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3,537 results for “Chronic Pain”
Managing Pain and Cognitions in Older Adults With Mild Cognitive Impairment or Memory Related Problems and Chronic Pain
ClinicalTrials.gov study NCT04044183. IPD Sharing: NO. Countries: 1. Publications: 2.
A Safety and Effectiveness Study of Intraspinal Gabapentin (MDT2004) for the Treatment of Chronic Pain
ClinicalTrials.gov study NCT00414466. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Positive Affect as a Source of Resilience for Adults in Chronic Pain
ClinicalTrials.gov study NCT04869345. IPD Sharing: YES. Countries: 1. Publications: 3.
A Study of Duloxetine (LY248686) in Participants With Chronic Osteoarthritis and Knee Pain in Japan
ClinicalTrials.gov study NCT02248480. IPD Sharing: YES. Countries: 1. Publications: 7.
Fentanyl Buccal Tablets Versus Immediate Release Oxycodone for Breakthrough Pain in Patients With Chronic Pain
ClinicalTrials.gov study NCT00813488. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Optimizing Psychotherapy for Older Veterans With Chronic Pain
ClinicalTrials.gov study NCT03918642. IPD Sharing: NO. Countries: 1. Publications: 1.
Exercise Into Pain in Chronic Rotator Cuff Related Shoulder Pain: a Prospective Single-Group Feasibility Study
ClinicalTrials.gov study NCT04154345. IPD Sharing: NO. Countries: 1. Publications: 1.
Exercise as Medicine for Pediatric Chronic Pain
ClinicalTrials.gov study NCT07182006. IPD Sharing: UNDECIDED. Countries: 1. Publications: 6.
A network pharmacology approach to predict potential targets and mechanisms of Gui Zhi-Shao Yao herb pair in treating chronic pain with comorbid anxiety and depression
Open the record for dataset details and reuse information.
Data computational model parameters of nociceptive medullary dorsal horn projection neuron from: Opposite regulation of medullary pain-related projection neuron excitability in acute and chronic pain
Open the record for dataset details and reuse information.
Data from: Randomized study of the impact of a therapeutic education program on patients suffering from chronic low-back pain who are treated with transcutaneous electrical nerve stimulation
Background: Transcutaneous electrical nerve stimulation (TENS) is often used for the treatment of low-back pain (LBP). However, its effectiveness is controversial. Objective: To determine the efficacy of TENS in the treatment LBP when associated to a therapeutic education program (TEP). Design: Open randomized monocentric study. Setting: University hospital between 2010 and 2014. Patients: A total of 97 patients suffering from LBP. Interventions: Routine care (TENS group) or routine care plus a therapeutic education program (TENS-TEP group) based on consultation support by a pain resource nurse Main outcome measures: EIFEL and Dallas Pain Questionnaire scores. Results: Twenty-two patients (44%) were still assessable at the end-of-study visit, whereas 33 (70%) were assessable at the same time point in the TENS-TEP group (P = 0.013). The EIFEL score and the Dallas score had a similar evolution over time between groups (p = 0.18 and p = 0.50 respectively). Similarly, there were no significant differences between the groups with respect to resting pain scores (p = 0.94 for back pain and p = 0.16 for leg pain) and movement pain scores (p = 0.52 for back pain and p = 0.56 for leg pain). At Month 6, there was no significant difference between the groups (p = 0.85) with regard to analgesics and social impact. Two patients presented a serious adverse event during the study (one in each group) but non-attributable to the treatment studied. Conclusion: This study does not support the use of TENS in the treatment of patients with chronic LBP even though patients benefited from a therapeutic education program by a pain resource nurse. However, the higher number of premature withdrawals in the TENS group may be due to early withdrawal of patients who did not experience improvement of their symptoms.
Dataset for Effects Effects of Soft Tissue Mobilization with TECAR Therapy Using Bracelet Electrodes in Women with Chronic Non-specific Neck Pain
<p>This dataset contains anonymized data from a randomized controlled trial (RCT) evaluating the effectiveness of combining Soft Tissue Mobilization Techniques (STMT) with Capacitive and Resistive Electric Transfer Therapy (TECAR) in women with Chronic Non-Specific Neck Pain (CNSNP). Data include assessments at baseline, the 5th week, and the 6th-month follow-up for variables related to pain intensity, disability, and range of motion (ROM).</p>
Bracing adults with chronic low back pain secondary to severe scoliosis: six months results of a prospective pilot study.
