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269 results for “THaWS”
Hepatic RNA sequence in male mice offspring conceived by in-vitro Fertilization and Frozen-thawed Embryo Transfer
GEO Series GSE164819. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Data from: Indices of immune function used by ecologists are mostly unaffected by repeated freeze-thaw cycles and methodological deviations
Background: Over the past couple of decades, measuring immunological parameters has become widespread in studies of ecology and evolution. A combination of different immunological indices is useful for quantifying different parts of the immune system and comprehensively assessing immune function. Running multiple immune assays usually requires samples to be repeatedly thawed and re-frozen. There is some evidence that repeated freezing and thawing can affect assay results, but this has never been comprehensively studied in some common ecological immunology assays. We tested the effect of multiple (1, 2, 3, 4, 5, 10) freeze-thaw cycles on the results of four commonly used immunological assays: haemolysis-haemagglutination titres, haptoglobin concentration, bacterial killing capacity and total immunoglobulins (IgY). We tested five different bird species from four different bird orders (Passeriformes, Columbiformes, Charadriiformes and Galliformes), and we included both captive and free-living individuals. In addition, we tested for haptoglobin concentrations and the haemolysis-haemagglutination assay if re-analysing samples 1 year apart led to different results. For the haemolysis-haemagglutination assay we also tested two different sources of rabbit blood, and we compared untreated microtitre plates with plates that were "blocked" to prevent nonspecific interactions between the plate and assay reagents. Results: Repeated freezing and thawing of plasma had no effect on lysis titres, haptoglobin concentrations, bacterial killing capacity, or total immunoglobulin levels. Agglutination titres were unaffected by up to five cycles but were lower after ten freeze-thaw cycles. For the haemolysis-haemagglutination assay and haptoglobin concentrations, re-analysing samples 1 year apart yielded highly correlated data. For the haemolysis haemagglutination assay,thesourceofrabbit blood did not influence the results, and the untreated vs. blocked plates differed slightly overall, but at the individual level assay results were highly correlated. Using different rabbit blood sources or different types of microtitre plates yielded highly correlated data.Conclusions: Our data suggest that repeated freeze-thaw cycles do not impair assay results to the point of influencing ecological or evolutionary conclusions. Plasma samples can be safely stored in one tube and thawed repeatedly for different assays. Nevertheless, we recommend consistent treatment of samples in terms of freeze-thaw cycles or other laboratory treatments to minimize the potential for introducing a systematic bias.
Safety and Efficacy of Freezing and Thawing of Human Eggs in Assisted Reproductive Technology
ClinicalTrials.gov study NCT00451009. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Oocyte Cryopreservation: Evaluation of an Oocyte Freezing and Thawing Technique
ClinicalTrials.gov study NCT00713869. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Frozen-thawed Embryo Transfers and Hormone Substitution on Thrombotic Risk Markers
ClinicalTrials.gov study NCT04359576. IPD Sharing: NO. Countries: 1. Publications: 0.
Comparison of Thawing Embryos in Advance and on the Day of Transfer on Pregnancy Outcomes in FET Cycle
ClinicalTrials.gov study NCT04455191. IPD Sharing: Not stated. Countries: 1. Publications: 0.
hCG Supplementation in Frozen-Thawed Embryo Transfer Cycle
ClinicalTrials.gov study NCT00398229. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Reduced Oestrogen Dosage to Improve the Outcome of Frozen-thawed Embryo Transfer
ClinicalTrials.gov study NCT05545592. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Serum Progesterone on the Day of Thawed Embryo Transfer and Pregnancy Rate After an Artificial Endometrial Preparation
ClinicalTrials.gov study NCT04278508. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Oral Dydrogesterone vs. Micronized Vaginal Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer Cycles
ClinicalTrials.gov study NCT04124913. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Artificial Endometrial Preparation for Frozen Thawed Embryo Transfer Applying Either Endometrin or Utrogestan
ClinicalTrials.gov study NCT00345306. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of Vaginal Sildenafil Citrate on Endometrial Preparation and Outcome in Frozen Thawed Embryo Transfer Cycles
ClinicalTrials.gov study NCT03854175. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Effect of Low Molecular Weight Heparin in Freeze-thaw Embryo Transfer Cycles in Women With Recurrent Implantation Failure
ClinicalTrials.gov study NCT06991530. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Adding Sildenafil to Protocol of Endometrial Preparation in Outcome of Frozen-thawed Embryo Transfer Cycles
ClinicalTrials.gov study NCT01668446. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Cryopreserved-thawed Embryo Transfer With or Without Gonadotropin Releasing Hormone Agonist
ClinicalTrials.gov study NCT02736032. IPD Sharing: YES. Countries: 1. Publications: 0.
Subcutaneous Progesterone in Frozen- Thawed Single Euploid Blastocyst Transfer.
ClinicalTrials.gov study NCT04549116. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Oral Dydrogesterone vs. Vaginal Micronized Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer
ClinicalTrials.gov study NCT03832699. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Advantages of Early Intrauterine Transfer of "Blank" Culture Medium Prior to 1st or 2nd Transfer of Thawed Embryo(s).
ClinicalTrials.gov study NCT06177613. IPD Sharing: NO. Countries: 2. Publications: 0.
Optimal Length of Progesterone Supplementation Before the Transfer of Cryopreserved(Frozen)-Thawed Embryos in an Artificial Cycle With Exogenous Estrogen and Progesterone.
ClinicalTrials.gov study NCT02032797. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effect of GnRH Administration During Luteal Support in Frozen-thawed Transfer Cycles
ClinicalTrials.gov study NCT01933009. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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