Skip to main content
Powered by ShareScore

Find research datasets worth reusing

Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.

3,139

datasets available to search

ShareScore release 0.9.0

Reset

Dataset results

3,139 results for “fitting”

Learn how ShareScore rates datasets ↗
dryad36/100

Detritus decorations as the extended phenotype deflect avian predator attack increasing fitness in an orb‐web spider

<ol> <li>A number of strategies that divert attacks of visually guided predators, such as birds, have evolved multiple times in animals. Detritus web decorations built by certain orb-web spider species are thought to deflect avian predator attacks away from spiders and towards their web decorations. Still, empirical evidence for this function and its adaptive significance is lacking. The orb-web spider, <i>Cyclosa monticola</i>,<i> </i>adorns its web using a linear detritus decoration consisting of moults, egg sacs, prey remains, and leaf litters.</li> <li>In the present study, we investigated whether detritus decorations constructed by <i>C. monticola</i> spiders<i> </i>divert attacks of avian predators away from spiders. We first employed colour modelling to compare spider bodies and detritus decoration colouration from the perspective of domestic chicks and blue tits. We then experimentally tested the deflection hypothesis in the laboratory using naïve chicks as predators. We put the chicks in a cage containing a web either with (S+) or without (S-) a spider and either with (D+) or without (D-) detritus decoration (a total of four types of webs: S+D+, S+D-, S-D+, and S-D-) under both natural habitat background and white background. </li> <li>We found that the colour of <i>C. monticola</i> spiders is indistinguishable from that of their detritus decorations for both chicks and blue tits with both backgrounds. Laboratory predation experiments showed that with both backgrounds, chicks attacked the spiders much less frequently when their decorations were present on the webs (S+D+; natural habitat: 20%, white background: 30%) than when their decorations were absent (S+D-; natural habitat: 95%, white background: 85%), resulting in greater spider survival advantage. </li> <li>We also found that the rate of attack of spiders and their decorations was not random; the decorations were more likely to be attacked than spiders, regardless of the ratio of surface area of decorations to spider bodies when both spiders and decorations were presented (S+D+). Therefore, our results support a deflection, rather than concealment hypothesis for web decorations.</li> <li>In conclusion, our study provides evidence that the extended phenotypes beyond the animal bodies, can divert avian predator attacks, therefore, may improve the fitness of animals.</li> </ol>

opencc-zeroAug 2020View details →
dryad36/100

Data S1. Laboratory behavioral data from: Measuring the fitness advantage conferred by autotomy in the wild

<p>Data S1. Laboratory behavioral data. The composition is summarized in figure S1.</p> <p>Autotomy, the self-amputation of body parts, serves as an anti-predator defense in many taxonomic groups of animals. However, its adaptive value has seldom been quantified. Here, we propose a novel modeling approach for measuring the fitness advantage conferred by the capability for autotomy in the wild. Using a predator-prey system where a land snail autotomizes and regenerates its foot specifically in response to snake bites, we conducted a laboratory behavioral experiment and a 3-year multi-event capture–mark–recapture (CMR) study. Combining these empirical data, we developed a hierarchical model and estimated the basic life history parameters of the snail. Using samples from the posterior distribution, we constructed the snail's life table as well as that of a snail variant incapable of foot autotomy. As a result of our analyses, we estimated the monthly encounter rate with snake predators at 3.3% (95% CI: 1.6–4.9%), the contribution of snake predation to total mortality until maturity at 43.3% (15.0–95.3%), and the fitness advantage conferred by foot autotomy at 6.5% (2.7–11.5%). This study demonstrated the utility of the multi-method hierarchical modeling approach for the quantitative understanding of the ecological and evolutionary processes of anti-predator defenses in the wild.</p>

opencc-zeroAug 2020View details →
dryad36/100

Data S2. CMR data from: Measuring the fitness advantage conferred by autotomy in the wild

