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540
datasets available to search
ShareScore release 0.9.0
Dataset results
540 results for “data normalization”
Data from: Filamentation and restoration of normal growth in Escherichia coli using a combined CRISPRi sgRNA/antisense RNA approach
CRISPR interference (CRISPRi) using dCas9-sgRNA is a powerful tool for the exploration and manipulation of gene functions. Here we quantify the reversible switching of a central process of the bacterial cell cycle by CRISPRi and an antisense RNA mechanism. Reversible induction of filamentous growth in E. coli has been recently demonstrated by controlling the expression levels of the bacterial cell division proteins FtsZ/FtsA via CRISPRi. If FtsZ falls below a critical level, cells cannot divide. However, the cells remain metabolically active and continue with DNA replication. We surmised that this makes them amenable to an inducible antisense RNA strategy to counteract FtsZ inhibition. We show that both static and inducible thresholds can adjust the characteristics of the switching process. Combining bulk data with single cell measurements, we characterize the efficiency of the switching process. Successful restoration of division is found to occur faster in the presence of antisense sgRNAs than upon simple termination of CRISPRi induction.
The Most Demanding Match Periods: Should GPS Data be Normalized
ClinicalTrials.gov study NCT07321496. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
A Study to Evaluate Endoflip Normal Ranges Data in Healthy Volunteers
ClinicalTrials.gov study NCT04809883. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Wideband Acoustic Immittance Data in Thai Normal Hearing and Conductive Hearing Loss Adults
ClinicalTrials.gov study NCT06251817. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Data Collection of Normal Tissue Toxicity for Proton Therapy for Pediatrics
ClinicalTrials.gov study NCT01502150. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ATAC-Seq Data of Adipose Stem Cells from Subcutaneouse Adipose Tissue of Normal-Weight Polycystic Ovary Syndrome Women Undergoing Adipogenesis in vitro
GEO Series GSE156140. Homo sapiens. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Expression data from leaves of rice plants overexpressing the OsCPK4 gene and control plants(empty vector) in normal conditions
GEO Series GSE52353. Oryza sativa Japonica Group; Oryza sativa. 24 samples. Type: Expression profiling by array.
iPSC data for the paper "Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mouse model"
GEO Series GSE285209. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Expression data from Methionine normal or deprived culture glioblastoma cell line U251
GEO Series GSE282194. Homo sapiens. 6 samples. Type: Non-coding RNA profiling by array.
Gene expression data from zebrafish SHH medulloblastoma brains and normal brains.
GEO Series GSE242897. Danio rerio. 9 samples. Type: Expression profiling by high throughput sequencing.
scRNASeq data of CD45+CD3-CD19- and keratinocytes in normal and HS skin
GEO Series GSE155850. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
miRNA sequencing data of normal glucose tolerant (NGT) and gestational diabetes (GDM) pregnant women
GEO Series GSE218696. Homo sapiens. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Data from: Gonadotropin-releasing hormone receptor (Gnrhr) gene knock out: normal growth and development of sensory, motor and spatial orientation behavior but altered metabolism in neonatal and prepubertal mice
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Data from: Monoallelic chromatin conformation flanking long-range silenced domains in cancer-derived and normal cells
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Data from: Benefits of normal body mass index on physical fitness: a cross-sectional study among children and adolescents in Xinjiang Uyghur Autonomous Region, China
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Data from: Use of normalized difference vegetation index to assess N status and predict grain yield in rice
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Data from: Prognosis of chronic kidney disease with normal-range proteinuria: The CKD-ROUTE study
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Data from: Filamentation and restoration of normal growth in Escherichia coli using a combined CRISPRi sgRNA/antisense RNA approach
Open the record for dataset details and reuse information.
SNP data from 125 hepatocellular carcinomas and 112 paired normal samples
GEO Series GSE32649. Homo sapiens. 237 samples. Type: Genome variation profiling by SNP array.
Global mouse gene expression data from NUP98-NSD1/FLT3-ITD AML samples and Normal Wild Type whole bone marrow and Normal Wild Type lineage negative bone marrow samples assessed by Bulk RNA-Seq.
GEO Series GSE229501. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.