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1,324 results for “Soft tissue”
elliptical eumelanosomes in the feathers near the skull (b, c), neck (d, e), humerus (f, g), and ulna (h, i, j); and large oval and elliptical eumelanosomes in the feathers near the tibiotarsus (k, l). The subspherical phaeomelanosomes in the sheet-like soft tissue (m) appear to be less densely distributed than the melanosomes in the feathers. in A bizarre Jurassic maniraptoran theropod with preserved evidence of membranous wings
elliptical eumelanosomes in the feathers near the skull (b, c), neck (d, e), humerus (f, g), and ulna (h, i, j); and large oval and elliptical eumelanosomes in the feathers near the tibiotarsus (k, l). The subspherical phaeomelanosomes in the sheet-like soft tissue (m) appear to be less densely distributed than the melanosomes in the feathers.
Data from: Three-dimensional soft tissue preservation revealed in the skin of a non-avian dinosaur
<p>The most commonly preserved soft tissues associated with ornithischian dinosaurs are skin remains. The apparent resistance of hadrosaur skin to decay, and its abundance in the fossil record relative to that of other tetrapods, has been attributed to factors such as thickness and composition. Here we report additional intrinsic factors within hadrosaur skin: 3D‐preserved eumelanin‐bearing bodies, dermal cells and blood vessel fragments in an organic matrix composed of protein fossilization products. The skin is much thinner than that of living mammals of similar size. It is likely that the preservation of hadrosaur skin is related to the arrangement of the layers composing it.</p>
A closer look at high-energy X-ray-induced bubble formation during soft tissue imaging
<p>Improving the scalability of tissue imaging throughput with bright, coherent X-rays requires identifying and mitigating artifacts resulting from the interactions between X-rays and matter. At synchrotron sources, long-term imaging of soft tissues in solution can result in gas bubble formation or cavitation, which dramatically compromises image quality and integrity of the samples. By combining in-line phase-contrast cineradiography with <em>operando</em> gas chromatography, we were able to track the onset and evolution of high-energy X-ray-induced gas bubbles in ethanol-embedded soft tissue samples for tens of minutes (2 to 3 times the typical scan times). We demonstrate quantitatively that vacuum degassing of the sample during preparation can significantly delay bubble formation, offering up to a twofold improvement in dose tolerance, depending on the tissue type. However, once nucleated, bubble growth is faster in degassed than undegassed samples, indicating their distinct metastable states at bubble onset. Gas chromatography analysis shows increased solvent vaporization concurrent with bubble formation, yet the quantities of dissolved gases remain unchanged. Coupling features extracted from the radiographs with computational analysis of bubble characteristics, we uncover dose-controlled kinetics and nucleation site-specific growth. These hallmark signatures provide quantitative constraints on the driving mechanisms of bubble formation and growth. Overall, the observations highlight bubble formation as a critical, yet often overlooked hurdle in upscaling X-ray imaging for biological tissues and soft materials and we offer an empirical foundation for their understanding and imaging protocol optimization. More importantly, our approaches establish a top-down scheme to decipher the complex, multiscale radiation-matter interactions in these applications.</p>
Validation results of the soft tissue-informed kinematic solver on an in-vitro cadaver arm motion sequence
<p>This movie accompanies the paper in which the soft tissue-informed kinematic solver was introduced and validated. The validation was performed using three distinct experiments. The final validation experiment comprised the elbow joint. Hereto, a cadaver was scanned in a CT. The arm was scanned in 11 distinct positions, encompassing extension with pronation and supination, flexion at roughly 45, 90, and 135 degrees with the hand in neutral, fully pronated, and fully supinated positions. Dedicated skin regions were used as input. In the movie, the skin is illustrated in grey and the ground truth bony positions are shown in blue. The predicted positions of the humerus, ulna and, radius are indicated in red. </p>
Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues
ClinicalTrials.gov study NCT01757730. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Instrument Assisted Soft Tissue Mobilization Versus Dynamic Oscillatory Stretch Technique in Females Wearing High Heels
ClinicalTrials.gov study NCT06086600. IPD Sharing: NO. Countries: 1. Publications: 1.
A Study of Pazopanib and Durvalumab for Metastatic Soft Tissue Sarcoma
ClinicalTrials.gov study NCT03798106. IPD Sharing: NO. Countries: 1. Publications: 0.
Imatinib Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma or Bone Sarcoma
ClinicalTrials.gov study NCT00031915. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Soft Tissue Width and Abutment Height Influence Peri-implant Bone Resorption
ClinicalTrials.gov study NCT03229005. IPD Sharing: NO. Countries: 1. Publications: 2.
FLuoresence Image Guided Surgery With A VEGF-targeted Tracer in Soft-tissue Sarcomas in Humans Approach With Bevacizumab-IRDye 800CW
ClinicalTrials.gov study NCT03913806. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Neoadjuvant Aliya™ PEF Soft Tissue Ablation With Systemic Therapy in Early-Stage Resectable NSCLC
ClinicalTrials.gov study NCT05583188. IPD Sharing: NO. Countries: 1. Publications: 2.
Palliative Radiotherapy in Symptomatic Pelvic Soft Tissue Tumors
ClinicalTrials.gov study NCT06398314. IPD Sharing: NO. Countries: 1. Publications: 1.
Effects of Recurrent Application of Liquid-PRF on Hard and Soft Tissues
ClinicalTrials.gov study NCT05492357. IPD Sharing: NO. Countries: 1. Publications: 1.
RNASARC - Molecular Screening Program of Soft Tissue Sarcomas With Complex Genomic Profile to Detect NTRK1/2/3, ROS1 or ALK Gene Fusions.
ClinicalTrials.gov study NCT03375437. IPD Sharing: Not stated. Countries: 1. Publications: 14.
Medial Tab Flap for Soft Tissue Defects of the Leg
ClinicalTrials.gov study NCT05864963. IPD Sharing: NO. Countries: 1. Publications: 16.
Ph II Nintedanib vs. Ifosfamide in Soft Tissue Sarcoma
ClinicalTrials.gov study NCT02808247. IPD Sharing: NO. Countries: 7. Publications: 1.
The Severe Soft Tissue Bleeding Study
ClinicalTrials.gov study NCT00977925. IPD Sharing: Not stated. Countries: 4. Publications: 3.
Hyperthermia and Proton Therapy in Unresectable Soft Tissue Sarcoma
ClinicalTrials.gov study NCT01904565. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Molecular Profiling of Advanced Soft-tissue Sarcomas
ClinicalTrials.gov study NCT03784014. IPD Sharing: YES. Countries: 1. Publications: 3.
SBRT Treatment for Lung Metastasis From Soft Tissue Sarcoma
ClinicalTrials.gov study NCT02561559. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.