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4,600 results for “vascular”
Single-cell analysis uncovers inter- and intra-organ fibroblast heterogeneity and provides criteria for fibroblast identification and discrimination from vascular mural cells [bladder]
GEO Series GSE150289. Mus musculus. 1479 samples. Type: Expression profiling by high throughput sequencing.
Programming to S1PR1+ Endothelial Cell Promotes Restoration of Lung Vascular Integrity
GEO Series GSE165000. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profiling of purified endocardial and coronary vascular endothelial cells, isolated from murine embryonic hearts, at two developmental stages
GEO Series GSE147117. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome profiling of vascular tissues in Angiotensin II-dependent hypertension in vivo
GEO Series GSE75815. Mus musculus. 23 samples. Type: Expression profiling by array.
Pericytes contribute to pulmonary vascular remodeling via HIF2α signaling
GEO Series GSE211985. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Heterogeneous Cardiac- and Neural Crest-Derived Aortic Smooth Muscle Cells have Similar Transcriptional Changes after TGFβ Signaling Disruption [scRNA-seq-of-human-aortic-media-vascular-cells]
GEO Series GSE253934. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
microRNA analysis of supernatants from stromal vascular fraction (SVF) cells derived from healthy controls and lipedema patients
GEO Series GSE138579. Homo sapiens. 12 samples. Type: Other.
Rat models for Portosinusoidal Vascular Disease
GEO Series GSE229380. Rattus norvegicus. 23 samples. Type: Expression profiling by high throughput sequencing.
Organ-differential Regulation of Vascular Development by DEAD-box Helicase 24
GEO Series GSE185261. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Figure 1 from: Bay C (2020) Four decades of new vascular plant records for Greenland. PhytoKeys 145: 63-92. https://doi.org/10.3897/phytokeys.145.39704
Figure 1 The floristic provinces of Greenland (Böcher et al. 1978).
Figure 2 from: Kipkoech S, Melly DK, Muema BW, Wei N, Kamau P, Kirika PM, Wang Q, Hu G (2020) An annotated checklist of the vascular plants of Aberdare Ranges Forest, a part of Eastern Afromontane Biodiversity Hotspot. PhytoKeys 149: 1-88. https://doi.org/10.3897/phytokeys.149.48042
Figure 2 The classes of vascular plants taxa in Aberdare Ranges Forest.
Data from: Sleep disordered breathing is associated with brain vascular reactivity in spinal cord injury
Objective: Our goal was to determine the population-level odds of individuals with SCI experiencing fatigue and sleep apnea, to elucidate relationships with level and severity of injury, and to examine associations with abnormal cerebrovascular responsiveness. Methods: We used population-level data, meta-analyses, and primary physiological assessments to provide a large-scale integrated assessment of sleep-related complications after SCI. Population-level and meta-analyses included more than 60,000 able-bodied individuals and more than 1,800 individuals with SCI. Physiological assessments were completed on a homogenous sample of individuals with cervical SCI, and matched controls. We examined the prevalence of 1) self-reported chronic fatigue, 2) clinically-identified sleep apnea, and 3) cerebrovascular responsiveness to changing CO2. Results: Logistic regression revealed a 7-fold elevated odds of chronic fatigue after SCI [OR: 7.9, 95% CI: 3.5-16.2], and that fatigue and trouble sleeping are correlated with the level and severity of injury. We further show that those with SCI experience elevated risk of clinically-defined sleep-disordered breathing in more than 600 individuals with SCI [pooled OR: 3.1, 95% CI: 1.3-7.5]. We confirmed that individuals with SCI experience a high rate of clinically-defined sleep-apnea using primary polysomnography assessments. We then provide evidence using syndromic analysis that sleep-disordered breathing is a factor strongly associated with impaired cerebrovascular responsiveness to CO2 in patients with SCI. Conclusions: Individuals with SCI have an increased prevalence of sleep-disordered breathing, which may partially underpin their increased risk of stroke. There is thus a need to integrate sleep-related breathing examinations into routine care for individuals with SCI.
Figure 1 from: Melly DK, Kipkoech S, Muema BW, Kamau P, Malombe I, Hu G, Wang Q-F (2020) An annotated checklist of the vascular flora of South and North Nandi Forests, Kenya. PhytoKeys 155: 87-139. https://doi.org/10.3897/phytokeys.155.51966
Figure 1 Location of North and South Nandi forests of Kenya.
