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54,099 results for “Expression”
Computational Analysis, In silico Functional Annotation, and Expression of Recombinant Mycobacterium PE_PGRS Protein Biomarkers
<p>Data set for bioinformatics predictions and expression profiles.</p> <p> </p>
The pain hidden in your hands: facial expression of pain reduces the influence of goal-related information in action recognition
<p>data and code associated to manuscript entitled "The pain hidden in your hands: facial expression of pain reduces the influence of goal-related information in action recognition"</p>
Transposons are a major contributor to gene expression variability under selection in rice populations
<p>Dataset and code related to the publication: </p> <p>Castanera R., Morales-Díaz N., Gupta S., Purugganan M., Casacuberta JM (2022). Transposons are a major contributor to gene expression variability under selection in rice populations. Research Square. https://doi.org/10.21203/rs.3.rs-2197876/v1. </p> <p><br> 1) TIP_data folder: </p> <p>INDICA_teinsertions_5_2_2_matrix_sorted_ID_MAF003.txt: TIP matrix used for TIP-eQTL mapping (binary form, where 0 = absence, 1= presence)<br> INDICA_teinsertions_5_2_2_matrix_sorted_ID_MAF003.info: TIP information (chrom,start,superfamily,family,maf)<br> JAPONICA_teinsertions_5_2_2_matrix_sorted_ID_MAF003.txt: TIP matrix used for TIP-eQTL mapping (binary form, where 0 = absence, 1= presence)<br> JAPONICA_teinsertions_5_2_2_matrix_sorted_ID_MAF003.info:TIP information (chrom,start,superfamily,family,maf)</p> <p><br> 2) SNP_data folder: </p> <p>SNP_matrix_final_IRGC_Indica_MAF003.lfmm: SNP binary matrix used for TIP-eQTL mapping <br> SNP_matrix_final_IRGC_Indica_MAF003.info: SNP information<br> SNP_matrix_final_IRGC_japonica_MAF003.lfmm: SNP binary matrix used for TIP-eQTL mapping <br> SNP_matrix_final_IRGC_japonica_MAF003.info:SNP information</p> <p>3) Expression data: </p> <p>Normalized expression data and accessory files used for TIP-eQTL analysis (as described in TIP-eQTL_matrix.R)</p> <p>Code:</p> <p>PopoolationTE2.sh: Bash script to reproduce PopoolationTE2 analysis (TIP detection)</p> <p>TIP-eQTL_matrix.R: R code to reproduce eQTL analyses</p> <p> </p>
Confronting false discoveries in single-cell differential expression
<p>A repository containing 18 benchmarking datasets for single-cell method development.</p>
Astrocytic Expression of Yes-Associated Protein (YAP) Regu-lates Retinal Neovascularization in a Mouse Model of Oxy-gen-Induced Retinopathy
<p>Original images used for each figure.</p>
Alzheimer's disease-induced phagocytic microglia express specific profile of coding and non-coding RNAs
<p>This repository contains the data and the code used in Flavia's project.</p> <p>A folder can contain the starting raw data in "data", the R scripts in order of execution (op1, op2 ..) and the "output" folder that contains the final processed data of each operation.</p> <ul> <li>"BV2_analysis" contains the processing and analysis of the bulk RNA sequencing data with the different miRNAs in study</li> <li>"BV2_fastq_nfcore" contains the results of processing the fasta sequences with nfcore rnaseq workflow</li> <li>"Proinf_analysis" contains the analysis of the external bulk RNA sequencing data with the different studies of proinflammatory microglial cells</li> <li>"Spatial_data_analysis" contains the raw data of the spatial sequencing, the assempbly of the spatial expression profiles starting from the DAPI images and the transcripts coordinates, the analysis performed on the data</li> <li>"Spatial_U_scRNA_analysis" contains the code that integrates the spatial sequencing with the scRNA sequencing, plus the code of the analysis</li> </ul>
The expression level of RcCKXs.