<p>Data S2. CMR data. The composition is summarized in tables S2, S3, and S10.</p> <p>Autotomy, the self-amputation of body parts, serves as an anti-predator defense in many taxonomic groups of animals. However, its adaptive value has seldom been quantified. Here, we propose a novel modeling approach for measuring the fitness advantage conferred by the capability for autotomy in the wild. Using a predator-prey system where a land snail autotomizes and regenerates its foot specifically in response to snake bites, we conducted a laboratory behavioral experiment and a 3-year multi-event capture–mark–recapture (CMR) study. Combining these empirical data, we developed a hierarchical model and estimated the basic life history parameters of the snail. Using samples from the posterior distribution, we constructed the snail's life table as well as that of a snail variant incapable of foot autotomy. As a result of our analyses, we estimated the monthly encounter rate with snake predators at 3.3% (95% CI: 1.6–4.9%), the contribution of snake predation to total mortality until maturity at 43.3% (15.0–95.3%), and the fitness advantage conferred by foot autotomy at 6.5% (2.7–11.5%). This study demonstrated the utility of the multi-method hierarchical modeling approach for the quantitative understanding of the ecological and evolutionary processes of anti-predator defenses in the wild.</p>

opencc-zeroAug 2020View details →
dryad36/100

Herbivory Improves the Fitness of Predatory Beetles

<p>While many predatory arthropods consume non-prey foods from lower trophic levels, little is known about what drives the shift from predator to omnivore. Predatory lady beetles often consume non-prey foods like plant foliage and pollen. One species, Coccinella septempunctata, eats foliage to redress sterol deficits caused by eating sterol-deficient prey. Here we explore how omnivory benefits lady beetle fitness.</p> <p>We reared seven species of lady beetles – from five genera distributed across the tribe Coccinellini – on pea aphids in the presence or absence of fava bean foliage; pea aphids have very low sterol content. Foliage supplements lengthened the development times of four species and decreased survival to adulthood of two species; it had no effect on adult mass. We mated beetles in a 2x2 factorial design (males with or without foliage paired with females with or without foliage). For each species, we observed a profound paternal effect of foliage supplements on fitness. Females mated to foliage-supplemented males laid more eggs and more viable eggs compared to females mated to non-supplemented males. Foliage-supplemented males produced 2.9–4.6 times more sperm compared to non-supplemented males for the three species examined.</p> <p>We analyzed the sterol profile of four beetle species reared on pea aphids – with or without foliage – and compared their sterol profile to field-collected adults. For two lab-reared species, sterols were not detected in adult male beetles, and overall levels were generally low (total ng of sterol/beetle range: 3-33 ng); the exception being P. quatuordecimpunctata females (total ng of sterol/beetle range: 50-157 ng). Laboratory-reared lady beetle sterol content was not significantly affected by the presence of foliage. Field-collected beetles had higher levels of sterols compared to lab-reared beetles (2,452–145,348 ng per beetle); cholesterol and sitosterol were the dominant sterols in field-collected and lab-reared beetles.</p> <p>Our findings indicate that herbivory benefits lady beetle fitness across the Coccinellini, and that this was entirely a paternal effect. Our data provides a rare example of a nutritional constraint impacting fitness in a sex-specific manner. It also shows, more broadly, how a nutritional constraint can drive predators toward omnivory. 17-Jul-2020</p>

opencc-zeroAug 2020View details →
dryad36/100

Data from: Behavioural and fitness effects of translocation to a novel environment: whole-lake experiments in two aquatic top predators

