Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
418
datasets available to search
ShareScore release 0.9.0
Dataset results
418 results for “prefrontal cortex”
Gender specific transcription regulation in the prefrontal cortex following social defeat stress
GEO Series GSE146845. Mus musculus. 25 samples. Type: Expression profiling by high throughput sequencing.
DNase-seq from dorsolateral prefrontal cortex (ENCSR419KXU)
GEO Series GSE169894. Homo sapiens. 1 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Autism-Related Transcription Factors Underlying the Sex-Specific Effects of Prenatal Bisphenol A Exposure on Transcriptome-Interactome Profiles in the Offspring Prefrontal Cortex
GEO Series GSE229073. Rattus norvegicus. 4 samples. Type: Expression profiling by high throughput sequencing.
Profiling Transcriptomic Alterations in Postmortem Prefrontal Cortex Tissues of Individuals with Alcohol Use Disorders
GEO Series GSE49376. Homo sapiens. 48 samples. Type: Expression profiling by array.
DNase-seq from dorsolateral prefrontal cortex (ENCSR785MXI)
GEO Series GSE170086. Homo sapiens. 1 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
DNase-seq from dorsolateral prefrontal cortex (ENCSR796YOJ)
GEO Series GSE170132. Homo sapiens. 1 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Electrophysiological recordings from: Effects of Acute Stress on the Oscillatory Activity of the Hippocampus-Amygdala-Prefrontal Cortex Network. Merino et al. 2021
<p>Electrophysiological recordings of local field potentials (LFP) from infralimbic cortex (IL), basolateral amygdala (BLA) and dorsal hippocampus (dHPC). These data are collected from urethane-anesthetized rats. </p><p><strong>Abstract:</strong></p><p>Displaying a stress response to threatening stimuli is essential for survival. These reactions must be adjusted to be adaptive. Otherwise, even mental illnesses may develop. Describing the physiological stress response may contribute to distinguishing the abnormal responses that accompany the pathology, which may help to improve the development of both diagnoses and treatments. Recent advances have elucidated many of the processes and structures involved in stress response management; however, there is still much to unravel regarding this phenomenon. The main aim of the present research is to characterize the response of three brain areas deeply involved in the stress response (i.e., to an acute stressful experience). Specifically, the electrophysiological activity of the infralimbic division of the medial prefrontal cortex (IL), the basolateral nucleus of the amygdala (BLA), and the dorsal hippocampus (dHPC) was recorded after the infusion of 0.5 µl of corticosterone-releasing factor into the dorsal raphe nucleus (DRN), a procedure which has been validated as a paradigm to cause acute stress. This procedure induced a delayed reduction in slow waves in the three structures, and an increase in faster oscillations, such as those in theta, beta, and gamma bands. The mutual information at low theta frequencies between the BLA and the IL increased, and the delta and slow wave mutual information decreased. The low theta-mid gamma phase-amplitude coupling increased within BLA, as well as between BLA and IL. This electrical pattern may facilitate the activation of these structures, in response to the stressor, and memory consolidation. </p>
Alterations ion channel expression in prefrontal cortex of a mouse model of schizophrenia
<p>Maternal immune activation (MIA) and juvenile social isolation (SI) are two most prevalent and widely accepted environmental insults that could increase the propensity of psychiatric illnesses. Using a two-hit model, we examined the impact of these two factors on expressions of voltage-gated sodium (Nav) and small conductance calcium-activated potassium (SK) channels in the prefrontal cortex (PFC). We found that MIA-SI significantly increased the expression level of Nav1.2 and SK3 channels that contribute to the somatodendritic potential and the mAHP, respectively. </p>
Neural Effects of Green Tea Extract on Dorsolateral Prefrontal Cortex
ClinicalTrials.gov study NCT01615289. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Probing Homeostatic Plasticity With Priming Theta-burst Stimulation of the Dorsolateral Prefrontal Cortex
ClinicalTrials.gov study NCT04031105. IPD Sharing: NO. Countries: 1. Publications: 0.
Dorsolateral Prefrontal Cortex Transcranial Direct Current and Muscle Fatigue Stimulation on Muscle Fatigue
ClinicalTrials.gov study NCT06389162. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Effects of High-Intensity, Low-Frequency Periodic rTMS Over the Right Dorsolateral Prefrontal Cortex on Cardiac Autonomic Regulation in Women With Recurrent Pregnancy Loss and Anxiety: A Proof-of-Conc
ClinicalTrials.gov study NCT06968026. IPD Sharing: YES. Countries: 1. Publications: 0.
Functional Roles of Dorsolateral Prefrontal Cortex
ClinicalTrials.gov study NCT03882931. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Self-regulation of Prefrontal Cortex During Emotional Cognitive Control in PTSD
ClinicalTrials.gov study NCT04543513. IPD Sharing: NO. Countries: 1. Publications: 0.
Clinical Exploratory Research of Medial Prefrontal Cortex Combined With Dorsolateral Prefrontal Cortex Electrical Stimulation in the Treatment of Alzheimer's Disease
ClinicalTrials.gov study NCT05971030. IPD Sharing: YES. Countries: 1. Publications: 0.
The Effect of rTMS to the Prefrontal Cortex in Alcohol Use Disorder
ClinicalTrials.gov study NCT03809286. IPD Sharing: NO. Countries: 1. Publications: 0.
Neuronavigated Repetitive Transcranial Magnetic Stimulation (nrTMS) of the Dorsolateral Prefrontal and Primary Motor Cortex for the Treatment of Chronic Pain
ClinicalTrials.gov study NCT04934150. IPD Sharing: NO. Countries: 1. Publications: 0.
Transcranial Direct and Alternating Stimulation of the Prefrontal Cortex for Cognitive Improvement in Schizophrenia
ClinicalTrials.gov study NCT05342727. IPD Sharing: NO. Countries: 1. Publications: 0.
Somesthesic Role of the Ventro-lateral Prefrontal Cortex in Speech Motor Learning
ClinicalTrials.gov study NCT04547569. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of Stimulation of Dorsolateral Prefrontal Cortex on Language Control
ClinicalTrials.gov study NCT02289521. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.