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239
datasets available to search
ShareScore release 0.9.0
Dataset results
239 results for “β-Cell”
An adult clock component links circadian rhythms to pancreatic β-cell maturation
GEO Series GSE289105. Mus musculus. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Mesenchymal stem cells receive adaptive islet-derived exosomal miR-151 to promote β-cell compensation in obesity
GEO Series GSE307474. Mus musculus. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Pancreatic β-cell specific Ets-1 inhibition treats type 2 diabetes via revitalized insulin production
GEO Series GSE214924. Mus musculus. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Maintenance of β-cell identity through the transcription co-factors TBL1X and TBL1XR1
GEO Series GSE283723. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Nkx6.1 β-cell expansion pathway
GEO Series GSE55079. Rattus norvegicus. 36 samples. Type: Expression profiling by array.
Insulin secretory granules release exosomal miR-503 to promote insulin resistance and β-cell senescence.
GEO Series GSE155798. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
cGAS Suppresses β-cell Proliferation by a STING-independent but CEBPβ-dependent Mechanism
GEO Series GSE264386. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Zinc accumulation-induced integrated stress response triggers β-cell identity loss
GEO Series GSE236316. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Increased β-cell proliferation prior to immune-cell invasion prevents progression of type 1 diabetes
GEO Series GSE128315. Mus musculus. 23 samples. Type: Expression profiling by array.
tRNA-derived fragments regulate the functional maturation of neonatal β-cells [ncRNA-Seq]
GEO Series GSE163582. Rattus norvegicus. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Context-dependent actions of Exendin-4 on β-cell function and dynamic changes in islet gene expression over time in vivo
GEO Series GSE37936. Mus musculus. 60 samples. Type: Expression profiling by array.
Short telomeres compromise β-cell signaling and survival
GEO Series GSE25040. Mus musculus. 6 samples. Type: Expression profiling by array.
Propargite, an environmental chemical, interacts with GWAS identified diabetes genes to impact human pancreatic β-cell death
GEO Series GSE83782. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Adipocyte-derived extracellular vesicles regulate survival and function of pancreatic β-cells
GEO Series GSE158654. Homo sapiens; Mus musculus. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing.
tRNA-derived fragments regulate the functional maturation of neonatal β-cells [RNA-Seq]
GEO Series GSE163584. Rattus norvegicus. 8 samples. Type: Expression profiling by high throughput sequencing.
Propargite, an environmental chemical, interacts with GWAS identified diabetes genes to impact human pancreatic β-cell death [PTPN2 knockout]
GEO Series GSE83781. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Bromodomain protein inhibition protects β-cells from cytokine-induced death and dysfunction via antogonism of NF-κB pathway
GEO Series GSE160573. Rattus norvegicus. 12 samples. Type: Expression profiling by high throughput sequencing.
The mitochondrial enzyme pyruvate carboxylase restricts pancreatic β-cell senescence by blocking p53 activation
GEO Series GSE278865. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Association of serum lipids with β-cell function in obese children and adolescents
<p>Few data are available on the association between serum lipids and insulin secretion (ISEC) in children. We evaluated the association of triglycerides (TG), HDL cholesterol (HDL-C) and LDL cholesterol (LDL-C) with ISEC in 1150 non-diabetic obese children and adolescents using multivariable robust median regression. The following models were employed: (1) IGI or incAUCR as the ISEC response variable; (2) QUICKI, OGIS, the Stumvoll index or the Matsuda insulin sensitivity index as the insulin sensitivity (ISEN) predictor; (3) TG, HDL-C and LDL-C as the predictors of interest; (4) 120-min glucose, age, sex and body mass index as confounders. LDL-C and TG were not associated with ISEC in any model. In three out of four IGI models, an increase of 1 interquartile range (IQR) of HDL-C was associated with a decrease of median incAUCR ranging from −9 (robust 95% CI −17 to −2) to −8 (−14 to −1) pmol/mmol. In two out of four incAUCR models, an increase of 1 IQR of HDL-C was associated with a decrease of median IGI ranging from −8 (−15 to −1) to −7 (−11 to −2) pmol/mmol. TG and LDL-C are not associated and HDL-C is inversely associated with ISEC in obese children and adolescents.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.