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2,227
datasets available to search
ShareScore release 0.9.0
Dataset results
2,227 results for “Tissue expression”
Remodeling of tissue-resident macrophages by MEF2D-expressing cancer precursors primes for liver tumorigenesis [RNA-Seq]
GEO Series GSE278097. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.
Microarray approach to investigate gene expression in human ovarian tissue after xenografting
GEO Series GSE47555. Homo sapiens. 8 samples. Type: Expression profiling by array.
MicroRNA Expression data from formalin-fixed, paraffin-embedded (FFPE) granulosa cell tumour (GCT) tissue samples
GEO Series GSE70026. Homo sapiens; synthetic construct. 10 samples. Type: Non-coding RNA profiling by array.
Gene expression profiles of mesenterial adipose tissue of newborn rats from dams that were either fed a vitamin D adequate (1,000 IU vitamin D/kg diet) or a vitamin D deficient diet (0 IU vitamin D/kg
GEO Series GSE82215. Rattus norvegicus. 6 samples. Type: Expression profiling by array.
Impact of Polymorphisms on Gene Expression and Splicing in Response to Exercise and Diet-induced Weight-loss in Human Skeletal Muscle Tissues
<p>This is the comprehensive datasets pre-intervention and post-intervention in Singapore Adult Metabolism Study-2</p> <p>Including the clinical data, full e/sQTL summary statistics, and significant e/sQTL summary statistics.</p>
Expression data from lung tissue of exsmokers
GEO Series GSE119040. Homo sapiens. 10 samples. Type: Expression profiling by array.
Human skeletal muscle tissue chip autonomous payload reveals changes in fiber type and metabolic gene expression due to spaceflight.
Microphysiological systems provide the opportunity to model accelerated changes at the human tissue level in the extreme space environment. Spaceflight-induced muscle atrophy experienced by astronauts shares similar physiological changes to muscle wasting in older adults, known as sarcopenia. These shared attributes provide a rationale for investigating molecular changes in muscle cells exposed to spaceflight that may mimic the underlying pathophysiology of sarcopenia. We report the results from three-dimensional myobundles derived from muscle biopsies from young and older adults, integrated into an autonomous CubeLab™, and flown to the International Space Station (ISS) aboard SpaceX CRS-21 as part of the NIH/NASA funded Tissue Chips in Space program. Global transcriptomic RNA-Seq analyses comparing the myobundles in space and on the ground revealed downregulation of shared transcripts related to myoblast proliferation and muscle differentiation. The analyses also revealed downregulated differentially expressed gene pathways related to muscle metabolism unique to myobundles derived from the older cohort exposed to the space environment compared to ground controls. Gene classes related to inflammatory pathways were downregulated in flight samples cultured from the younger cohort compared to ground controls. Our muscle tissue chip platform provides an approach to studying the cell autonomous effects of spaceflight on muscle cell biology that may not be appreciated on the whole organ or organism level and sets the stage for continued data collection from muscle tissue chip experimentation in microgravity. We also report on the challenges and opportunities for conducting autonomous tissue-on-chip CubeLab™ payloads on the ISS.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.