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13,621 results for “Biologics”
Biologics repositioning: ml-SOM analysis raw results
<p><strong>Summary</strong></p> <p>This dataset contains raw result files for multiple-layer SOM (ml-SOM) repositioning analysis of infliximab and brodalumab. </p> <p><strong>Infliximab_results.zip</strong> archive contains the results of ml-SOM repositioning analysis of infliximab (T1) as a potential therapeutics for ulcerative colitis (D1), Crohn’s disease (D2), COPD (R1) and sarcoidosis (R2).</p> <p>Data is organized in the archive as follows:</p> <ol> <li>inflixmab_UC_CD_COPD_SARC021018_results+.RData - R data file that contains ml-SOM environment</li> <li>folder "inflixmab_UC_CD_COPD_SARC021018_results+ - Results" - comprises of various PDF and CSV files representing the a ml-SOM analysis results. It also contains the separate layer-level SOM analysis results for all datasets: <ul> <li>folder "1" - SOM analysis of infliximab dataset</li> <li>folder "2" - SOM analysis for ulcerative colitis and Crohn's disease dataset</li> <li>folder "3" - SOM analysis for COPD dataset</li> <li>folder "4" - SOM analysis for sarcoidosis dataset.</li> </ul> </li> </ol> <p><strong>Brodalumab_results.zip</strong> archive contains the results of ml-SOM repositioning analysis of brodalumab (T1) as a potential therapeutics for psoriasis (D1), Crohn’s disease (R1), and systemic juvenile idiopathic arthritis (R2).</p> <p>Data is organized in the archive as follows:</p> <ol> <li>brodalumab_CD_SJIA_301218_results+.RData - R data file that contains ml-SOM environment</li> <li>folder "brodalumab_CD_SJIA_301218_results+ - Results" - comprises of various PDF and CSV files representing the a ml-SOM analysis results. It also contains the separate layer-level SOM analysis results for all datasets: <ul> <li>folder "1" - SOM analysis of brodalumab and psoriasis dataset</li> <li>folder "2" - SOM analysis for Crohn's disease dataset</li> <li>folder "3" - SOM analysis for systemic juvenile idiopathic arthritis dataset</li> </ul> </li> </ol> <p>For detailed instructions on browsing the results and their interpretation please refer to the oposSOM package manual [1], as well as original publications [2-4]. </p> <p><strong>References</strong></p> <ol> <li>Henry Loeffler-Wirth, Hoang Thanh Le and Martin KalcheroposSOM.Comprehensive analysis of transcriptome data. DOI: <a href="https://doi.org/doi:10.18129/B9.bioc.oposSOM">10.18129/B9.bioc.oposSOM</a> </li> <li>Löffler-Wirth H, Kalcher M, Binder H. oposSOM: R-package for high-dimensional portraying of genome-wide expression landscapes on bioconductor.Bioinformatics. 2015 Oct 1;31(19):3225-7. DOI: 10.1093/bioinformatics/btv342. Epub 2015 Jun 10.</li> <li>Wirth H, von Bergen M, Binder H. Mining SOM expression portraits: feature selection and integrating concepts of molecular function. BioData Min. 2012 Oct 8;5(1):18. DOI: 10.1186/1756-0381-5-18.</li> <li>Wirth H, Löffler M, von Bergen M, Binder H. Expression cartography of human tissues using self organizing maps. BMC Bioinformatics. 2011 Jul 27;12:306. DOI: 10.1186/1471-2105-12-306.</li> </ol> <p> </p>
Post-revision data and R Script for Murtagh et al. 'The scent of enrichment: Exploring the effect of odour and biological salience on behaviour during enrichment of kennelled dogs.'