<p>Translocation into a novel environment through common fisheries-management practices, such as fish stocking, provides opportunities to study behavioural and fitness impacts of translocations at realistic ecological scales. The process of stocking, as well as the unfamiliarity with novel ecological conditions and the interactions with resident fish may affect translocated individuals, leading to alterations of behaviours and causing fitness impacts.</p> <p>Our objectives were to investigate how aquatic top-predators behaviourally establish themselves and compete with resident individuals following introduction in a novel lake environment and to investigate the resulting fitness consequences.</p> <p>Using high-resolution acoustic telemetry, we conducted whole-lake experiments and compared the activity, activity-space size and fate of translocated and resident individuals in two model top predators, northern pike (Esox lucius, n = 160) and European catfish (Silurus glanis, n = 33). Additionally, we compared the reproductive fitness of translocated and resident northern pike. The experiment was conducted with large (adult) individuals of different origins, resilient to predation, but subject to agonistic interactions and competition with resident fish.</p> <p>Over a period of several months, the translocated catfish exhibited consistently larger activity-space sizes than resident catfish, but did not differ from residents in activity and survival. The pike from one of the two translocated origins we tested also showed elevated space-use, and both translocated origins revealed higher mortality rates than their resident conspecifics, indicating maladjustment to their novel environment. When non-resident pike reproduced, they overwhelmingly produced hybrid offspring with resident fish, indicating that introductions fostered gene flow of non-native genes.</p> <p>Our study indicates that fish introductions result in behavioural and fitness impacts even in large-bodied top predators that experience low levels of natural predation risk. </p>

opencc-zeroAug 2020View details →
dryad36/100

Data from: Genome duplication effects on functional traits and fitness are genetic context and species dependent: studies of synthetic polyploid Fragaria

PREMISE OF THE STUDY Divergence in functional traits and adaptive responses to environmental change underlies the ecological advantage of polyploid plants in the wild. While established polyploids may benefit from combined outcomes of genome doubling, hybridization and polyploidy-enabled adaptive evolution, it remains less clear whether genome doubling alone can drive ecological divergence or whether the outcome is genetically variable.METHODS Using synthetic, colchicine-induced, autotetraploid (4x) plants derived from self-pollinated diploid (2x) seeds, and their colchicine-treated but unconverted diploid (2x.nc) full sibs from two diploid wild strawberry taxa (Fragaria vesca ssp. vesca and F. vesca ssp. bracteata), we examined the effects of genome doubling on functional traits, heat stress tolerance and fitness components across taxa and maternal families (i.e. genetic families) within taxa.KEY RESULTS Comparisons between 2x and 2x.nc plants indicated a negligible effect of colchicine treatment on functional traits. Genome doubling increased stomatal length, and decreased stomatal density, specific leaf area and leaf vein density, recapitulating patterns observed in wild polyploid Fragaria. Trichome density, heat stress tolerance and relative growth rate were not significantly affected by genome doubling. Although a reduction in clonal reproduction was observed in response to genome doubling, this effect was strongly genetic family dependent.CONCLUSIONS The results suggest that genome doubling during incipient speciation alone can generate ecological divergence and variation among genetic lineages. This response potentially allows for rapid short-term evolutionary adaptation and fuels genomic diversity and independent origins of polyploidy.

opencc-zeroSep 2020View details →
dryad36/100

Identifying the fitness consequences of sex in complex natural environments

In the natural world, sex prevails, despite its costs. While much effort has been dedicated to identifying the intrinsic costs of sex (e.g. the cost of males), few studies have identified the ecological fitness consequences of sex. Furthermore, correlated biological traits that differ between sexuals and asexuals may alter these costs, or even render the typical costs of sex irrelevant. We conducted a large-scale multi-site reciprocal transplant using multiple sexual and asexual genotypes of a native North American wildflower to show that sexual genotypes have reduced lifetime fitness, despite lower herbivory. We separated the effects of sex from those of hybridity, finding that over-winter survival is elevated in asexuals regardless of hybridity, but herbivores target hybrid asexuals more than non-hybrid asexual or sexual genotypes. Survival is lowest in homozygous sexual lineages, implicating inbreeding depression as a cost of sex. Our results show that the consequences of sex are shaped not just by sex itself, but by complex natural environments, correlated traits, and the identity and availability of mates.

