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ShareScore release 0.9.0
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232 results for “Healthcare Workers”
Prevalence of Tattoos and Piercings in Healthcare Using the Example of Obstetrics Workers
ClinicalTrials.gov study NCT05782530. IPD Sharing: Not stated. Countries: 0. Publications: 0.
The Effect of Automatic Massage Applied to Healthcare Workers on Pain, Fatigue and Psychological Well-being
ClinicalTrials.gov study NCT06504797. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Humanistic Care in Healthcare Workers in Coronavirus Disease 2019
ClinicalTrials.gov study NCT04283838. IPD Sharing: NO. Countries: 0. Publications: 0.
Use of Dynavax Heplisav B in Healthcare Workers Previously Vaccinated With 3-dose Vaccine Who Failed to Demonstrate Seroprotection
ClinicalTrials.gov study NCT04385524. IPD Sharing: NO. Countries: 0. Publications: 0.
Post Exposure Prophylaxis in Healthcare Workers Exposed to COVID-19 Patients
ClinicalTrials.gov study NCT04437693. IPD Sharing: YES. Countries: 0. Publications: 0.
A Cross-sectional Study on the Impact of Shift Work on Diastolic Dysfunction in Healthcare Workers
ClinicalTrials.gov study NCT07331233. IPD Sharing: YES. Countries: 0. Publications: 0.
Hydroxychloroquine Chemoprophylaxis for COVID-19 Infection in High-risk Healthcare Workers.
ClinicalTrials.gov study NCT04370015. IPD Sharing: NO. Countries: 0. Publications: 0.
Changing in adaptive cellular repertoire after different SARS-CoV-2 VOCs infection in a cohort of vaccinated Healthcare workers
<p>Despite currently approved vaccines are highly effective in protecting against hospitalization and severe Covid-19 infections, however, their effectiveness in counteracting symptoms presentation and breakthrough infections appears to decrease over time. How pre-existing immunity responds to new variants with mutated antigens is a crucial information to elucidate the functional interplay between antibodies, B and T cell responses during infection with new SARS-CoV-2 variants. In this study, we monitored the dynamics and persistence of the immune response versus different SARS-CoV-2 variants of concern emerged during the pandemic period (2021-2022), in a cohort of vaccinated health care workers, who experienced breakthrough infection in the Pre-Delta, Delta and Omicron waves. Our results suggest a direct dependence between VOCs and different humoral and B and T cells balance in the post-infection period, despite the administration of a different number of vaccine doses and the elapsed time since the last vaccination.</p>
Burnout syndrome and its determinants among healthcare workers during the first wave of the Covid-19 outbreak in Italy: a cross-sectional study to identify sex-related differences.
<p>Brera AS, Arrigoni C, Dellafiore F, Odone A, Magon A, Nania T, Pittella F, Palamenghi L, Barello S, Caruso R. Burnout syndrome and its determinants among healthcare workers during the first wave of the Covid-19 outbreak in Italy: a cross-sectional study to identify sex-related differences. Med Lav. 2021 Aug 26;112(4):306-319. doi: 10.23749/mdl.v112i4.11316. PMID: 34446687; PMCID: PMC8436819.</p> <p><strong>Introduction: </strong>Several studies described burnout levels of healthcare workers (HCWs) during the COVID-19 pandemic; however, sex-related differences remain poorly investigated.</p> <p><strong>Objective: </strong>To describe sex-related differences in burnout and its determinants among HCWs during the first pandemic wave of the COVID-19 in Italy.</p> <p><strong>Methods: </strong>A cross-sectional study was performed between April and May 2020. The framework given by the Job Demands Resources (JD-R) model was used to assess burnout determinants (risk and protective factors).</p> <p><strong>Results: </strong>Male HCWs (n=133) had higher levels of depersonalization than female HCWs (P=0,017) and female HCWs (n=399) reported greater emotional exhaustion rates (P=0,005). Female nurses were the most exposed to burnout (OR=2,47; 95%CI=1,33-4,60; P=0,004), emotional exhaustion (OR=1,89; 95% CI=1,03-3,48; P=0,041), and depersonalization (OR=1,91; 95% CI=1,03-3,53; P=0,039). Determinants of burnout differed between sexes, and some paradoxical associations were detected: the score of job demands was a protective factor in females for burnout, emotional exhaustion, and depersonalization, resilience was a risk factor for males.</p> <p><strong>Conclusions: </strong>This study reveals that the stressors in male and female HCWs tended to be associated with burnout differently. Both sexes showed alarming burnout levels, even if the weights of emotional exhaustion and depersonalization acted in different ways between the sexes. The revealed paradoxical effects in this study could reflect the study's cross-sectional nature, highlighting that more resilient and empathic individuals were more consciously overwhelmed by the challenges related to the COVID-19 pandemic, thus reporting higher scores of emotional exhaustion and burnout. Future in-depth and longitudinal analyses are recommended to further explore sex-related differences in burnout among HCWs.</p>
Genomic surveillance of SARS-CoV-2 in healthcare workers: a critical sentinel group for monitoring the SARS-CoV-2 variant shift
<p>Figure S1. Phylogenetic reconstruction of SARS-CoV-2 sequences distinguished between general population and healthcare workers. Samples correspond to the period of November 17th, 2021 and February 21st, 2022. The phylogenetic tree was reconstructed with 1,000 iterations for Ultra-Fast Bootstrap and SH-like approximate likelihood ratio test (SH-aLRT). Reference (SARS-CoV-2 reference genome - NC_045512).</p>
Anti-Phospholipid Antibodies and Coronavirus Disease 2019: Vaccination Does Not Trigger Early Autoantibody Production in Healthcare Workers
<p>A molecular mimicry between severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) and human proteins supports the possibility that autoimmunity takes place during coronavirus disease 2019 (COVID-19) contributing to tissue damage. For example, antiphospholipid antibodies (aPL) have been reported in COVID-19 as a result of such mimicry and thought to contribute to the immunothrombosis characteristic of the disease. Consistently, active immunization with the virus spike protein may elicit the production of cross-reactive autoantibodies, including aPL. We prospectively looked at the aPL production in healthcare workers vaccinated with RNA- (BNT162b2, n. 100) or adenovirus-based vaccines (ChAdOx1, n. 50). Anti-cardiolipin, anti-beta2 glycoprotein I, anti-phosphatidylserine/prothrombin immunoglobulin G (IgG), IgA, and IgM before and<br> after vaccination were investigated. Anti-platelet factor 4 immunoglobulins were also<br> investigated as autoantibodies associated with COVID-19 vaccination. Additional organ<br> (anti-thyroid) and non-organ (anti-nuclear) autoantibodies and IgG against human<br> proteome were tested as further post-vaccination autoimmunity markers. The<br> antibodies were tested one or three months after the first injection of ChAdOx1 and BNT162b2, respectively; a 12-month clinical follow-up was also performed. Vaccination occasionally induced low titers of aPL and other autoantibodies but did not affect the titer<br> of pre-existing autoantibodies. No significant reactivities against a microarray of approximately 20,000 human proteins were found in a subgroup of ChAdOx1-vaccinees. Consistently, we did not record any clinical manifestation theoretically associated with an underlying autoimmune disorder. The data obtained after the vaccination (two doses for the RNA-based and one dose for the adenovirus-based vaccines), and the clinical follow-up are not supporting the occurrence of an early autoimmune response in this cohort of healthcare workers.</p>
Coping and quality of life differences between emergency and rehabilitation healthcare workers.
<p>Dataset</p>
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