<p>Data and analysis file (written in R studio) for the paper Murtagh et al. 'The scent of enrichment: Exploring the effect of odour and biological salience on behaviour during enrichment of kennelled dogs.' Updated based on reviewer comments and additional analyses requested (master data and analysis filed labelled with 'rev' suffix).</p>
Fig. 3 in Nesting biology of three Megachile (Hymenoptera: Megachilidae) species from Eastern Amazonia, Brazil
Fig. 3. Estimatives of minimum and maximum time development of Megachile bees in SA and APABM.
Fig. 4 in Biology and reproductive capacity of Spodoptera eridania (Cramer) (Lepidoptera, Noctuidae) in different soybean cultivars
Fig. 4. Number of eggs/female of Spodoptera eridania during the oviposition period.
Figure 6 in Biological diversity and seasonal variation of mesozooplankton in the southeastern Black Sea coastal ecosystem
Figure 6. Anchovy production during the sampling period.
Figure 8. S in Reproductive biology of pink cuttlefish Sepia orbignyana in the Aegean Sea (eastern Mediterranean)
Figure 8. S. orbignyana egg diameter distribution percentages for different gonad stages.
Figure 4 in Reproductive biology of pink cuttlefish Sepia orbignyana in the Aegean Sea (eastern Mediterranean)
Figure 4. Bathymetric distribution of the different-sized S. orbignyana in the Aegean Sea.
Figure 6 in Reproductive biology of Acomys cilicicus Spitzenberger, 1978 (Rodentia: Muridae) in Turkey
Figure 6. Suckling process.
Figure 1 in Reproductive biology of Acomys cilicicus Spitzenberger, 1978 (Rodentia: Muridae) in Turkey
Figure 1. Picture of the amniotic membrane stuck to the face and shoulder area.
Figure 4 in Reproductive biology of Acomys cilicicus Spitzenberger, 1978 (Rodentia: Muridae) in Turkey
Figure 4. Molars on the mandible of a newborn offspring.
Figure 3 in Reproductive biology of Acomys cilicicus Spitzenberger, 1978 (Rodentia: Muridae) in Turkey
Figure 3. Mother and newborn offspring after birth.
Figure 5 in Macadamia Felted Coccid, Eriococcus ironsidei: Biology and Life Cycle in Hawaii
Figure 5. Complete life cycles of female and male E. ironsidei.
Figure 1 in Macadamia Felted Coccid, Eriococcus ironsidei: Biology and Life Cycle in Hawaii
Figure 1. Adult female rostrum, indicated by red arrows.
Figure 1 in An investigation on some biological and reproduction characteristics of Eriphia verrucosa (Forskål, 1775) in the South Black Sea (Turkey)
Figure 1. Map of the study area.
Figure 5 in Breeding biology of the red-backed shrike, Lanius collurio, in the Kızılırmak Delta in the north of Turkey
Figure 5. Laying time of the red-backed shrikes.
Figure 2 in Breeding biology of the red-backed shrike, Lanius collurio, in the Kızılırmak Delta in the north of Turkey
Figure 2. Nest plants of the red-backed shrikes (n = 108) in the Kızılırmak Delta during 2011–2012.
Figure 6 in Breeding biology of the red-backed shrike, Lanius collurio, in the Kızılırmak Delta in the north of Turkey
Figure 6. Clutch size distribution of the red-backed shrikes.
Figure 3 in Breeding biology of the red-backed shrike, Lanius collurio, in the Kızılırmak Delta in the north of Turkey
Figure 3. Distribution of the orientations of the red-backed shrike nests in the supporting plants.
Fig. 1 in Biology of Blepyrus clavicornis (Compere) (Hymenoptera: Encyrtidae), a parasitoid of Pseudococcus viburni (Signoret) (Hemiptera: Pseudococcidae)
Fig. 1. (A) Blepyrus clavicornis female and (B) male. Scale: 1 mm.
Figure 1 in The determination some biological parameters of Phenacoccus madeirensis Green (Hemiptera: Pseudococcidae) on vegetable plants
Figure 1. Survival ratio and life table parameters of Phenacoccus madeirensis on Tomato (Hazera).
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OpenNeuro
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