opencc-zeroSep 2020View details →
dryad36/100

Data from: Low fitness at low latitudes: wintering in the tropics increases migratory delays and mortality rates in an arctic-breeding shorebird

<p>1. Evolutionary theories of seasonal migration generally assume that the costs of longer migrations are balanced by benefits at the non-breeding destinations. 2. We tested, and rejected, the null hypothesis of equal survival and timing of spring migration for High Arctic breeding sanderling Calidris alba using six and eight winter destinations between 55° N and 25° S, respectively. 3. Annual apparent survival was considerably lower for adult birds wintering in tropical West-Africa (Mauritania: 0.74 and Ghana: 0.75) than in three European sites (0.84, 0.84 and 0.87) and in subtropical Namibia (0.85). Moreover, compared with adults, second calendar-year sanderlings in the tropics, but not in Europe, often refrained from migrating north during the first possible breeding season. During northward migration, tropical-wintering sanderlings occurred at their final staging site in Iceland 5-15 days later than birds wintering further north or south. Namibia-wintering sanderlings tracked with solar geolocators only staged in West-Africa during southward migration. 4. The low annual survival, the later age of first northward migration and the later passage through Iceland during northward migration of tropical-wintering sanderlings, in addition to the skipping of this area during northward but not southward migration by Namibia-wintering sanderlings, all suggest they face issues during the late non-breeding season in West-Africa. 5. Migrating sanderlings defy long distances but may end up in winter areas with poor fitness prospects. We suggest that ecological conditions in tropical West-Africa make the fuelling prior to northward departure problematic. </p>

opencc-zeroSep 2020View details →
dryad36/100

Fitness costs of parasites explain multiple life history tradeoffs in a wild mammal

Reproduction in wild animals can divert limited resources away from immune defence, resulting in increased parasite burdens. A longstanding prediction of life history theory states that these parasites can harm the individual, reducing the organism's subsequent fitness and producing reproduction-fitness tradeoffs. Here, we examined associations among reproductive allocation, immunity, parasitism, and subsequent fitness in a wild population of individually identified red deer ( Cervus elaphus ). Using path analysis, we investigated whether costs of lactation for downstream survival and fecundity were mediated by changes in strongyle nematode count and mucosal antibody levels. Lactating females exhibited increased parasite counts, which were in turn associated with substantially decreased fitness in the following year in terms of overwinter survival, fecundity, subsequent calf weight, and parturition date. This study offers observational evidence for parasite regulation of multiple life history tradeoffs, supporting the role of parasites as an important mediating factor in wild mammal populations.

opencc-zeroOct 2020View details →
zenodo36/100

ForceBalance Fitting Tutorial

<p>Video tutorials on how to use ForceBalance in force field fitting procedures used in the Open Force Field Initiative.</p>

opencc-by-4.0Oct 2020View details →
dryad36/100

Long-term effects of antibiotic treatments on honeybee colony fitness – a modelling approach

<p><b>1.</b> Gut microbiome disequilibrium is increasingly <span>implicated </span>in host fitness reductions, including for the economically important and disease-challenged western honey bee, <i>Apis mellifera</i>. In lab experiments the antibiotic tetracycline, which is used to prevent American Foulbrood Disease in countries including the US, elevates honey bee mortality by disturbing the microbiome. It is unclear however, how elevated individual mortality affects colony level fitness.</p> <p><b>2.</b> We used an agent-based model (BEEHAVE) and empirical data to assess colony level effects of antibiotic-induced worker bee mortality, by measuring colony size. We investigated the relationship between the duration that the antibiotic-induced mortality probability is imposed for and colony size.</p> <p><b>3.</b> We found that when simulating antibiotic-induced mortality of worker bees from just 60 days per year, up to a permanent effect, the colony is reduced such that tetracycline treatment would not meet the European Food Safety Authority's (EFSA) honey bee protection goals. When antibiotic mortality was imposed for the hypothetical minimal exposure time, which assumes that antibiotics only impact the bee's fitness during the recommended treatment period of fifteen days in both spring and autumn, the colony fitness reduction was only marginally under the EFSA's threshold.</p> <p><b>4.</b> Synthesis and Applications: Modelling colony level impacts of antibiotic treatment shows that individual antibiotic-induced honey bee worker mortality can lead to colony mortality. To assess the full impact, the persistence of antibiotic-induced mortality in honey bees must be determined experimentally, <i>in vivo</i>. We caution that as the domestication of new insect species increases, maintaining healthy gut microbiomes is of paramount importance to insect health and commercial productivity. The recommendation from this work is to limit prophylactic use of antibiotics and to not exceed recommended treatment strategies for domesticated insects. This is especially important for highly social insects as excess antibiotic use will likely decrease colony growth and an increase in colony mortality.</p>

