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346 results for “functional integration”
Figure 6 from: Datry T, Allen D, Argelich R, Barquin J, Bonada N, Boulton A, Branger F, Cai Y, Cañedo-Argüelles M, Cid N, Csabai Z, Dallimer M, de Araújo JC, Declerck S, Dekker T, Döll P, Encalada A, Forcellini M, Foulquier A, Heino J, Jabot F, Keszler P, Kopperoinen L, Kralisch S, Künne A, Lamouroux N, Lauvernet C, Lehtoranta V, Loskotová B, Marcé R, Martin Ortega J, Matauschek C, Miliša M, Mogyorósi S, Moya N, Müller Schmied H, Munné A, Munoz F, Mykrä H, Pal I, Paloniemi R, Pařil P, Pengal P, Pernecker B, Polášek M, Rezende C, Sabater S, Sarremejane R, Schmidt G, Senerpont Domis L, Singer G, Suárez E, Talluto M, Teurlincx S, Trautmann T, Truchy A, Tyllianakis E, Väisänen S, Varumo L, Vidal J-P, Vilmi A, Vinyoles D (2021) Securing Biodiversity, Functional Integrity, and Ecosystem Services in Drying River Networks (DRYvER). Research Ideas and Outcomes 7: e77750. https://doi.org/10.3897/rio.7.e77750
Figure 6 DRYvER partners' complementarity.
Figure 5 from: Datry T, Allen D, Argelich R, Barquin J, Bonada N, Boulton A, Branger F, Cai Y, Cañedo-Argüelles M, Cid N, Csabai Z, Dallimer M, de Araújo JC, Declerck S, Dekker T, Döll P, Encalada A, Forcellini M, Foulquier A, Heino J, Jabot F, Keszler P, Kopperoinen L, Kralisch S, Künne A, Lamouroux N, Lauvernet C, Lehtoranta V, Loskotová B, Marcé R, Martin Ortega J, Matauschek C, Miliša M, Mogyorósi S, Moya N, Müller Schmied H, Munné A, Munoz F, Mykrä H, Pal I, Paloniemi R, Pařil P, Pengal P, Pernecker B, Polášek M, Rezende C, Sabater S, Sarremejane R, Schmidt G, Senerpont Domis L, Singer G, Suárez E, Talluto M, Teurlincx S, Trautmann T, Truchy A, Tyllianakis E, Väisänen S, Varumo L, Vidal J-P, Vilmi A, Vinyoles D (2021) Securing Biodiversity, Functional Integrity, and Ecosystem Services in Drying River Networks (DRYvER). Research Ideas and Outcomes 7: e77750. https://doi.org/10.3897/rio.7.e77750
Figure 5 DRYvER management structure.
Multi-Omic Integration by Machine Learning (MIMaL) Reveals Protein-Metabolite Connections and New Gene Functions
<p>Metabolomics and proteomics generate large, complex datasets that reflect the state of a biological system. Multi-omics is the integration of these disparate methods and data to gain a clearer picture of the biological state. Multi-omic studies of the proteome and metabolome are becoming more common as mass spectrometry technology continues to be democratized. However, knowledge extraction through integration of these data remains challenging. Here we show that connections between these omic layers can be discovered through a combination of machine learning and model interpretation. We find that SHAP values connecting proteins to metabolites are valid experimentally, and reveal also largely new connections. Further, clustering the magnitudes of protein control over all metabolites enabled prediction of gene five gene functions, each of which was validated experimentally. We accurately predicted that two uncharacterized genes in yeast modulate mitochondrial translation, <em>YJR120W</em> and <em>YLD157C</em>.We also predict and validate functions for several incompletely characterized genes, including <em>SDH9</em>, <em>ISC1</em>, and <em>FMP52</em>. Our work demonstrates that multi-omic analysis with machine learning (MIMaL) is a new lens that reveals new insight from multi-omic data that would not be possible using any omic layer alone.</p>
The Synergistic Effects of Integrated Neuromuscular Inhibition Technique and Dry Cupping Therapy on Pain Modulation and Functional Recovery on Myofascial Trigger Points of Upper Trapezius
ClinicalTrials.gov study NCT07027644. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effect of Transaortic Valve Replacement on the Endothelial Integrity and Function
ClinicalTrials.gov study NCT01993485. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Soft Tissue Detection on MRI, Cone Beam CT and Fan Beam CT and Integration of Functional MRI
ClinicalTrials.gov study NCT01859338. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Integrated Life Skill Training and Executive Function Strategies in Children With ASD
ClinicalTrials.gov study NCT05829577. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Integrated Cueing on Functional Transfers in Chronic Stroke Survivors
ClinicalTrials.gov study NCT04498429. IPD Sharing: NO. Countries: 1. Publications: 0.
The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain
ClinicalTrials.gov study NCT05701982. IPD Sharing: YES. Countries: 1. Publications: 0.
Prospective Neurobehavioral Functions in Newly-diagnosed Patients With Primary CNS Lymphoma Treated With Hyperfractionated Conformal Whole-brain Radiation Therapy Plus Simultaneous Integrated Boost
ClinicalTrials.gov study NCT04006561. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Executive Function in Preterm Born Children: An Integrative Approach From Genetics to Brain Function
ClinicalTrials.gov study NCT01615523. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Integrated CBT to Improve Functioning in Veterans With Anxiety and Substance Use
ClinicalTrials.gov study NCT04871100. IPD Sharing: NO. Countries: 1. Publications: 3.
Evaluation of the Effect of Liposomal L-Arg and Vit C Integration on Mitochondrial Function in Patients With Heart Failure
ClinicalTrials.gov study NCT06044194. IPD Sharing: NO. Countries: 1. Publications: 0.
Lifestyle Integrated Functional Exercise for People With Dementia: a Home-based Physical Activity Program
ClinicalTrials.gov study NCT03757806. IPD Sharing: NO. Countries: 1. Publications: 0.
Temporary Epicardial Pace Wire With Integrated Sensor for Continuous Postoperative Monitoring of Myocardial Function
ClinicalTrials.gov study NCT04886934. IPD Sharing: NO. Countries: 1. Publications: 0.
Integrating Ketamine Effects on Neuronal Molecular Signatures and the Brain Functional and Structural Connectome
ClinicalTrials.gov study NCT06698848. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Integrated Genetic and Functional Analysis of the Influence of Menstrual Hygiene Products on Female Health
ClinicalTrials.gov study NCT06519799. IPD Sharing: NO. Countries: 1. Publications: 0.
Sensory Integration Versus Bobath on Hand Function in Hemiplegia
ClinicalTrials.gov study NCT06955247. IPD Sharing: YES. Countries: 1. Publications: 0.
The Effect of Sensory Integration Therapy on Upper Extremity Functions, Trunk Control and Balance in Children With Cerebral Palsy
ClinicalTrials.gov study NCT04802551. IPD Sharing: NO. Countries: 1. Publications: 0.
Integrated Genetic and Functional Analysis of the Female Microbiome in a Flemish Cohort
ClinicalTrials.gov study NCT04319536. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.