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468 results for “Spikes”
The Spike Protein of SARS-CoV-2 Impairs Lipid Metabolism and Increases Susceptibility to Lipotoxicity: Implication for a Role of Nrf2
<p>Original figures for the following publication: </p> <p>The Spike Protein of SARS-CoV-2 Impairs Lipid Metabolism and Increases Susceptibility to Lipotoxicity: Implication for a Role of Nrf2</p> <table align="left"> <tbody> <tr> <td> <p><em>Cells </em><strong>2022</strong>, <em>11</em>, x. https://doi.org/10.3390/xxxxx</p> </td> </tr> </tbody> </table>
A synchronous spectrofluorometric technique for simultaneous detection of alfuzosin and tadalafil: Applied to tablets and spiked biological samples
<p>A facile, accurate, eco-friendly, and sensitive spectrofluorometric method was evolved to assay alfuzosin hydrochloride (AFH) and tadalafil (TDF) in different matrices. Such a co-administered combination is clinically used for the treatment of lower urinary tract symptoms. Both compounds are characterized by their native fluorescence spectra upon excitation at specific wavelengths. Their characteristic fluorescence spectra were utilized for sensitive assay of the studied analytes in tablets and human biological samples. The assay principle is based on first-order synchronous spectrofluorometric scan using Dλ = 60 nm in which AFH peaks were recorded at 366 nm. Meanwhile, TDF measurements were recorded at 293 nm in the same scans without overlap with AFH spectra. Recent analytical chemistry trends were implemented to lessen occupational and environmental perils, utilizing ethanol as a diluting solvent for method optimization and application. Linearity ranges were 5.0–90.0 and 10.0–100.0 ng. <span>mL⁻1</span> for AFH and TDF, respectively in their raw materials with average % recoveries of 100.44 % and 99.73 % in raw materials, 100.15 % and 100.20 % in spiked plasma, and 97.14 % and 99.99 % in spiked urine. The proposed method was successfully applied to Prostetrol® and Starkoprex® commercial tablets with no interference with common tablet additives.</p>
Increased wheat price spikes and larger economic inequality with 2oC global warming
<p>This is data for the paper "Increased wheat price spikes and larger economic inequality with 2oC global warming" published on One Earth. </p>
FIGURE 4 in Systematics of New Guinea treefrogs (Litoria: Pelodryadidae) with erectile rostral spikes: an extended description of Litoria pronimia and a new species from the Foja Mountains
FIGURE 4. Litoria pinocchio sp. nov. holotype (MZB amph.15094) in preservative: A) dorsal view, B) ventral view. Scale = 10 mm.
FIGURE 1. Papuan Litoria with a in Systematics of New Guinea treefrogs (Litoria: Pelodryadidae) with erectile rostral spikes: an extended description of Litoria pronimia and a new species from the Foja Mountains
FIGURE 1. Papuan Litoria with a rostral spike: A) Litoria pronimia, male, Tabubil, PNG, with spike erect; B) Litoria pronimia, male, Tabubil, PNG, with spike not erect; C) Litoria pronimia, male Kikori River Basin, PNG; D) Litoria pronimia, male, Timika, Indonesia; E) Litoria havina, male, Kikori River Basin, PNG; F) Litoria mucro, male, Foja Mountains, Indonesia; G) Litoria prora, male and female, Kikori River Basin; H) Litoria chrisdahli, Wamangu, PNG. Photographs: S. Richards.
FIGURE 2 in Systematics of New Guinea treefrogs (Litoria: Pelodryadidae) with erectile rostral spikes: an extended description of Litoria pronimia and a new species from the Foja Mountains
FIGURE 2. Litoria pronimia in preservative from near the type locality at Tabubil (SAMA R71135–6, 71140) and the Kikori River Basin (SAMA R77131). Photograph by Peter Waddington, Queensland Museum.
FIGURE 5 in Systematics of New Guinea treefrogs (Litoria: Pelodryadidae) with erectile rostral spikes: an extended description of Litoria pronimia and a new species from the Foja Mountains
FIGURE 5. Litoria pinocchio sp. nov. holotype (MZB amph.15094) in life: A) lateral profile with rostral spike moderately erect; B) profile of head; C) frontal view of head; D) lateral view with spike fully erected; and E) colouration of axilla and groin. Photographs: A–D by T. Laman; E by P. Oliver.
FIGURE 3 in Systematics of New Guinea treefrogs (Litoria: Pelodryadidae) with erectile rostral spikes: an extended description of Litoria pronimia and a new species from the Foja Mountains
FIGURE 3. Distribution of Litoria pronimia (squares) across southern New Guinea and Litoria pinocchio sp. nov. in the Foja Mountains (asterisk).
