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4,107 results for “pointing”
Weyl points in the multi-terminal Hybrid Superconductor-Semiconductor Nanowire devices
<p>Code and data points to obtain Figures in the manuscript</p>
Data from: Temperature drives epidemics in a zooplankton-fungus disease system: a trait-driven approach points to transmission via host foraging
Climatic warming will likely have idiosyncratic impacts on infectious diseases, causing some to increase while others decrease or shift geographically. A mechanistic framework could better predict these different temperature-disease outcomes. However, such a framework remains challenging to develop, due to the non-linear and (sometimes) opposing thermal responses of different host and parasite traits, and due to the difficulty of validating model predictions with observations and experiments. We address these challenges in a zooplankton-fungus (Daphnia dentifera-Metschnikowia bicuspidata) system. We test the hypothesis that warmer temperatures promote disease spread and produce larger epidemics. In lakes, epidemics that start earlier and warmer in autumn grow much larger. In a mesocosm experiment, warmer temperatures produced larger epidemics. A mechanistic model parameterized with trait assays revealed that this pattern arose primarily from the temperature-dependence of transmission rate (β), governed by the increasing foraging (and hence parasite exposure) rate of hosts (f). In the trait assays, parasite production seemed sufficiently responsive to shape epidemics as well; however, this trait proved too thermally insensitive in the mesocosm experiment and lake survey to matter much. Thus, in warmer environments, increased foraging of hosts raised transmission rate, yielding bigger epidemics through a potentially general, exposure-based mechanism for ectotherms. This mechanistic approach highlights how a trait-based framework will enhance predictive insight into responses of infectious disease to a warmer world.
Data from: Genome-wide association study in Arabidopsis thaliana of natural variation in seed oil melting point, a widespread adaptive trait in plants
Seed oil melting point is an adaptive, quantitative trait determined by the relative proportions of the fatty acids that compose the oil. Micro- and macro-evolutionary evidence suggests selection has changed the melting point of seed oils to covary with germination temperatures because of a trade-off between total energy stores and the rate of energy acquisition during germination under competition. The seed oil compositions of 391 natural accessions of Arabidopsis thaliana, grown under common-garden conditions, were used to assess whether seed oil melting point within a species varied with germination temperature. In support of the adaptive explanation, long-term monthly spring and fall field temperatures of the accession collection sites significantly predicted their seed oil melting points. In addition, a genome-wide association study (GWAS) was performed to determine which genes were most likely responsible for the natural variation in seed oil melting point. The GWAS found a single highly significant association within the coding region of FAD2, which encodes a fatty acid desaturase central to the oil biosynthesis pathway. In a separate analysis of fifteen a priori oil synthesis candidate genes, two (FAD2 and FATB) were located near significant SNPs associated with seed oil melting point. These results comport with others' molecular work showing that lines with alterations in these genes affect seed oil melting point as expected. Our results suggest natural selection has acted on a small number of loci to alter a quantitative trait in response to local environmental conditions.
Data from: Human behaviours associated with dominance in elite bouts: a comparison of amateur boxing winners and losers under the Ten Point Must System
Humans commonly ascertain physical dominance through non-lethal fighting by participating in combat sports. However, the behaviours that achieve fight dominance are not fully understood. Amateur boxing competition, which is judged using the subjective "Ten Point Must-System", provides insight into fight dominance behaviours. Notational analysis was performed on 26 elite male competitors in a national boxing championship. Behavioural (guard-drop time; movement style [stepping/bouncing time]; clinch-time; interaction-time) and technical (total punches; punches landed [Hit]; air punches [%Air]; defence) measures were recorded. Participants reported effort required (0-100%) and perceived effect of fatigue on their own performance (5-point Likert scale) following bouts. Differences between winners and losers, and changes across the duration of the bout were examined. Winners punched more accurately than losers (greater %Hit [33% vs. 23%] and lower %Air [17% vs. 27%]) but total punches, defence and interaction-time were similar. From rounds 1-2, clinch-time and guard drops increased whilst bouncing decreased. Perceived effect of fatigue increased throughout the bout while perceived effort increased only from rounds 2-3. %Hit and movement index together in regression analysis correctly classified 85% of bout outcomes, indicating that judges (subjectively) chose winning (dominant) boxers according to punch accuracy and style, rather than assertiveness (more punches thrown). Boxers appear to use tactical strategies throughout the bout to pace their effort and minimise fatigue (increased guard drops, reduced bouncing), but these did not influence perceived dominance or bout outcome. These results show that judges use several performance indicators not including the total number of successful punches thrown to assess fight dominance and superiority between fighters. These results provide valuable information as to how experienced fight observers subjectively rate superiority and dominance during one-on-one human fighting.