<p>Dataset from the paper: Bracing adults with chronic low back pain secondary to severe scoliosis: six months results of a prospective pilot study. Eur Spine J. 2021 Oct;30(10):2962-2966. doi: 10.1007/s00586-021-06808-1. Epub 2021 Mar 17. PMID: 33733328.</p> <p>Abstract</p> <p><strong>Purpose: </strong>Adult scoliosis is sometimes associated with back pain and severe curves can progress over time. Despite scoliosis has been estimated to affect up to 68% of the population over 60, there is scant literature about conservative treatment for adult scoliosis. Recently, we tested a new brace designed to alleviate pain for adult patients with chronic pain secondary to scoliosis. The study aims to test the efficacy of a prefabricated brace in reducing pain in adult scoliosis patients.</p> <p><strong>Methods: </strong>Twenty adults (age 67.8 ± 10.5, curve 61.9 ± 12.6° Cobb) with chronic low back pain (cLBP) secondary to Idiopathic Scoliosis (IS) were included. Patients were evaluated at baseline immediately before starting with the brace and after 6 months. Outcome measures were GRS, Oswestry Disability Index (ODI), Roland Morris Questionnaire (RM), COMI. The paired t test, ANOVA and Wilcoxon tests were used for statistical analysis RESULTS: At six months, worst pain, leg pain and back pain were significantly improved: from 7.15 to 5.60, from 5.65 to 4.35 and from 6.55 to 5.25 (p < 0.05). Sixty-five percent of patients achieved the minimal clinically important difference of 2 points for worst pain and leg pain, 55% for back pain. RM and COMI improved (p < 0.05), no differences for ODI.</p> <p><strong>Conclusion: </strong>The prefabricated brace showed a significant improvement at 6 months of worst, leg and back pain in most patients in a group of adult women with IS and cLBP. The quality of life didn't change in a clinically significant way even if the patients reported satisfaction with the treatment. Trial registration number and date of registration: ClinicalTrials.gov Identifier: <a href="http://clinicaltrials.gov/show/NCT02643290">NCT02643290</a>, December 31, 2015.</p>
Development of chronic pain after posterolateral and axillary approaches for thoracic surgery: A prospective monocentric observational study
<p class="MDPI17abstract"><span>Mini-invasive thoracotomies may reduce chronic</span><span> pain and pain-related functional impairment. The aims of part 2 of the study were to assess their incidence after posterolateral and axillary thoracotomies and to identify potential factors of chronic pain. Patients undergoing a posterolateral (79 patients) or axillary (79 patients) thoracotomy between July 2014 and November 2015 were analyzed in this prospective monocentric cohort study. At the 4-month assessment, more patients had chronic pain in the posterolateral group (60.8% vs 40.5%; p=0.017). There was a significant difference between groups favoring the axillary group: less level of catastrophism (p=0.021) and less impact of pain on daily activities (globally, p=0.009; routine activities subscore, p=0.010, chosen activity subscore, p=0.030). According to a multinomial logistic model multivariable, three factors are associated with the presence of chronic pain: the presence of pain before surgery (OR=2.36, CI 95% [1.03-5.39]), a large posterolateral incision (OR=4.14 [1.25-13.72]) and the intensity of pain during mobilization of the ipsilateral shoulder at postoperative day 6 (OR=1.37 [1.10-1.70]). In conclusion, chronic pain is less frequent after an axillary approach than after a posterolateral one. Identified risk factors for chronic pain should lead to more aggressive management of preoperative and early postoperative pain and favor the mini-invasive approach.</span></p>
Predictors of depression, anxiety and stress indicators in a cohort of women with chronic pelvic pain data set
<p>Data set for submission of paper 'Predictors of depression, anxiety and stress indicators in a cohort of women with chronic pelvic pain'</p>
Predictors of depression, anxiety and stress indicators in a cohort of women with chronic pelvic pain - data set 2
<p>Data set for PPSA study - 2. A second data set was created for the PPSA study publication to isolate variables of interest to make the statistics manageable, due to the sheer number of variables in the initial data set </p>
Virtual Reality Intervention in Chronic Musculoskeletal Pain Syndromes and Fibromyalgia
<p>XLSX file dataset for "Effectiveness and User Experience of a <span>Virtual</span> <span>Reality</span> Intervention in Chronic Musculoskeletal Pain Syndromes and Fibromyalgia". PLOS Digital Health.</p>
Volitional Action Control and Depression in Chronic Pain: Does Action versus State Orientation Moderate the Relations of Pain-Related Cognitions to Depression?
<p>The rationale of this study was to better understand the interplay between content- and function-focused variables that are assumed to contribute to depression due to motivational and volitional deficits. Therefore, we stepwise examined the conditional indirect and direct relations of pain-related cognitions to depression. Subjective helplessness was included as presumably mediating the relations of catastrophizing and thought suppression to depression due to motivational deficits. In addition, moderating effects of dispositional action versus state orientation were analyzed, whereby state orientation indicates volitional deficits in coping with distress<strong>. </strong></p> <p>The data acquisition for this project was funded by the German Pension Insurance (Deutsche Rentenversicherung Bund) and the Federal Ministry of Education and Research (BMBF) within the research priority “Chronic diseases and patient orientation” - Grant number: 0421-FSCP-0529.</p>
The predictive role of executive functions and psychological factors on chronic pain after orthopaedic surgery A longitudinal cohort study
<p>This is a dataset from a longitudinal cohort study. Patients listed for orthopaedic surgery were enrolled. Variables measured<br> before surgery were pain intensity, the sensory, affective, cognitive and mixed components of pain, state and trait variables associated with the psychological status of the patient, fear of movement, pain catastrophizing, visual attention and cognitive flexibility. Pain intensity and the components<br> of pain were re-evaluated after surgery and after three months. 167 patients were enrolled.</p>
Assessment of spinal cord stimulation and radiofrequency Chronic pain and psychological impact
<p>Pain has a major impact on anxiety and depression levels. The aim of this study is to demonstrate how these symptoms (depression and anxiety) could positively influence the perception of pain after neurostimulation system implantation.We enrolled 100 patients and divided in 2 different groups, by using tests screening such as Beck Depression Inventory (BDI), Hamilton Anxiety Rating Scale (HAM-A), Nursing Rating Scale (NRS): the group with spinal cord stimulation (SCS) and the group with pulsed spinal cord radiofrequency (RFP).We highlighted a significant decrease of scores (BDI, HAM-A, NRS) in each group between T0 (baseline) and T1. Moreover, the intra-group analysis showed a positive significant correlation between NRS and depressive and anxiety symptoms.We assert that the use of alternative methods (SCS and RFP) to the traditional pharmaceutical-surgical treatments, provide the reduction of the algic and anxiety-depressant symptoms, restoring also the perception of psychological well-being.</p>
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Allen Brain Atlas
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.