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272
datasets available to search
ShareScore release 0.9.0
Dataset results
272 results for “endothelium”
Shock drives a highly coordinated transcriptional and DNA methylation response in the endothelium_DNA methylation
GEO Series GSE223381. Homo sapiens. 21 samples. Type: Methylation profiling by genome tiling array.
Transcriptomic analysis of iPSC-derived endothelium reveals adaptations to high altitude hypoxia in energy metabolism and inflammation
GEO Series GSE280017. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Identification of Circulating Fibrocytes and Dendritic Derivatives in Corneal Endothelium of Patients with Fuchs' Dystrophy [microarray expression analysis]
GEO Series GSE74123. Homo sapiens. 8 samples. Type: Expression profiling by array.
Human endothelium exposed to shear stress and pressure
GEO Series GSE1518. Homo sapiens. 8 samples. Type: Expression profiling by array.
Scl Represses Cardiomyogenesis in Prospective Hemogenic Endothelium and Endocardium
GEO Series GSE27445. Mus musculus. 24 samples. Type: Expression profiling by array.
The human aortic endothelium undergoes dose-dependent DNA methylation in response to transient hyperglycemia
GEO Series GSE163510. Homo sapiens. 6 samples. Type: Methylation profiling by high throughput sequencing.
Mesp1 induces a subset of hematopoietic-associated transcription factors in ES cell-derived Flk1+Tie2+ endothelium
GEO Series GSE34537. Mus musculus. 2 samples. Type: Expression profiling by array.
Prevention of acute thrombosis with vascular endothelium antioxidative nanoscavenger
GEO Series GSE307563. Rattus norvegicus. 8 samples. Type: Expression profiling by high throughput sequencing.
Bulk RNA-sequencing of CD49fHigh and CD49fLow populations from hESCs-derived HSPCs and Hemogenic Endothelium
GEO Series GSE151129. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome characterization of venous endothelium during the formation of neointimal hyperplasia and stenosis in a rat arteriovenous fistula model for kidney dialysis
GEO Series GSE46126. Rattus norvegicus. 17 samples. Type: Expression profiling by array.
kallikrein-related peptidase 8 inhibition protects the pulmonary endothelium during endotoxemic lung injury
GEO Series GSE216969. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Shear Stress and NOTCH1 Regulate Calcification Related Genes in Human Aortic Valve Endothelium (RNA-Seq)
GEO Series GSE47157. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
IL6 Related Cytokines Augment Angiogenesis in Nascent and Mature Human Endothelium Via JAK2 Signaling
GEO Series GSE44328. Homo sapiens. 7 samples. Type: Expression profiling by array.
Hematopoietic cells emerging from hemogenic endothelium exhibit lineage-specific oxidative stress responses
GEO Series GSE270141. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Mediator 1 Regulation of the BMP/TGF-b Signaling in Endothelium: Implications for Pulmonary Hypertension
GEO Series GSE212816. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNAseq analysis of pericyte-deficient endothelium
GEO Series GSE146007. Mus musculus. 1187 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide analysis of human endothelium response to Staphylococcus aureus blood isolates infection.
GEO Series GSE82036. Homo sapiens. 24 samples. Type: Expression profiling by array.
Gene expression profiles of endothelium, microglia and oligodendrocytes in hippocampus of post-stroke depression rat at single cell resolution
GEO Series GSE232936. Rattus norvegicus. 4 samples. Type: Expression profiling by high throughput sequencing.
GATA2 is Dispensable for Generation of Hemogenic Endothelium But Required for Endothelial-to-Hematopoietic Transition
GEO Series GSE102767. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "mTOR-Dependent Stimulation of IL20RA Orchestrates Immune Cell Trafficking through Lymphatic Endothelium in Patients with Crohn's Disease."
<p>Crohn's disease (CD) is a chronic inflammatory condition that can affect different portions of the gastrointestinal tract. Lymphatic drainage was demonstrated to be dysfunctional in CD pathogenesis, ultimately causing the failure of the resolution of intestinal inflammation. To investigate the molecular mechanisms underlying these dysfunctions, we isolated human intestinal lymphatic endothelial cells (HILECs) from surgical specimens of patients undergoing resection for complicated CD (CD HILEC) and from a disease-free margin of surgical specimens of patients undergoing resection for cancer (healthy HILEC). Both cell types underwent transcriptomic profiling, and their barrier functionality was tested using a transwell-based co-culture system between HILEC and lamina propria mononuclear cells (LPMCs). Results showed CD HILEC displayed a peculiar transcriptomic signature that highlighted mTOR signaling as an orchestrator of leukocyte trafficking through the lymphatic barrier of CD patients. Moreover, we demonstrated that LPMC transmigration through the lymphatic endothelium of patients with CD depends on the capability of mTOR to trigger interleukin 20 receptor subunit α (IL20RA)-mediated intracellular signaling. Conclusively, our study suggests that leukocyte trafficking through the intestinal lymphatic microvasculature can be controlled by modulating IL20RA, thus leading to the resolution of chronic inflammation in patients with CD.</p>
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.