus norvegicus. 12 samples. Type: Expression profiling by high throughput sequencing.
Cell confinement memory initiates heritable loss of chromosomes and a persistently dysregulated division program
GEO Series GSE317816. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Uridylation of RNA-hairpins by Tailor confines the emergence of novel miRNAs in Drosophila
GEO Series GSE66213. Drosophila melanogaster; synthetic construct. 22 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Loss of skin and mucosal CXCR3+ resident memory T cells causes irreversible tissue-confined immunodeficiency in HIV
GEO Series GSE184320. Homo sapiens. 28 samples. Type: Expression profiling by high throughput sequencing; Other.
Mechanical confinement prevents ectopic platelet release
GEO Series GSE264159. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Intratumoral antigen-signalling traps CD8+ T cells to confine exhaustion to the tumour site (bulk TCR-Seq)
GEO Series GSE266360. Mus musculus. 44 samples. Type: Other.
Functional maps of a genomic locus reveal confinement of an enhancer by its target gene
GEO Series GSE275427. Mus musculus. 1057 samples. Type: Other; Genome binding/occupancy profiling by high throughput sequencing.
Spatially confined sub-tumor microenvironments orchestrate pancreatic cancer pathobiology
GEO Series GSE166571. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
Targeting RhoA nuclear mechanoactivity rejuvenates aged hematopoietic stem cells [bulk ATAC-seq confinement]
GEO Series GSE269396. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Dynamic cell culture in bubble-confined cell array
GEO Series GSE11191. Mus musculus. 6 samples. Type: Expression profiling by array.
Intratumoral antigen-signalling traps CD8+ T cells to confine exhaustion to the tumour site (scRNA-Seq)
GEO Series GSE266361. Mus musculus. 49 samples. Type: Expression profiling by high throughput sequencing; Other.
WDR5 activity regulates nuclear changes and migration of acute lymphoblastic leukemia cells across confined spaces [Jurkat]
GEO Series GSE193440. Homo sapiens. 7 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Tissue confinement regulates cell growth and size in epithelia
GEO Series GSE227906. Canis lupus familiaris. 6 samples. Type: Expression profiling by high throughput sequencing.
Water level response in wells to dynamic shaking in confining unconsolidated sediments: a laboratory study
<p class="15"><span>This article focuses on laboratory experiments designed to investigate the influence of dynamic shaking on water level fluctuation in wells of unconsolidated sediments. A large flume filled with natural sandy sediments was subjected to horizontal dynamic loading at different frequencies (0.5-15Hz) and accelerations (0.1g, 0.15g, 0.25g and 0.5g), generated by a shaking table. Thus, the change in characteristics of the water and saturated sediments were investigated, including how water level and hydraulic properties changed over time, are of significant interest. A range of water level changes following the oscillating pore pressure for hydrostatic and hydrodynamic (flowing) conditions were observed: oscillation, step-rise, step-rise with oscillation, and step-drop with oscillation, similar to those observed in nature after earthquakes. We find that water level declines occur when the imposed frequency is less than 2Hz, while the acceleration has weak correlation on the water level change when it is less than 0.5g. Sinusoidal wave propagation reduces hydraulic conductivity first sharply which then stabilizes at a constant value with a slight increase. Heterogeneous consolidation, mechanical resonance, compaction, dilation, and re-packing of the grain structure may constitute a physically plausible mechanism for water level fluctuations and hydraulic parameters adjustment. Laboratory experiments can therefore provide quantitative and process-oriented approach to better understand water level response to seismic waves.This article focuses on laboratory experiments designed to investigate the influence of dynamic shaking on water level fluctuation in wells of unconsolidated sediments. A large flume filled with natural sandy sediments was subjected to horizontal dynamic loading at different frequencies (0.5-15Hz) and accelerations (0.1g, 0.15g, 0.25g and 0.5g), generated by a shaking table. Thus, the change in characteristics of the water and saturated sediments were investigated, including how water level and hydraulic properties changed over time, are of significant interest. A range of water level changes following the oscillating pore pressure for hydrostatic and hydrodynamic (flowing) conditions were observed: oscillation, step-rise, step-rise with oscillation, and step-drop with oscillation, similar to those observed in nature after earthquakes. We find that water level declines occur when the imposed frequency is less than 2Hz, while the acceleration has weak correlation on the water level change when it is less than 0.5g. Sinusoidal wave propagation reduces hydraulic conductivity first sharply which then stabilizes at a constant value with a slight increase. Heterogeneous consolidation, mechanical resonance, compaction, dilation, and re-packing of the grain structure may constitute a physically plausible mechanism for water level fluctuations and hydraulic parameters adjustment. Laboratory experiments can therefore provide quantitative and process-oriented approach to better understand water level response to seismic waves.</span></p>
Photo-induced receptor confinement drives ligand-independent GPCR signaling
<p>Cell-cell communication relies on the assembly of receptor-ligand complexes at the plasma membrane. The spatiotemporal receptor organization has a pivotal role in evoking cellular responses. We studied the clustering of heterotrimeric guanine nucleotide–binding protein (G protein)–coupled receptors (GPCRs) and established a photo-instructive matrix with ultra-small lock-and-key interaction pairs to control lateral membrane organization of hormone neuropeptide Y<sub>2</sub> receptors in living cells by light. Within seconds, receptor clustering was modulated in size, location, and density. After <em>in-situ</em> confinement, changes in cellular morphology, motility, and calcium signaling revealed ligand-independent receptor activation. This approach may enhance exploration of mechanisms in cell signaling and mechanotransduction.</p>
Highly stretchable conductors based on expanded graphite macro-confined in tubular rubber
<p>Content:<br> 1. Figure 2<br> 2. Figure 3<br> 3. Figure 4<br> 4. Figure 5<br> 5. Figure 6<br> 6. Figure 7<br> 7. Figure 8<br> Notes : This dataset is linked to Paper: ACS Applied Materials and Interfaces, DOI: 10.1021/acsami.7b08866<br> </p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.