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239
datasets available to search
ShareScore release 0.9.0
Dataset results
239 results for “lung fibroblasts”
Effect of MWCNT on Lung Fibroblast gene expression
GEO Series GSE43515. Homo sapiens. 54 samples. Type: Expression profiling by array.
Redundant effects of Pirfenidone against fibroblast activation and severe fibrotic lung disease
GEO Series GSE199034. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome profile of post-mortem ear and lung fibroblasts
GEO Series GSE136708. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide DNA Methylation Analysis in Lung Fibroblasts Co-cultured with Silica-exposed Alveolar Macrophages
GEO Series GSE93116. Rattus norvegicus. 4 samples. Type: Methylation profiling by high throughput sequencing.
A single-cell gene expression analysis in an in vitro co-culture model containing fibroblast cells directly mixed with NMU-manipulated lung adenocarcinoma cells
GEO Series GSE240911. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
Microarray-analysis of primary lung fibroblasts cell lines (established from 3-4weeks old mice)
GEO Series GSE166781. Mus musculus. 4 samples. Type: Expression profiling by array.
Long noncoding RNA FENDRR inhibits lung fibroblast proliferation via a reduction of beta-catenin
GEO Series GSE175496. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Fibroblast growth factor (FGF) 10 is essential for lung morphogenesis
GEO Series GSE230854. Mus musculus. 68 samples. Type: Expression profiling by array.
MacroH2A1 ChIP-seq from H-RasV12 expressing senescent IMR90 human primary lung fibroblasts
GEO Series GSE64601. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Expression data from LAM-associated fibroblasts and normal human lung fibroblasts co-cultured with TSC2-/- 621-101 cells
GEO Series GSE160618. Homo sapiens. 12 samples. Type: Expression profiling by array.
Deficiency of the Collagen Endocytic Receptor MRC2 Accelerates Mouse Lung Fibroblast Proliferation
GEO Series GSE291404. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Endothelin-1 (ET-1) treated lung fibroblasts
GEO Series GSE981. Homo sapiens. 2 samples. Type: Expression profiling by array.
Paradoxical drug sensitization of lung cancer cells by stromal fibroblast-secreted IGF-binding proteins
GEO Series GSE164750. Homo sapiens. 27 samples. Type: Expression profiling by array.
Time course effect of the glucocorticoid mometasone furoate on the proliferation of primary human lung fibroblasts
GEO Series GSE30242. Homo sapiens. 24 samples. Type: Expression profiling by array.
Primary lung fibroblasts treated with hedgehog agonist, purmorphamine
GEO Series GSE61026. Mus musculus. 6 samples. Type: Expression profiling by array.
The effects of chemokines CXCL1/2/8 on mouse lung fibroblasts
GEO Series GSE131306. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Expression data of stimulated murine primary lung fibroblasts
GEO Series GSE156314. Mus musculus. 9 samples. Type: Expression profiling by array.
Spatial Transcriptomics Reveals Spatially Diverse Cancer-Associated Fibroblast in Lung Squamous Cell Carcinoma Linked to Tumor Progression
<p><span><span>While cancer-associated fibroblasts (CAFs) are crucial in influencing tumor growth and immune responses in lung cancer, we still lack a comprehensive understanding of their spatial organization associated with tumor progression and clinical outcomes. This gap highlights the need to elucidate how the intricate spatial arrangement of CAFs affects their interactions within the tumor microenvironment, ultimately shaping cancer progression and patient prognosis. Here, we unveil the spatial diversity of CAFs in lung squamous cell carcinoma (LUSC), a prevalent and aggressive lung cancer type, elucidating their impact on tumor progression and patient outcomes using spatial transcriptomics (ST). Image-based ST data from 33 LUSC patients demonstrated a significant association of spatial interactions of tumor epithelium and CAFs with tumor size and metabolic activity measured by [<sup>18</sup>F]fluorodeoxyglucose PET. Furthermore, the proximity of fibroblasts to tumor epithelial cells was linked to recurrence-free survival in LUSC patients. By characterizing CAFs based on their spatial relationship, we identified distinct molecular signatures related to spatially distinct fibroblast subpopulations. In addition, barcode-based ST data from 8 LUSC patients revealed spatially overlapping fibroblast regions characterized by upregulated glycolysis pathways. </span></span><span><span><span><span>Our study underscores the importance of the complex spatial dynamics of the tumor microenvironment revealed by ST and its implications for patient outcomes in LUSC.</span></span></span></span></p>
Lymphotoxin Beta Receptor Activity in Fibroblasts Regulates Collagen Synthesis and is Crucial for Lung Fibrosis
GEO Series GSE314060. Homo sapiens. 42 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.