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239
datasets available to search
ShareScore release 0.9.0
Dataset results
239 results for “mycophenolate mofetil”
Imatinib Mesylate and Mycophenolate Mofetil for Steroid-Refractory Sclerotic/Fibrotic cGVHD in Children
ClinicalTrials.gov study NCT01898377. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Mycophenolate Mofetil (MMF): A Long-Term Data Evaluation
ClinicalTrials.gov study NCT00203671. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Pharmacokinetically-driven Dosing of Mycophenolate Mofetil for the Treatment of Pediatric Proliferative Lupus Nephritis
ClinicalTrials.gov study NCT05101447. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
A Study to Investigate the Tolerability and Safety of Converting Stable Renal Transplant Recipients Who Receive Tacrolimus With or Without Corticosteroids From Mycophenolate Mofetil (MMF) to Enteric-c
ClinicalTrials.gov study NCT00238979. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitors
ClinicalTrials.gov study NCT06279494. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis
ClinicalTrials.gov study NCT02949349. IPD Sharing: NO. Countries: 0. Publications: 0.
Clinical Study to Evaluate the Tolerability, Safety and Efficacy of Enteric-coated Mycophenolate Sodium, After Equimolar Conversion From Mycophenolate Mofetil (MMF), in Patients With Stable Renal Tran
ClinicalTrials.gov study NCT00171392. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Efficacy and Safety of FTY720 Versus Mycophenolate Mofetil (MMF, Roche Brand) in de Novo Adult Renal Transplant Recipients
ClinicalTrials.gov study NCT00239863. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Investigation of the Steady State Pharmacokinetics of Tacrolimus, Mycophenolate Mofetil and Fluvastatin After Renal Transplantation
ClinicalTrials.gov study NCT00223015. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Renal Function Optimization With Mycophenolate Mofetil (MMF) Immunosuppressor Regimes (ALHAMBRA)
ClinicalTrials.gov study NCT00290069. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study Comparing Two Sirolimus Regimens vs. Tacrolimus and Mycophenolate Mofetil Regimen in Kidney Transplant Recipients
ClinicalTrials.gov study NCT00266123. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Extension Study to Assess Tolerability and Safety of Enteric-coated Mycophenolate Sodium in Renal Transplant Recipients Who Received Mycophenolate Mofetil
ClinicalTrials.gov study NCT00238966. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Clinical Study to Evaluate the Tolerability, Safety and Efficacy of Enteric-coated Mycophenolate Sodium After Equimolar Conversion From Mycophenolate Mofetil (MMF) in Patients With Renal Transplant
ClinicalTrials.gov study NCT00171379. IPD Sharing: Not stated. Countries: 0. Publications: 0.
De Novo Everolimus Versus Tacrolimus in Combination With Mofetil Mycophenolate and Low Dose Corticosteroids to Reduce Tacrolimus Induced Nephrotoxicity in Liver Transplantation: a Prospective, Multice
ClinicalTrials.gov study NCT02909335. IPD Sharing: NO. Countries: 0. Publications: 0.
Mycophenolate Mofetil in Myasthenia Gravis
ClinicalTrials.gov study NCT00285350. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Dataset related to article "Dose-Dependent Impairment of the Immune Response to the Moderna-1273 mRNA Vaccine by Mycophenolate Mofetil in Patients with Rheumatic and Autoimmune Liver Diseases"
<p>This record contains data related to article "Dose-Dependent Impairment of the Immune Response to the Moderna-1273 mRNA Vaccine by Mycophenolate Mofetil in Patients with Rheumatic and Autoimmune Liver Diseases"</p> <p>The purpose of this study was to evaluate the efficacy and safety of the Moderna-1273 mRNA vaccine for SARS-CoV-2 in patients with immune-mediated diseases under different treatments. Anti-trimeric spike protein antibodies were tested in 287 patients with rheumatic or autoimmune diseases (10% receiving mycophenolate mofetil, 15% low-dose glucocorticoids, 21% methotrexate, and 58% biologic/targeted synthetic drugs) at baseline and in 219 (76%) 4 weeks after the second Moderna-1273 mRNA vaccine dose. Family members or caretakers were enrolled as the controls. The neutralizing serum activity against SARS-CoV-2-G614, alpha, and beta variants in vitro and the cytotoxic T cell response to SARS-CoV-2 peptides were determined in a subgroup of patients and controls. Anti-SARS-CoV-2 antibody development, i.e., seroconversion, was observed in 69% of the mycophenolate-treated patients compared to 100% of both the patients taking other treatments and the controls (p &amp;lt; 0.0001). A dose-dependent impairment of the humoral response was observed in the mycophenolate-treated patients. A daily dose of &amp;gt;1 g at vaccination was a significant risk factor for non-seroconversion (ROC AUC 0.89, 95% CI 0.80-98, p &amp;lt; 0.0001). Moreover, in the seroconverted patients, a daily dose of &amp;gt;1 g of mycophenolate was associated with significantly lower anti-SARS-CoV-2 antibody titers, showing slightly reduced neutralizing serum activity but a comparable cytotoxic response compared to other immunosuppressants. In non-seroconverted patients treated with mycophenolate at a daily dose of &amp;gt;1 g, the cytotoxic activity elicited by viral peptides was also impaired. Mycophenolate treatment affects the Moderna-1273 mRNA vaccine immunogenicity in a dose-dependent manner, independent of rheumatological disease.</p>
Mycophenolate Mofetil and Abacavir Treatment in HIV Patients With Failed Anti-HIV Treatment
ClinicalTrials.gov study NCT00021489. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Mycophenolate Mofetil Maintenance Therapy for Liver Transplantation
ClinicalTrials.gov study NCT00849238. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Systemic sclerosis skin disease trajectory during mycophenolate mofetil treatment
GEO Series GSE76885. Homo sapiens. 194 samples. Type: Expression profiling by array.
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