opencc-zeroOct 2020View details →
dryad36/100

Data from: Fitness outcomes in relation to individual variation in constitutive innate immune function

<p>Although crucial for host survival when facing persistent parasite pressure, costly immune functions will inevitably compete for resources with other energetically expensive traits such as reproduction. Optimising, but not necessarily maximising, immune function might therefore provide net benefit to overall host fitness. Evidence for associations between fitness and immune function is relatively rare, limiting our potential to understand ultimate fitness costs of immune investment. Here, we assess how measures of constitutive immune function (haptoglobin, natural antibodies, complement activity) relate to subsequent fitness outcomes (survival, reproductive success, dominance acquisition) in a wild passerine (<i>Malurus coronatus</i>). Surprisingly, survival probability was not positively linearly predicted by any immune index. Instead, both low and high values of complement activity (quadratic effect) were associated with higher survival, suggesting that different immune investment strategies might reflect a dynamic disease environment. Positive linear relationships between immune indices and reproductive success suggest that individual heterogeneity overrides potential resource reallocation trade-offs within individuals. Controlling for body condition (size-adjusted body mass) and chronic stress (heterophil-lymphocyte ratio) did not alter our findings in a sample subset with available data. Overall, our results suggest that constitutive immune components have limited net costs for fitness and that variation in immune maintenance relates to individual differences more closely.</p>

opencc-zeroNov 2020View details →
dryad36/100

Trait-fitness associations do not predict within-species phenotypic evolution over 2 million years

Long-term patterns of phenotypic change are the cumulative results of tens of thousands to millions of years of evolution. Yet, empirical and theoretical studies of phenotypic selection are largely based on contemporary populations. The challenges in studying phenotypic evolution, in particular trait-fitness associations in the deep past, are barriers to linking micro- and macroevolution. Here, we capitalize on the unique opportunity offered by a marine colonial organism commonly preserved in the fossil record to investigate trait-fitness associations over 2 million years. We use the density of female polymorphs in colonies of <em>Antartothoa tongima</em> as a proxy for fecundity, a fitness component, and investigate multivariate signals of trait-fitness associations in six time intervals on the backdrop of Pleistocene climatic shifts. We detect negative trait-fitness associations for feeding polymorph (autozooid) sizes, positive associations for autozooid shape but no particular relationship between fitness and brood chamber size. In addition, we demonstrate that long-term trait patterns are explained by palaeoclimate and to a lesser extent by ecological interactions. Our analyses show that macroevolutionary outcomes of trait evolution are not a simple scaling-up from the trait-fitness associations.