Data from: Prospective, observational study comparing automated and visual point-of-care urinalysis in general practice
Objective Point-of-care testing (POCT) urinalysis might reduce errors in (subjective) reading, registration and communication of test results, and might also improve diagnostic outcome and optimise patient management. Evidence is lacking. In the present study, we have studied the analytical performance of automated urinalysis and visual urinalysis compared with a reference standard in routine general practice. Setting The study was performed in six general practitioner (GP) group practices in the Netherlands. Automated urinalysis was compared with visual urinalysis in these practices. Reference testing was performed in a primary care laboratory (Saltro, Utrecht, The Netherlands). Primary and secondary outcome measures Analytical performance of automated and visual urinalysis compared with the reference laboratory method was the primary outcome measure, analysed by calculating sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) and Cohen's κ coefficient for agreement. Secondary outcome measure was the user-friendliness of the POCT analyser. Results Automated urinalysis by experienced and routinely trained practice assistants in general practice performs as good as visual urinalysis for nitrite, leucocytes and erythrocytes. Agreement for nitrite is high for automated and visual urinalysis. κ's are 0.824 and 0.803 (ranked as very good and good, respectively). Agreement with the central laboratory reference standard for automated and visual urinalysis for leucocytes is rather poor (0.256 for POCT and 0.197 for visual, respectively, ranked as fair and poor). κ's for erythrocytes are higher: 0.517 (automated) and 0.416 (visual), both ranked as moderate. The Urisys 1100 analyser was easy to use and considered to be not prone to flaws. Conclusions Automated urinalysis performed as good as traditional visual urinalysis on reading of nitrite, leucocytes and erythrocytes in routine general practice. Implementation of automated urinalysis in general practice is justified as automation is expected to reduce human errors in patient identification and transcribing of results.
Data from: Retrospective study using magnetic resonance imaging (MRI) to measure depths of acupuncture points in neck and shoulder region
Objectives: There are safety issues associated with acupuncture treatment. Previous studies regarding needling depth of acupuncture points revealed inconsistent results due to vague depth definition, acupuncture point localisation and measuring tools. The objective of this study is to find and compare the differences of the mean depths of 11 acupuncture points in the neck and shoulder region between subjects, with variables including gender and body mass index (BMI). Setting: This study was conducted at a single medical center in Taiwan. Participants: Three hundred and ninety-four participants were included in this study. Participants were grouped according to gender and BMI. Acupuncture points were localised by WHO standard and measured by MRI. Outcome measures: The distance from the needle insertion point (surface of the skin) to any tissues that would cause possible/severe complications. Results: Mean depths of 11 points were obtained in groups of different BMI and gender. Mean depths of all participants regardless of BMI and gender are as follows, in centimetres: GB21=5.6, SI14=5.2, SI15=8.8, GV15=4.9, GV16=4.6, GB20=5.0, ST9=1.6, SI16=1.8, SI17=2.4, TE16=3.1, LI18=1.3. Participants with higher BMI had greater measured depths in both gender groups. Male participants had larger mean depths than female participants regardless of BMI except in SI17 and LI18. When taking BMI into consideration, depths in male participants are greater than in female participants in most of the points except the following: GB21, TE16 in obesity group; ST9 in underweight and obesity group; SI16 in ideal body weight, overweight and obesity group; SI17, LI18 in each group. Conclusions: Participants with higher BMI had greater measured depths and males tended to have greater depths in most of the points. Clinical practitioners are recommended to consider this information to prevent complications when applying acupuncture treatment to their patients.
Data from: Analytical performance, agreement and user-friendliness of six point of care testing urine analysers for urinary tract infection in general practice.
Objective: Various point-of-care testing (POCT) urine analysers are commercially available for routine urine analysis in general practice. The present study compares analytical performance, agreement and user-friendliness of six different POCT urine analysers for diagnosing urinary tract infection in general practice. Setting: All testing procedures were performed at a diagnostic centre for primary care in the Netherlands. Urine samples were collected at four general practices. Primary and secondary outcome measures: Analytical performance and agreement of the POCT analysers regarding nitrite, leucocytes and erythrocytes, with the laboratory reference standard, was the primary outcome measure, and analysed by calculating sensitivity, specificity, positive and negative predictive value, and Cohen's κ coefficient for agreement. Secondary outcome measures were the user-friendliness of the POCT analysers, in addition to other characteristics of the analysers. Results: The following six POCT analysers were evaluated: Uryxxon Relax (Macherey Nagel), Urisys 1100 (Roche), Clinitek Status (Siemens), Aution 11 (Menarini), Aution Micro (Menarini) and Urilyzer (Analyticon). Analytical performance was good for all analysers. Compared with laboratory reference standards, overall agreement was good, but differed per parameter and per analyser. Concerning the nitrite test, the most important test for clinical practice, all but one showed perfect agreement with the laboratory standard. For leucocytes and erythrocytes specificity was high, but sensitivity was considerably lower. Agreement for leucocytes varied between good to very good, and for the erythrocyte test between fair and good. First-time users indicated that the analysers were easy to use. They expected higher productivity and accuracy when using these analysers in daily practice. Conclusions: The overall performance and user-friendliness of all six commercially available POCT urine analysers was sufficient to justify routine use in suspected urinary tract infections in general practice.
