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565 results for “ESCAPE”
Escaping ESKAPE resistance: In vitro and in silico studies of multifunctional carbamimidoyl-tethered indoles against antibiotic-resistant bacteria
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Data from: Morphology, performance and fluid dynamics of the crayfish escape response
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A Bayesian optimal escape model reveals bird species differ in their capacity to habituate to humans
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A molecular view on the escape of lipoplexed DNA from the endosome (no trajectories)
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Data from: Interacting effects of predation risk and resource level on escape speed of amphibian larvae along a latitudinal gradient
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Data from: Gene flow from domesticated escapes alters the life history of wild Atlantic salmon
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Escape from natural enemies depends on the enemies, the invader, and competition
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Neonicotinoid and sulfoximine pesticides differentially impair insect escape behaviour and motion detection
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Data from: A faster escape does not enhance survival in zebrafish larvae
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Data from: Lobelia siphilitica plants that escape herbivory in time also have reduced latex production
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Insight into the genetic population structure of wild red foxes in Poland reveals low risk of genetic introgression from escaped farm red foxes
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Data from: Escape from predators and genetic variance in birds
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Data from: Escaping peril: perceived predation risk affects migratory propensity
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Multimodal mechanosensing enables treefrog embryos to escape egg-predators
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Physiology and behavior under food limitation support an escape, not preparative, response in the nomadic Pine Siskin (Spinus pinus)
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Data from: Superfetation reduces the negative effects of pregnancy on the fast-start escape performance in live-bearing fish
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Data from: Parasite escape through trophic specialization in a species flock
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Data from: Cleaner fish escape salmon farms and hybridize with local wrasse populations
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Data from: Going with the flow: hydrodynamic cues trigger directed escapes from a stalking predator
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Data from: Within-host stochastic emergence dynamics of immune-escape mutants
Predicting the emergence of new pathogenic strains is a key goal of evolutionary epidemiology. However, the majority of existing studies have focussed on emergence at the population level, and not within a host. In particular, the coexistence of pre-existing and mutated strains triggers a heightened immune response due to the larger total pathogen population; this feedback can smother mutated strains before they reach an ample size and establish. Here, we extend previous work for measuring emergence probabilities in non-equilibrium populations, to within-host models of acute infections. We create a mathematical model to investigate the emergence probability of a fitter strain if it mutates from a self-limiting strain that is guaranteed to go extinct in the long-term. We show that ongoing immune cell proliferation during the initial stages of infection causes a drastic reduction in the probability of emergence of mutated strains; we further outline how this effect can be accurately measured. Further analysis of the model shows that, in the short-term, mutant strains that enlarge their replication rate due to evolving an increased growth rate are more favoured than strains that suffer a lower immune-mediated death rate ('immune tolerance'), as the latter does not completely evade ongoing immune proliferation due to inter-parasitic competition. We end by discussing the model in relation to within-host evolution of human pathogens (including HIV, hepatitis C virus, and cancer), and how ongoing immune growth can affect their evolutionary dynamics.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.