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544
datasets available to search
ShareScore release 0.9.0
Dataset results
544 results for “Metabolic Diseases”
Testing the contribution of FGL1 to the pathogenesis of metabolic dysfunction-associated steatotic liver disease and hepatocellular carcinoma
GEO Series GSE291163. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Energy-sensing molecule RORγ regulates Cholesterol Metabolism and Immune Signaling in Diabetic Kidney Disease and Aging
GEO Series GSE317266. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
A temporal proteogenomic atlas of HCV-host interactions unravels cell circuits driving viral and metabolic liver disease.
GEO Series GSE126831. Homo sapiens. 63 samples. Type: Expression profiling by high throughput sequencing.
Extensive reprogramming of lipid metabolism in the liver during West Nile virus infection in mice highlights novel aspects of disease pathophysiology [liver]
GEO Series GSE242980. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Alzheimer’s, Parkinson’s disease and Amyotrophic Lateral Sclerosis gene expression patterns divergence reveals different grade of RNA metabolism involvement
GEO Series GSE161199. Homo sapiens. 23 samples. Type: Expression profiling by high throughput sequencing.
Liver TET1 promotes metabolic dysfunction-associated steatotic liver disease
GEO Series GSE286394. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Induction ofsteatosis in primary human hepatocytes manifests into hepatic pathophysiology of metabolic dysfunction-associated liver disease
GEO Series GSE247407. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.
Deficiency of ADAR2 ameliorates metabolic-associated fatty liver disease via AMPK signaling pathways in obese mice
GEO Series GSE261185. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) [RNA-s
GEO Series GSE238201. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide CRISPR/Cas9 library screening identified OGDH as a regulator of disease progress and HMAs-resistance in MDS by reprogramming glutamine metabolism
GEO Series GSE273914. Homo sapiens. 5 samples. Type: Other.
A Novel Alzheimer's Disease Drug Candidate Targeting Inflammation and Fatty Acid Metabolism
GEO Series GSE93678. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.
P21+TREM2+-Senescent Macrophages Fuel Inflammaging and Metabolic Dysfunction-Associated Steatotic Liver Disease [RNAseq_MASHABT263]
GEO Series GSE318652. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Untargeted LC-HRMS-based metabolomic profiling reveals distinct metabolomic profiles in patients with metabolic dysfunction-associated steatotic liver disease (MASLD)
<p>We analyzed liver tissues, liver secretome (conditioned medium), and blood plasma samples from 109 obese patients undergoing bariatric surgery spanning early stages of metabolic dysfunction-associated steatotic liver diseases (MASLD). We used a combination of data-dependent acquisition (DDA) and data-independent acquisition (DIA or SWATH-MS) on SCIEX TripleTOF 6600,</p> <p>Metabolites and lipids were extracted using modified chloroform-methanol biphasic extraction methods for both biological matrices. Organic and aqueous fractions were separated using RRHD Eclipse Plus C18 and SeQuant ZIC-cHILIC columns prior to DDA and DIA acquisitions, respectively.</p> <p>All mzML files are deposited with ZENODO.</p> <p> </p> <p>*** DDA files are deposited in this dataset repository ***</p> <p><strong>Child directories for SWATH data files</strong></p> <table> <tbody> <tr> <td>Samples</td> <td>Polarity</td> <td>Zenodo DOI</td> </tr> <tr> <td>Organic fraction - Reverse Phase</td> <td>Positive & Negative</td> <td> <p>10.5281/zenodo.14096635</p> </td> </tr> <tr> <td>Aqueous fraction - HILIC</td> <td>Positive</td> <td> <p>10.5281/zenodo.14096753</p> </td> </tr> <tr> <td>Aqueous fraction - HILIC</td> <td>Negative</td> <td> <p>10.5281/zenodo.14136832</p> </td> </tr> </tbody> </table> <p> </p>
Development of a Non-invasive Screening Tool to Predict Metabolic Dysfunction-associated Steatotic Liver Disease
ClinicalTrials.gov study NCT04873258. IPD Sharing: NO. Countries: 1. Publications: 0.
The Effects of Glucocorticoids on Glucose Metabolism in Patients With Interstitial Lung Disease
ClinicalTrials.gov study NCT02824757. IPD Sharing: YES. Countries: 1. Publications: 0.
Drug Metabolizing Enzyme and Transporter Function in Chronic Kidney Disease
ClinicalTrials.gov study NCT02360644. IPD Sharing: NO. Countries: 1. Publications: 0.
Digital Diet and Exercise Intervention to Reduce Liver Fibrosis in Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)
ClinicalTrials.gov study NCT06920316. IPD Sharing: NO. Countries: 1. Publications: 0.
Metabolic Workup in Patients Suffering From Kidney Stone Disease and Osteopenia
ClinicalTrials.gov study NCT04080973. IPD Sharing: NO. Countries: 1. Publications: 0.
Mechanisms of Exercise Resistance in Metabolic Disease
ClinicalTrials.gov study NCT03945435. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Runihol in Nonalcoholic Fatty Liver Disease and Metabolic Syndrome
ClinicalTrials.gov study NCT02930161. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.