opencc-zeroJan 2021View details →
dryad36/100

Sensory pollutants alter bird phenology and fitness across a continent

<p>Expansion of anthropogenic noise and night-lighting across our planet is of increasing conservation concern Despite growing knowledge of physiological and behavioural responses to these stimuli from single-species and local-scale studies, whether these pollutants affect fitness is less clear, as is how and why species vary in their sensitivity to these anthropic stressors. Here, we leverage a large citizen science dataset paired with high-resolution noise and light data from across the contiguous United States to assess how these stimuli affect reproductive success in 142 bird species. We find responses to both sensory pollutants linked to the functional traits and habitat affiliations of species. For example, overall nest success was negatively correlated with noise among birds in closed environments. Species-specific changes in reproductive timing and hatching success in response to noise exposure were explained by vocalization frequency, nesting location and diet. Additionally, increased light-gathering ability of species' eyes was associated with stronger advancements in reproductive timing in response to light exposure, potentially creating phenological mismatches. Unexpectedly, better light-gathering ability was linked to reduced clutch failure and increased overall nest success in response to light exposure, raising important questions about how responses to sensory pollutants counteract or exacerbate responses to other aspects of global change, such as climate warming. These findings demonstrate that anthropogenic noise and light can substantially affect breeding bird phenology and fitness, and underscore the need to consider sensory pollutants alongside traditional dimensions of the environment that typically inform biodiversity conservation.</p>

opencc-zeroNov 2020View details →
dryad36/100

Data from: The repeatable opportunity for selection differs between pre- and post-copulatory fitness components

<p>In species with multiple mating, intense sexual selection may occur both before and after copulation. However, comparing the strength of pre- and postcopulatory selection is challenging, because i) postcopulatory processes are generally difficult to observe and ii) the often-used opportunity for selection (<i>I</i>) metric contains both deterministic and stochastic components. Here, we quantified pre- and postcopulatory male fitness components of the simultaneously hermaphroditic flatworm, <i>Macrostomum lignano</i>. We did this by tracking fluorescent sperm—using transgenics—through the transparent body of sperm recipients, enabling to observe postcopulatory processes <i>in vivo</i>. Moreover, we sequentially exposed focal worms to three independent mating groups, and in each assessed their mating success, sperm-transfer efficiency, sperm fertilising efficiency, and partner fecundity. Based on these multiple measures, we could, for each fitness component, combine the variance (<i>I</i>) with the repeatability (<i>R</i>) in individual success to assess the amount of repeatable variance in individual success—a measure we call the repeatable opportunity for selection (<i>I<sub>R</sub></i>). We found higher repeatable opportunity for selection in sperm-transfer efficiency and sperm fertilising efficiency compared to mating success, which clearly suggests that postcopulatory selection is stronger than precopulatory selection. Our study demonstrates that the opportunity for selection contains a repeatable deterministic component, which can be assessed and disentangled from the often large stochastic component, to provide a better estimate of the strength of selection.</p>

opencc-zeroNov 2020View details →
dryad36/100

Data from: Heterozigosity-fitness correlations in a continental island population of Thorn-tailed Rayadito

<p>Heterozygosity-fitness correlations (HFCs) have been used to monitor the effects of inbreeding in threatened populations. HFCs can also be useful to investigate the potential effects of inbreeding in isolated relict populations of long-term persistence, and to better understand the role of inbreeding and outbreeding as drivers of changes in genetic diversity. We studied a continental island population of thorn-tailed rayadito (<i>Aphrastura spinicauda</i>) inhabiting the relict forest of Fray Jorge National Park, north-central Chile. This population has experienced a long-term, gradual process of isolation since the end of the Tertiary. Using 10 years of field data in combination with molecular techniques, we tested for HFCs to assess the importance of inbreeding depression. If inbreeding depression is important, we predict a positive relationship between individual heterozygosity and fitness-related traits. We genotyped 183 individuals at 12 polymorphic microsatellite loci, and used seven measures of reproductive success and estimates of apparent survival to calculate HFCs. We found weak to moderate statistical support (<i>P</i>-values between 0.05 and 0.01) for a linear effect of female multi-locus heterozygosity (MLH) on clutch size, and non-linear effects on laying date and fledging success. While more heterozygous females laid smaller clutches, non-linear effects indicated that females with intermediate values of MLH started laying earlier and had higher fledging success. We found no evidence for effects of MLH on annual fecundity or on apparent survival. Our results along with the long-term demographic stability of the study population contradict the hypothesis that inbreeding depression occurs in this population.</p>

opencc-zeroDec 2020View details →
zenodo36/100

The repeatable opportunity for selection differs between pre- and postcopulatory fitness components