FIGURE 6 in Systematics of New Guinea treefrogs (Litoria: Pelodryadidae) with erectile rostral spikes: an extended description of Litoria pronimia and a new species from the Foja Mountains
FIGURE 6. Habitat of Litoria pinocchio sp. nov. in lower montane forest (1250 m a.s.l.) in the Foja Mountains. Photograph T. Laman.
Spike recordings from micro-electrocorticographic arrays
<p><strong>General description:</strong> This is the sample micro-ECoG recording for a sample animal (rat) for a sample session. Electrode dimensions are 30x30μm, with center-to-center pitch of 400 μm. The array was microfabricated on a flexible, ultra-thin parylene C substrate (4 μm). The array was placed over the rat's right M1 cortex (2✕2 cm craniotomy, with lower left corner 1 mm anterior and lateral to the bregma).</p> <p>The rat performs spontaneous navigation within a rectangular test arena, with simultaneous recording through the micro-ECoG array.</p> <p><strong>File type: </strong>Pickle file containing a <em>Python</em> dictionary object.</p> <p><strong>Variable names: </strong><em>N: </em>number of sorted units, <em>k:</em> number of samples, <em>t:</em> number of time steps</p> <ul> <li><strong>unit identifier</strong>: <em>uN (e.g., u0,</em> u1, ... u58) <ul> <li><strong>spike_timing_ms</strong> - <em>k</em> x 1: spike timing in milliseconds (with respect to spike troughs)</li> <li><strong>spike_waveform_mean </strong>- <em>t</em> x 1: mean spike waveform</li> <li><strong>wave_form </strong>-<strong> </strong><em>t</em> x <em>k</em>: individual spike waveforms for each spike, units in microvolts. 100ms per time step (-1 ms and +3 ms around spike trough)</li> <li><strong>rat</strong>: animal identifier</li> <li><strong>ch</strong>: electrode channel</li> <li><strong>unit</strong>: unit identifier</li> </ul> </li> </ul> <p><strong>Possible uses: </strong>This can be used to compare with other micro-ECoG recordings. The spikes likely arise from layer I neurons, which lie in proximity to the surface recording microelectrodes.</p> <p><strong>Contact information: </strong>For any queries, please direct to Yu Tung Lo (Jack) <jacklo@nus.edu.sg>.</p>
Datasets for "Detecting rhythmic spiking through the power spectra of point process model residuals"
<p>This repository contains synthetic and empirical datasets that were analyzed in the preprint "Detecting rhythmic spiking through the power spectra of point process model residuals."</p> <p>Relative to the previous version (1.0.0), this new version (1.0.1) only entails changes in the naming of some folders, and the text of an explanatory text file. The changes reflect the reordering of the figures in the newest version of the manuscript.</p>
Light-Induced Spiking Response in Proteinoid-Actin-Kombucha System
<p>Data for the paper: 'Light-Induced Spiking Response in Proteinoid-Actin-Kombucha System'</p>
Mean and variance of spike counts for area MT neurons in awake and anesthetized subjects
<p>These data are the means and variance of spike counts in an analysis window beginning at motion onset of the visual stimulus, within the receptive field of MT neurons recorded in anesthetized or alert non-human primates. Dot motion was presented in a range of motion directions, with 0 degrees being the preferred direction of each cell. The tuning of the variability in the response and a model accounting for these state-dependent changes is in press at PLoS Computational Biology, along with more details on the data collection and analysis. A preprint is available at: https://arxiv.org/abs/1710.10548</p> <p>These data consist of a MatLab data file with two saved data structures, ‘units’ and ‘autocorrelation’. <br> <br> ‘units’ is an 80-element structure, one entry for each recorded extracellular single unit (putative neuron) in the recording with the following fields:<br> ‘state’ indicates whether the subject was anesthetized or alert during the recording<br> ‘stimDir’ is the direction of motion, in degrees, of the moving dot stimulus<br> ‘latency’ is the latency, in milliseconds, to the response onset<br> ‘latAlign’ are the spike counts and variance in a 150ms window beginning at response onset<br> ‘stimAligned’ are the spike counts and variance in a 250ms window beginning at motion onset<br> ‘MI’ is the mutual information between motion directions between +/- 90 degrees and the cumulative spike counts at a range of time points since motion onset, given in MI_time_vec. The mutual information quantity is extrapolated to the infinite data size limit via quadratic extrapolation.<br> 'MI_time_vec' is a vector of times (in milliseconds) since motion onset used in the information calculation</p> <p><br> ‘autocorrelation’ is a scalar structure containing the fields:<br> 'alert' is the average autocorrelation (range +/- 1) of the spike counts (analyzed in a 2ms window and smoothed over 5 bins) in the alert units during presentation of the null (no dot motion) stimulus<br> 'anesthetized' is the average autocorrelation (computed as for the alert units) of the anesthetized units during presentation of the null stimulus<br> 'timePoints' are the time point shifts in milliseconds corresponding to the calculated autocorrelations in 'alert' and 'anesthetized'</p>
FIGURE 2. Tillandsia chalcatzingensis A. Inflorescence. B. Spike and detail with a flower. C. Floral bract. D. Flower. E. Petals. F. Androecium and gynoecium. Photos. R. Cerros and A in Tillandsia chalcatzingensis, a new species from the state of Morelos, Mexico
FIGURE 2. Tillandsia chalcatzingensis A. Inflorescence. B. Spike and detail with a flower. C. Floral bract. D. Flower. E. Petals. F. Androecium and gynoecium. Photos. R. Cerros and A. Espejo.