Data from: Point-Combination Transect (PCT): incorporation of small underwater cameras to study fish communities
1. Available underwater visual census methods such as line transects or point count observations are widely used to obtain community data of underwater species assemblages, despite their known pit-falls. As interest in the community structure of aquatic life is growing, there is need for more standardized and replicable methods for acquiring underwater census data. 2. Here, we propose a novel approach, Point-Combination Transect (PCT), which makes use of automated image recording by small digital cameras to eliminate observer and identification biases associated with available underwater visual census methods. We conducted a pilot study at Lake Tanganyika, demonstrating the applicability of PCT on a taxonomically and phenotypically highly diverse assemblage of fishes, the Tanganyikan cichlid species-flock. 3. We conducted 17 PCTs consisting of five GoPro cameras each and identified 22'867 individual cichlids belonging to 61 species on the recorded images. This data was then used to evaluate our method and to compare it to traditional line transect studies conducted in close proximity to our study site at Lake Tanganyika. 4. We show that the analysis of the second hour of PCT image recordings (equivalent to 360 images per camera) leads to reliable estimates of the benthic cichlid community composition in Lake Tanganyika according to species accumulation curves, while minimizing the effect of disturbance of the fish through SCUBA divers. We further show that PCT is robust against observer biases and outperforms traditional line transect methods.
Data from: PCNT point mutations and familial intracranial aneurysms
Objective: To identify novel genes involved in the etiology of intracranial aneurysms (IA) and / or subarachnoid hemorrhages (SAH) using whole exome sequencing. Methods. In the present study we performed whole exome sequencing in thirteen individuals from three families with an autosomal dominant IA/SAH inheritance pattern to look for candidate genes for disease. Additionally, we sequenced PCNT exon 38 in 161 sporadic IA/SAH patients in order to find additional carriers of potential pathogenic variants. Results. We identified two different variants in exon 38 from the PCNT gene shared between affected members from two different families with either IA or SAH (p.V2811L and p.R2728C). One hundred and sixty four samples with either SAH or IA were Sanger sequenced for the PCNT exon 38. Seven missense mutations were identified. We also found a second p.V2811L carrier in a family with a history of neurovascular diseases. Conclusions. The PCNT gene encodes a protein that is involved in the process of microtubule nucleation and organization in interphase and mitosis. Biallelic loss-of-function mutations in PCNT cause a form of primordial dwarfism (MOPD-II) and ~50% of these patients will develop neurovascular abnormalities, including IAs and SAH. Additionally, a complete Pcnt knock-out mouse model (PcntM-/-) published previously showed general vascular abnormalities, including intracranial hemorrhage. The variants in our families lie in the highly conserved PCNT protein-protein interaction domain, making PCNT a highly plausible candidate gene in cerebrovascular disease.
Schooner 02: 25mm Point Cloud
Here's another test - the point cloud filtered to 25mm spacing Source: Objaverse 1.0 / Sketchfab
Pointe de la Parata, Corsica
494 photos from Ph3pro Processed via Dronedeploy Shooting at 9am Source: Objaverse 1.0 / Sketchfab
FIGURE 1 in Cetopirus complanatus (Cirripedia: Coronulidae) from the late Middle Pleistocene human settlement of Pinnacle Point 13 B (Mossel Bay, South Africa)
FIGURE 1. Location and landscape of the study area.
FIGURES 19–21 in Fossil butterflies, calibration points and the molecular clock (Lepidoptera: Papilionoidea)
FIGURES 19–21. Three phylogenetic trees for Nymphalidae: Satyrinae. See text for explanation.