<p>Mating movies and sperm movies of the flatworm <em>Macrostomum lignano</em> supporting the article &quot;The repeatable opportunity for selection differs between pre- and postcopulatory fitness components&quot; published in Evolution Letters.</p>

opencc-by-4.0Nov 2020View details →
dryad36/100

Indirect parental effects on offspring fitness by egg-derived fluids in an external fertiliser

<p>The capacity for parents to influence offspring phenotypes via nongenetic inheritance is currently a major area of focus in evolutionary biology. Intriguing recent evidence suggests that sexual interactions among males and females, both before and during mating, are important mediators of such effects. Sexual interactions typically extend beyond gamete release, involving both sperm and eggs, and their associated fluids. However, the potential for gamete-level interactions to induce transgenerational parental effects remains under-investigated. Here, we test for such effects using an emerging model system for studying gamete interactions, the external fertiliser Mytilus galloprovincialis. We employed a split-ejaculate design to test whether exposing sperm to egg-derived chemicals (ECs) from one female would affect fertilisation rate and offspring survival when those sperm were used to fertilise a different female's eggs. We found significant and separate effects of ECs from non-fertilising females on both fertilisation rate and offspring survival. The offspring survival effect indicates that EC-driven interactions can have transgenerational implications for offspring fitness independent of the genotypes inherited by those offspring. These findings provide a rare test of indirect parental effects driven exclusively by gamete-level interactions, and to our knowledge the first evidence that such effects occur via the gametic fluids of females.</p>

opencc-zeroDec 2020View details →
zenodo36/100

The TEI, Its Foundations and Impact, and How It Fits Into Today's Needs and Practices for Language Analysis

<p>6<sup>th</sup> Lecture</p>

opencc-by-4.0Jul 2018View details →
dryad36/100

Fitness maps to a large-effect locus in introduced stickleback populations

<p>Mutations of small effect underlie most adaptation to new environments, but beneficial variants with large fitness effects are expected to contribute under certain conditions. Genes and genomic regions having large effects on phenotypic differences between populations are known from numerous taxa, but fitness effect sizes have rarely been estimated. We mapped fitness over a generation in an F2 intercross between a marine and a lake stickleback population introduced to a freshwater pond. A QTL map of the number of surviving offspring per F2 female detected a single, large-effect locus near <i>Ectodysplasin</i> (<i>Eda</i>), a gene having an ancient freshwater allele causing reduced bony armor and other changes. F2 females homozygous for the freshwater allele had twice the number of surviving offspring as homozygotes for the marine allele, producing a large selection coefficient, <i>s</i> = 0.50 ± 0.09 SE. Correspondingly, the frequency of the freshwater allele increased from 0.50 in F2 mothers to 0.58 in surviving offspring. We compare these results to observed allele frequency changes at the <i>Eda</i> gene in an Alaskan lake population colonized by marine stickleback in the 1980's. The frequency of the freshwater <i>Eda</i> allele rose steadily over multiple generations and reached 95% within 20 years, yielding a similar estimate of selection, <i>s</i> = 0.49 ± 0.05. These findings are consistent with other studies suggesting strong selection on this gene (and/or linked genes) in fresh water. Selection on ancient genetic variants carried by colonizing ancestors is likely to increase the prevalence of large-effect fitness variants in adaptive evolution.</p>

opencc-zeroDec 2019View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

ScienceDex for faculty

Your academic CV and NIH biosketch

Make your CV in your school's format and your NIH biosketch from it, then download both as Word files.