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435 results for “Sterilization”
Data from: Why is sterility virulence most common in sexually transmitted infections? examining the role of epidemiology
Sterility virulence, or the reduction in host fecundity due to infection, occurs in many host-pathogen systems. Notably, sterility virulence is more common for sexually-transmitted infections (STIs) than for directly-transmitted pathogens, while other forms of virulence tend to be limited in STIs. This has led to the suggestion that sterility virulence may have an adaptive explanation. By focusing upon finite population models, we show that the observed patterns of sterility virulence can be explained by consideration of the epidemiological differences between STIs and directly-transmitted pathogens. In particular, when pathogen transmission is predominantly density-invariant (as for STIs), and mortality is density-dependent, sterility virulence can be favoured by demographic stochasticity, whereas if pathogen transmission is predominantly density-dependent, as is common for most directly-transmitted pathogens, sterility virulence is disfavoured. We show these conclusions can hold even if there is a weak selective advantage to sterilizing.
Data from: Dissecting the genetic architecture of F1 hybrid sterility in house mice
Hybrid sterility as a postzygotic reproductive isolation mechanism has been studied for over 80 years, yet the first identifications of hybrid sterility genes in Drosophila and mouse are quite recent. To study the genetic architecture of F_1 hybrid sterility between young subspecies of house mouse Mus m. domesticus and Mus m. musculus we conducted QTL analysis of a backcross between inbred strains representing these two subspecies and probed the role of individual chromosomes in hybrid sterility using the inter-subspecific chromosome substitution strains. We provide direct evidence that the asymmetry in male infertility between reciprocal crosses is conferred by the middle region of Mus m. musculus Chr X, thus excluding other potential candidates such as Y, imprinted genes, and mitochondrial DNA. QTL analysis identified strong hybrid sterility loci on Chr 17 and Chr X and predicted a set of interchangeable autosomal loci, a subset of which is sufficient to activate the Dobzhansky-Muller incompatibility of the strong loci. Overall, our results indicate the oligogenic nature of F_1 hybrid sterility, which should be amenable to reconstruction by proper combination of chromosome substitution strains. Such prefabricated model system should help to uncover the gene networks and molecular mechanisms underlying hybrid sterility.
Data from: Genetics of hybrid male sterility among strains and species in the Drosophila pseudoobscura species group
Taxa in the early stages of speciation may bear intraspecific allelic variation at loci conferring barrier traits in hybrids such as hybrid sterility. Additionally, hybridization may spread alleles that confer barrier traits to other taxa. Historically, few studies examine within- and between-species variation at loci conferring reproductive isolation. Here, we test for allelic variation within Drosophila persimilis and within the Bogota subspecies of D. pseudoobscura at regions previously shown to contribute to hybrid male sterility. We also test whether D. persimilis and the USA subspecies of D. pseudoobscura share an allele conferring hybrid sterility in a D. pseudoobscura bogotana genetic background. All loci conferred similar hybrid sterility effects across all strains studied, though we detected some statistically significant quantitative effect variation among D. persimilis alleles of some hybrid incompatibility QTLs. We also detected allelism between D. persimilis and D. pseudoobscura USA at a 2nd chromosome hybrid sterility QTL. We hypothesize that either the QTL is ancestral in D. persimilis and D. pseudoobscura USA and lost in D. pseudoobscura bogotana, or gene flow transferred the QTL from D. persimilis to D. pseudoobscura USA. We discuss our findings in the context of population features that may contribute to variation in hybrid incompatibilities.
Raw data for measuring health risk of heavy metals in Pasteurized and sterilized Milk across the Globe
Open the record for dataset details and reuse information.
Table S1. Mean longevity of gamma sterilized male Ae. aegypti post-treatments
<p>Table S1 showed the mean longevity of gamma sterilized male Ae. aegypti post-treatments</p>
Intramuscular prime/intranasal boost vaccination to induce sterilizing immunity against influenza A virus infection
<p>Primary data of manuscript </p>
Inhibition of Sterile Inflammation by Digoxin
ClinicalTrials.gov study NCT03559868. IPD Sharing: NO. Countries: 1. Publications: 0.
Opportunistic Salpingectomy for Permanent Sterilization at the Time of Cesarean Delivery
ClinicalTrials.gov study NCT03135431. IPD Sharing: NO. Countries: 1. Publications: 0.
Comparison of Results of Different Surgical Techniques Used in Female Tubal Sterilization
ClinicalTrials.gov study NCT04332120. IPD Sharing: UNDECIDED. Countries: 0. Publications: 4.
Sterile Single-use vs Reused Polyvinylchloride Catheter For Intermittent Catheterization In Neurogenic Bladder
ClinicalTrials.gov study NCT03424499. IPD Sharing: NO. Countries: 0. Publications: 19.
Study of Personalized Sterile Humidification Device for Mucositis in Head and Neck Cancer Patients
ClinicalTrials.gov study NCT01930435. IPD Sharing: YES. Countries: 1. Publications: 0.
Study of Excretion Balance and Pharmacokinetics of [14C]-Sodium Valproate (3.7 MBq) in Healthy Postmenopausal or Permanently Sterile Female Subjects
ClinicalTrials.gov study NCT03681158. IPD Sharing: YES. Countries: 1. Publications: 0.
Clinical and Radiographic Evaluation of the Synergistic Effect of Nano Silver Particles and Calcium Hydroxide Versus Triple Antibiotic Paste as Antibacterial Agents for Lesion Sterilization and Tissue
ClinicalTrials.gov study NCT05681221. IPD Sharing: Not stated. Countries: 0. Publications: 5.
Pharmacokinetic Study of ADVATE Reconstituted in 2 mL Sterile Water for Injection
ClinicalTrials.gov study NCT00952822. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Cheetah - Sterile Glove and Clean Instrument Change at the Time of Wound Closure to Reduce Surgical Site Infection
ClinicalTrials.gov study NCT03980652. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Study to Assess Outcomes in Women Undergoing Either Hysteroscopic Sterilization (Essure®) or Laparoscopic Tubal Sterilization
ClinicalTrials.gov study NCT03127722. IPD Sharing: NO. Countries: 1. Publications: 0.
Nitrous Oxide for Pain Management During In-office Transcervical Sterilization
ClinicalTrials.gov study NCT02312739. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Safety & Efficacy Study of the Adiana System for Women Who Desire Permanent Birth Control (Sterilization)
ClinicalTrials.gov study NCT00737061. IPD Sharing: Not stated. Countries: 3. Publications: 0.
3Mixtatin Versus Modified 3Mix-MP in Lesion Sterilization and Tissue Repair for Treatment of Necrotic Primary Molars
ClinicalTrials.gov study NCT05677945. IPD Sharing: NO. Countries: 0. Publications: 7.
A Safety Study of of AG-920 Sterile Topical Ophthalmic Solution
ClinicalTrials.gov study NCT05501860. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.