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2,435
datasets available to search
ShareScore release 0.9.0
Dataset results
2,435 results for “Metastasis”
Activating MKL1/SRF pathway to target breast cancer metastasis
GEO Series GSE215150. Homo sapiens; Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing.
ECT2 promotes proliferation and metastasis of esophageal squamous cell carcinoma（ESCC） via Rho-ERK-VEGF/MMP9 signaling pathway
GEO Series GSE138570. Homo sapiens. 9 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
RNA m6A reader IGF2BP3 promotes metastasis of triple-negative breast cancer via SLIT2 repression (MeRIP-Seq)
GEO Series GSE202235. Homo sapiens. 4 samples. Type: Other.
The matricellular protein WISP2 is an endogenous inhibitor of collagen linearization and cancer metastasis
GEO Series GSE152514. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Hypoxia-induced phase separation of ZHX2 drives 3D chromatin remodeling and cancer metastasis (RNA-Seq)
GEO Series GSE260794. Homo sapiens. 45 samples. Type: Expression profiling by high throughput sequencing.
Single-cell chromatin accessible state of paired primary and liver metastasis colorectal cancer cells from PDX cells derived mouse model
GEO Series GSE200813. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
The specific interactions of Bcl9/Bcl9L with b-catenin and Pygopus promote breast cancer growth, invasion and metastasis
GEO Series GSE182404. Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing.
Differential LncRNA expression of 5 primary ovarian tumors and matched metastasis
GEO Series GSE224495. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Neutrophils Resist Ferroptosis and Promote Breast Cancer Metastasis through Aconitate Decarboxylase 1
GEO Series GSE216425. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Cancer-associated fibroblasts promote esophageal carcinogenesis and lung metastasis by CDH11-mediated extracellular matrix environment remodeling [scRNA-Seq]
GEO Series GSE309392. Homo sapiens. 23 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Metastasis-directed stereotactic body radiation therapy in the management of oligometastatic head and neck cancer"
<p>This record contains raw data related to article "Metastasis-directed stereotactic body radiation therapy in the management of oligometastatic head and neck cancer"</p> <p><strong>Introduction: </strong>Recently major efforts have been made to define the oligometastatic setting, but for head and neck cancer (HNC) limited data are available. We aimed to evaluate outcome of oligometastatic HNC treated with Stereotactic body radiotherapy (SBRT) as metastasis-directed therapy.</p> <p><strong>Materials and methods: </strong>We analyzed patients treated with SBRT on a maximum of five oligometastases from HNC, in up to two organs. Concomitant treatment was allowed. End points were toxicity, local control of treated metastases (LC), progression-free survival (PFS) and overall survival (OS).</p> <p><strong>Results: </strong>48 consecutive patients and 71 lesions were treated. With a follow-up of 20.2 months, most common primary tumors were larynx (29.2%) and salivary glands (29.2%), while common site of metastases was lung (59.1%). Median dose was 48 Gy (21-75) in 3-8 fractions. Treatment was well tolerated, with two patients reporting mild pain and nausea. LC rates at 1 and 2 years were 83.1% and 70.2%. Previous local therapy (HR 4.97; p = 0.002), oligoprogression (HR 4.07; p = 0.031) and untreated metastases (HR 4.19; p = 0.027) were associated with worse LC. PFS at 1 and 2 years were 42.2% and 20.0%. Increasing age (HR 1.03; p = 0.010), non-adenoid cystic carcinoma (HR 2.57; p = 0.034) and non-lung metastases (HR 2.20; p = 0.025) were associated with worse PFS. One- and 2-years OS were 81.0% and 67.1%. Worse performance status (HR 2.91; p = 0.049), non-salivary primary (HR 19.9; p = 0.005), non-lung metastases (HR 2.96; p = 0.040) were correlated with inferior OS.</p> <p><strong>Conclusions: </strong>SBRT can be considered a safe metastasis-directed therapy in oligometastatic HNC. Efficacy of the treatment seems to be higher when administered upfront in the management of metastatic disease; however, selection of patients need to be improved due to the relevant risk of appearance of new metastatic site after SBRT.</p>
Can Epidermal Growth Factor Receptor Improve the Postoperative Survivorship for Inoperable Non-small Cell Lung Cancer With Spinal Metastasis ?
ClinicalTrials.gov study NCT02740894. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Hypoxic stabilization of RIPOR3 mRNA via METTL3-mediated m6A RNA methylation drives breast tumor growth and metastasis [m6A-seq-T47D]
GEO Series GSE264245. Homo sapiens. 12 samples. Type: Methylation profiling by high throughput sequencing.
In vivo selection reveals long non-coding RNAs implicated in colon to liver metastasis
GEO Series GSE145749. Homo sapiens. 6 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Hypoxic stabilization of RIPOR3 mRNA via METTL3-mediated m6A RNA methylation drives breast tumor growth and metastasis [m6A-seq-sgControl and sgMETTL3]
GEO Series GSE264247. Homo sapiens. 16 samples. Type: Methylation profiling by high throughput sequencing.
Glucocorticoid promotes metastasis of colorectal cancer via co-regulation of glucocorticoid receptor and TET2 (RNA-Seq)
GEO Series GSE256159. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.
Viral-directed augmentation of Kupffer cell cross-presentation provokes anti-tumor immunity against liver metastasis
GEO Series GSE284315. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
LIN28B alters ribosomal dynamics to promote metastasis in MYCN-driven malignancy (RIP-Seq)
GEO Series GSE183336. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
The regulators of peroxisomal acyl-carnitine shuttle CROT and CRAT promote metastasis in melanoma
GEO Series GSE208547. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Ceramides drive colorectal cancer metastasis through a revival stemness program [BulkRNAseq_HFD]
GEO Series GSE286167. Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.