Relocating the Full-Ocean-Depth Multifunctional Landers Seafloor Landing Point in the Challenger Deep Based On A Seismological Approach: A Precise Noninversive US-DTM Method Challenges the Traditional Inversive MC Method
<p>The SEGY format raw OBS-Lander data</p>
Data underpinning "Quantum Effects on Unconventional Pinch Point Singularities"
<p>Raw data set and evaluation scripts used for publication.</p><p>To reproduce the plots, it is recommended to execute individual code cells in the .jl files in a notebook workflow.</p>
Data supplement for paper on Gnuastro's zero point measurement script
<p>Data supplements to the paper titled "<em>Gnuastro: Estimating the Zero Point Magnitude in Astronomical Imaging"</em>, published in Research Notes of the American Astronomical Society (RNAAS) journal (<a href="https://arxiv.org/abs/2312.04263">arXiv:2312.04263</a>). This paper introduces a recently added program to GNU Astronomy Utilities (<a href="https://gnu.org/s/gnuastro">Gnuastro</a>). This repository contains all the necessary inputs and output data (listed below). This paper is written in <a href="https://maneage.org">Maneage</a> and its source is available in <a href="https://codeberg.org/gnuastro/papers/src/branch/zeropoint">Codeberg</a>. For more information on how to reproduce this paper, see the <a href="https://codeberg.org/gnuastro/papers/src/branch/zeropoint/README.md">README.md</a> and <a href="https://codeberg.org/gnuastro/papers/src/branch/zeropoint/README-hacking.md">README-hacking.md</a>. The version string e31dd15 (which is imprinted on some file names and hard-coded in others), represents the Git commit used for this publication. The source of this project is also archived in <a href="https://archive.softwareheritage.org/swh:1:dir:8b2d1f63be96de3de03aa3e2bb68fa7fa52df56f;origin=https://codeberg.org/gnuastro/papers;visit=swh:1:snp:e37e226bab517eef24d854467682b2fcf5d7dc32;anchor=swh:1:rev:ea682783d83707c0e1d114a5de74a100be9f545d">SoftwareHeritage</a>.</p> <p>A brief description of the contents in this repository:</p> <ul> <li><a href="../records/10256845/files/paper-e31dd15.pdf?download=1">paper-e31dd15.pdf</a>: The complete PDF of the paper.</li> <li><a href="../records/10256845/files/sdss-dr12-catalog.fits?download=1">sdss-dr12-catalog.fits:</a> SDSS DR12 catalog which overlaps with input image, to find the zero point magnitude with reference catalog (in this paper SDSS catalog is reference catalog).</li> <li><a href="../records/10256845/files/gaia-dr3-overlap-ra-dec.fits?download=1">gaia-dr3-overlap-ra-dec.fits</a>: Gaia catalog to use for finding stars in images.</li> <li><a href="../records/10256845/files/6-arcsec-zp-with-ref-img.txt?download=1">6-arcsec-zp-with-ref-img.txt</a>: Output data files that are used in the demonstration the pink filled circles in left panel of plot in the paper.</li> <li><a href="../records/10256845/files/2-arcsec-zp-with-ref-img.txt?download=1">2-arcsec-zp-with-ref-img.txt</a>: Output data files that are used in the demonstration the blue filled circles in left panel of plot in the paper.</li> <li><a href="../records/10256845/files/6-arcsec-zp-with-ref-cat.txt?download=1">6-arcsec-zp-with-ref-cat.txt</a>: Output data files that are used in the demonstration the purple filled circles in right panel of plot in the paper.</li> <li><a href="../records/10256845/files/2-arcsec-zp-with-ref-cat.txt?download=1">2-arcsec-zp-with-ref-cat.txt</a>: Output data files that are used in the demonstration the yellow filled circles in right panel of plot in the paper. </li> </ul> <p>For any issues or questions on this project, please contact Sepideh Eskandarlou (corresponding author in PDF).</p>
GT Points
<p>Ground Truth(GT) points collected during 12th August 2019, campaign is provided in .xlsx format</p>
Supplementary material 1 from: Magesh S, Jonsson V, Bengtsson-Palme J (2019) Mumame: a software tool for quantifying gene-specific point-mutations in shotgun metagenomic data. Metabarcoding and Metagenomics 3: e36236. https://doi.org/10.3897/mbmg.3.36236
Table S1
Supplementary material 2 from: Magesh S, Jonsson V, Bengtsson-Palme J (2019) Mumame: a software tool for quantifying gene-specific point-mutations in shotgun metagenomic data. Metabarcoding and Metagenomics 3: e36236. https://doi.org/10.3897/mbmg.3.36236
Figure S1
Golden Gate Bridge - Point Cloud Portrait
Point cloud obtained from drone video Source: Objaverse 1.0 / Sketchfab
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.