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Dataset results
673 results for “morphine”
Quadratus Lumborum Block vs Intrathecal Morphine for Post-Cesarean Analgesia
ClinicalTrials.gov study NCT06612424. IPD Sharing: NO. Countries: 1. Publications: 2.
Switching From Morphine to Oral Methadone Plus Acetaminophen in the Treatment of Cancer Pain
ClinicalTrials.gov study NCT00525967. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Topical Morphine for Analgesia in Patients With Skin Grafts
ClinicalTrials.gov study NCT00362219. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Treatment of Neonatal Abstinence Syndrome With Clonidine Versus Morphine as Primary Therapy
ClinicalTrials.gov study NCT03092011. IPD Sharing: NO. Countries: 1. Publications: 1.
Decreased Neuraxial Morphine After Cesarean Delivery
ClinicalTrials.gov study NCT04279054. IPD Sharing: NO. Countries: 1. Publications: 17.
The Effect of Adding Nalbuphine to Intrathecal Morphine on Analgesic Efficacy and Side Effects After Cesarean Section
ClinicalTrials.gov study NCT02716129. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Morphine Postoperative Analgesia and Pharmacokinetic/Pharmacodynamic Modeling
ClinicalTrials.gov study NCT01564420. IPD Sharing: Not stated. Countries: 1. Publications: 1.
DATASET OF "Intrathecal morphine and sleep apnoea severity in patients undergoing hip arthroplasty: a randomised, controlled, triple- blinded trial"
<p><strong>Background: </strong>Intrathecal morphine prolongs analgesia after surgery, but has been implicated in postoperative respiratory depression or apnoeic episodes. However, this has not been investigated in a prospective trial using respiratory polygraphy. This randomized controlled triple-blinded trial tested the hypothesis that intrathecal morphine increases sleep apnoea severity, measured using respiratory polygraphy.</p> <p><strong>Methods: </strong>Sixty patients undergoing hip arthroplasty under spinal anaesthesia received either 15 mg isobaric bupivacaine 0.5% with 0.5 mL normal saline 0.9% (control group) or 15 mg isobaric bupivacaine 0.5% with 0.5 mL intrathecal morphine 100 µg (intrathecal morphine group). Respiratory polygraphy was performed before surgery and on the first and third postoperative nights. The primary outcome was the apnoea-hypopnoea index in the supine position (supine AHI) on the first postoperative night. Secondary outcomes included supine AHI on the third postoperative night, oxygen desaturation index (ODI) and respiratory rate in the first and third postoperative nights.</p> <p><strong>Results: </strong>On the first postoperative night, mean (95% confidence interval) values for supine AHI were 20.6 (13.9–27.3) and 21.2 (12.4–30.0) events/h in the control and intrathecal morphine groups, respectively (p=0.90). There were no significant between-group differences for any of the secondary outcomes, except for a significantly higher central and mixed apnoea index preoperatively and significantly lower mean SpO<sub>2</sub> on the third postoperative night in the control group.</p> <p><strong>Conclusions: </strong>Intrathecal morphine did not increase sleep apnoea severity, when measured using respiratory polygraphy. Of note, all patients had an increased number of apnoeic episodes on the third postoperative night.</p>
Data from: Calculating maximum morphine equivalent daily dose from prescription directions for use in the electronic health record: a case report
Objective To demonstrate a process of calculating the maximum potential morphine milligram equivalent daily dose (MEDD) based on the prescription Sig for use in quality improvement initiatives. Methods To calculate an opioid prescription's maximum potential Sig-MEDD, we developed SQL code to determine a prescription's maximum units/day using discrete field data and text-parsing in the prescription instructions. We validated the derived units/day calculation using 3,000 Sigs, then compared the Sig-MEDD calculation against the Epic MEDD calculator. Results Of the 101,782 outpatient opioid prescriptions ordered over one year, 80% used discrete-field Sigs, 7% used free-text Sigs, and 3% used both types. We determined units/day and calculated a Sig-MEDD for 98.3% of all prescriptions, 99.99% of discrete-Sig prescriptions, and 81.5% of free-text-Sig prescriptions. Conclusion Analyzing opioid prescription Sigs to determine a maximum potential Sig-MEDD provides greater insight into a patient's risk for opioid exposure.
Supplementary material 1 from: Rahmadi M, Ardianto C, Nurhan AD, Chasanah RA, Krismonika DI, Puspitasari AD, Suprapti B, Segaran S, Phan C-W, Khotib J (2022) Bisacodyl overcomes morphine-induced constipation by decreasing colonic Aquaporin-3 and Aquaporin-4 expression. Research Results in Pharmacology 8(4): 65-75. https://doi.org/10.3897/rrpharmacology.8.82242
The representative photos of feces with high water content and low water content
Postoperative Hemodynamics Comparison After High Spinal Block With or Without Intrathecal Morphine.
ClinicalTrials.gov study NCT02825056. IPD Sharing: YES. Countries: 0. Publications: 1.
Study of Morphine in Postoperative Infants to Allow Normal Ventilation
ClinicalTrials.gov study NCT00004696. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Trial Comparing Intrathecal Morphine With Placebo In Patients Undergoing Robotic Cardiac Surgery
ClinicalTrials.gov study NCT03241485. IPD Sharing: NO. Countries: 1. Publications: 0.
Intrathecal Morphine in Knee Arthroplasty
ClinicalTrials.gov study NCT00695045. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Effect of Combined Morphine and Duloxetine on Chronic Pain
ClinicalTrials.gov study NCT03249558. IPD Sharing: NO. Countries: 1. Publications: 0.
Wound Infusion vs Spinal Morphine for Post-caesarean Analgesia
ClinicalTrials.gov study NCT02264821. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Morphine
ClinicalTrials.gov study NCT04138615. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Comparison of A Single Dose Combination of Methadone and Morphine With Morphine Alone for Treating Post-operative Pain
ClinicalTrials.gov study NCT00142519. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain
ClinicalTrials.gov study NCT04368364. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study to Evaluate the Effectiveness and Safety of CG5503 (Tapentadol) in the Treatment of Chronic Tumor Related Pain Compared With Placebo and Morphine
ClinicalTrials.gov study NCT00505414. IPD Sharing: Not stated. Countries: 6. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
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International Brain Laboratory public data
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OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.