FIGURE 1. Carex procumbens, A. Habit, B. Inflorescence, C. Lateral pistillate spike, D. Staminate glume, E. Pistillate glume, F. Terminal staminate spike, G in Carex procumbens (Carex sect. Rhomboidales, Cyperaceae), a new species from Hainan, China
FIGURE 1. Carex procumbens, A. Habit, B. Inflorescence, C. Lateral pistillate spike, D. Staminate glume, E. Pistillate glume, F. Terminal staminate spike, G. Stigmas. Scale bars=1 mm. Photographs by Hu-Biao YANG.
FIGURE 3. Carex procumbens. A. Habit. B. Inflorescence. C. Lateral pistillate spikes. D. Terminal staminate spike. E. Pistillate glume. F. Staminate glume. G. Periginia. H in Carex procumbens (Carex sect. Rhomboidales, Cyperaceae), a new species from Hainan, China
FIGURE 3. Carex procumbens. A. Habit. B. Inflorescence. C. Lateral pistillate spikes. D. Terminal staminate spike. E. Pistillate glume. F. Staminate glume. G. Periginia. H. Nutlet. Drawn by Yu-xi Zhu based on Yang Hubiao 20140228001 (holotype, IBSC!).
FIGURE 4. Limonium korakonisicum R.Artelari & Valli. A. Lower leaf surface. B. Spike. C. Outer bract. D. Middle bract. E. Inner bract. F. Calyx. G in Limonium korakonisicum (Plumbaginaceae), a new species from Zakynthos Island (Ionian Islands, Greece)
FIGURE 4. Limonium korakonisicum R.Artelari & Valli. A. Lower leaf surface. B. Spike. C. Outer bract. D. Middle bract. E. Inner bract. F. Calyx. G. Calyx lobes.
FIGURE 3. Carex concava. A. Habit. B. Terminal staminate spike. C. Lateral pistillate spike. D. Staminate glume. E. Pistillate glume. F. Perigynium. G in Carex concava (Carex sect. Rhomboidales, Cyperaceae), a new species from Hainan, China
FIGURE 3. Carex concava. A. Habit. B. Terminal staminate spike. C. Lateral pistillate spike. D. Staminate glume. E. Pistillate glume. F. Perigynium. G. Nutlet. Drawn by Yu-xi Zhu.
FIGURE 1. Carex concava, A. Inflorescence. B. Habit. C. Lateral pistillate spike. D. Terminal staminate spike. E. Perigynium with stigmas. F. Pistillate glume. G. Staminate glume. Scale A, B, D in Carex concava (Carex sect. Rhomboidales, Cyperaceae), a new species from Hainan, China
FIGURE 1. Carex concava, A. Inflorescence. B. Habit. C. Lateral pistillate spike. D. Terminal staminate spike. E. Perigynium with stigmas. F. Pistillate glume. G. Staminate glume. Scale A, B, D bars=1 cm; E, F, G bars=1 mm. Photographs by Hu-Biao YANG (Apr. 15th, 2014).
FIGURE 8. Acanthopsis insuenta. A & B. Habit. C & D in Taxonomic notes on Acanthopsis (Acanthaceae, tribe Acantheae): the group with semi-dense spikes and 5-fid bracts
FIGURE 8. Acanthopsis insuenta. A & B. Habit. C & D. Leaf indumentum (abaxial). E & F. E &F. Bract. G. Calyx. H. Corolla (lobes lilac; throat lemon-yellow). I. Glandular hairs at base of style. J. Capsule. K. Capsule with seed. Vouchers: C–K = Steyn 1805 (PRE). Photographed by: H.M. Steyn (A–K).
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.