Figure 6 from: Jamilah MS, Lee GE, Salam MR, Shahimi S, Pesiu E, Jani JM, Horsali NAI, Shahrudin R, Nor SMM, Chong JL, Mohamad F, Raffi A, Nikong D (2020) A checklist of vascular plants and uses of some species for livelihood-making in Setiu Wetlands, Terengganu, Malaysia. PhytoKeys 160: 7-43. https://doi.org/10.3897/phytokeys.160.52946
Figure 6 Number of various wild flora species users according to villages.
Figure 7 from: Jamilah MS, Lee GE, Salam MR, Shahimi S, Pesiu E, Jani JM, Horsali NAI, Shahrudin R, Nor SMM, Chong JL, Mohamad F, Raffi A, Nikong D (2020) A checklist of vascular plants and uses of some species for livelihood-making in Setiu Wetlands, Terengganu, Malaysia. PhytoKeys 160: 7-43. https://doi.org/10.3897/phytokeys.160.52946
Figure 7 Number of producers based on type of products made from wild flora.
Figure 3 from: Jamilah MS, Lee GE, Salam MR, Shahimi S, Pesiu E, Jani JM, Horsali NAI, Shahrudin R, Nor SMM, Chong JL, Mohamad F, Raffi A, Nikong D (2020) A checklist of vascular plants and uses of some species for livelihood-making in Setiu Wetlands, Terengganu, Malaysia. PhytoKeys 160: 7-43. https://doi.org/10.3897/phytokeys.160.52946
Figure 3 The 12 largest families and genera of the vascular plants of Setiu Wetlands.
Figure 2 from: Jamilah MS, Lee GE, Salam MR, Shahimi S, Pesiu E, Jani JM, Horsali NAI, Shahrudin R, Nor SMM, Chong JL, Mohamad F, Raffi A, Nikong D (2020) A checklist of vascular plants and uses of some species for livelihood-making in Setiu Wetlands, Terengganu, Malaysia. PhytoKeys 160: 7-43. https://doi.org/10.3897/phytokeys.160.52946
Figure 2 The locality of Setiu Wetlands and the nine vegetation types.
Figure 1 from: Kiew R, Chung-Lu L (2020) Checklist of vascular plants of Klang Gates Quartz Ridge, Malaysia, a 14-km long quartz dyke. PhytoKeys 166: 57-77. https://doi.org/10.3897/phytokeys.166.55778
Figure 1 Rhodoleia championii, one of the dominant tree species on the summit.
VEGFA dependent endothelial lumen formation in scaffold-free tissue engineering: a hybrid in vitro and in silico approach to improve vascularization of tissue: Spheroid simulation data
<p>Vascularization is a tightly regulated process involving a complex interplay of multiple bio-signaling events. Among these events, lumen formation is a crucial rate-limiting step in successful anastomosis of tissue engineered constructs in a host. We have developed scaffold-free endothelial-fibroblast based constructs with preformed microvessel networks that are a promising approach to rapid host-implant anastomosis. However, rapid formation of a continuous endothelial lumen within the microvessels remains elusive. We propose that pretreatment of these constructs with vascular endothelial growth factor A, a potent proangiogenic molecule, can improve large caliber lumen formation within constructs during <i>in vitro</i> self-assembly.</p> <p>Here, we present a hybrid <i>in vitro </i>and <i>in silico </i>approach to evaluating endothelial-fibroblast spheroid self-assembly and the effects of VEGF-A on lumen formation. Our VEGF-A dosing experiments ultimately demonstrated that our endothelial cells responded to VEGF-A by increased clustering tendency and hollow lumen formation. This behavior was coincident with an increase in polarization markers as well as a time and dose dependent increase in diameter of lumens. We used these observations to develop a simulation model using the Cellular Potts framework, a modeling framework that is well-adapted to tissue self-assembly. The model explores how changes in interfacial energy costs between cell types in our model as well as changes in basic cell parameters such as response to VEGF-A, growth and proliferation can alter dynamics of lumen formation within a construct. From our model, we ran a series of simulated experiments to generate tissues with an optimal distribution of large caliber vessels. Our analysis of the resulting regression model identified several statistically significant modifiable factors that could be mapped back to potential spheroid pretreatment strategies. These strategies could augment VEGF-mediated lumen formation and provide rationale for alterations in the design of our constructs.</p>
Figure 4 from: Márquez-García F, García-Alonso D, Guerra-Barrena MJ, Vázquez-Pardo FM (2021) Vascular plants dataset of the herbarium (HSS) of Agrarian Research Institute Finca "La Orden-Valdesequera" (CICYTEX), Extremadura, Spain. PhytoKeys 171: 47-59. https://doi.org/10.3897/phytokeys.171.58900
Figure 4 Number of specimens collected between 1990 and 2020.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.