<p>The expression level of RcCKXs.</p>
RNA-seq gene expression profiles from female ER-positive HER2-normal breast cancer patients
<p>Diagnostic samples (<em>n</em> = 59) from female breast cancer patients with ER-positive and HER2-normal tumors selected for neoadjuvant chemotehrapy.<br> </p> <p><strong>Data contents</strong></p> <table> <tbody> <tr> <td>README.txt</td> <td>README file</td> </tr> <tr> <td>meta_mat.tsv</td> <td>Metadata table</td> </tr> <tr> <td>expr_mat_probes.tsv.gz</td> <td>Expression matrix with probeset identifiers</td> </tr> <tr> <td>expr_mat_genes.tsv.gz</td> <td>Expression count matrix with gene identifiers</td> </tr> </tbody> </table>
Annona squamosa Leaf Extract Inhibit Migration of Human Cervical Cancer Cells Through MMP-9 Expression
<p><strong>Table 1. Interpretation of suspected acetogenin compounds isolates</strong></p>
Matters of development and experience: Evaluation of dog and human emotional expressions by children and adults
<p>Numerical data of children's and adults' ratings of facial images.</p>
Quantitative Expression of Latent Disease Factors in Individuals Associated with Psychopathology Dimensions and Treatment Response
<p>This repository contains preprocessed resting-state fMRI data including two datasets of obsessive-compulsive disorder (OCD): patients in baseline and patients with capsulotomy. The baseline dataset consists 104 OCD patients and 82 healthy controls were anonymously enrolled from our Institutional database. Part of the data from this cohort has been published previously [1, 2]. In this baseline dataset, 27 refractory patients underwent ventral capsulotomy with complete postoperative MRI scanning and clinical assessment. Exclusion/inclusion criteria, surgical procedure, and detailed clinical information were described in previously published work [1]. Clinical assessment included Y-BOCS, HAM-A, and HAM-D (17-item version). The fMRI data were minimally preprocessed using Statistical Parametric Mapping; the preprocessing pipeline details were described in previous studies [1, 2].</p> <p>1. Yin D, Zhang C, Lv Q, Chen X, Zeljic K, Gong H, et al. Dissociable frontostriatal connectivity: mechanism and predictor of the clinical efficacy of capsulotomy in obsessive-compulsive disorder. Biol Psychiatry. 2018;84:926–36.</p> <p>2. Chen X, Wang Z, Lv Q, Lv Q, van Wingen G, Fridgeirsson EA, Denys D, Voon V, Wang Z. Common and differential connectivity profiles of deep brain stimulation and capsulotomy in refractory obsessive-compulsive disorder. Mol Psychiatry. 2022;27(2):1020-1030. </p>
Development of a new class of radiopharmaceuticals for diagnosis and therapy of CXCR4-expressing malignancies based on the endogenous CXCR4 antagonist EPI-X4
<p>The pathological overexpression of the C-X-C motif chemokine receptor 4 (CXCR4) in more than 23 human cancers designate CXCR4 as a “wide spectrum” molecular target in oncology. In nuclear medicine, radiolabeled molecules can specifically target such cell surface receptors and can be designed for blending diagnostic and therapeutic properties within the same molecule (radio-theranostics). Recently, the applicants have identified an endogenous antagonist of CXCR4, termed EPI-X 4. EPI-X4 is a 16-mer peptide derived from human serum albumin that specifically binds CXCR4 but no other G-protein coupled receptors, without causing receptor activation. Several synthetic derivatives of EPI-X4 with increased affinity for CXCR4, resistance against proteolytic degradation in blood and high systemic retention times have been developed. Radiotheranostics based on EPI-X4 may thus offer new imaging tests and therapeutic options to patients suffering from CXCR4-expressing malignancies. The proposed research project would be the first study aiming to evaluate a new class of radiopharmaceuticals based on an endogenous peptide naturally present in the human body, which may have less off-target effects as compared to small molecules.</p>
Compendium of primary head and neck cancer gene expression datasets with accompanying clinical data
<p>We assembled a compendium of 30 primary HNC gene expression datasets with accompanying clinical data, representing the largest such resource for HNC. This resource was specifically built to identify genes associated with two outcome variables: patient survival and lymph node metastasis (LNM) status. Meta-analyses were applied to uniformly preprocessed gene expression data, as in our PRECOG resource (Gentles et al, Nat Med, 2016). Briefly, datasets were quality controlled, normalized, log transformed, and standardized to calculate gene expression profiles. Clinical data were manually curated and included survival and LNM status as well as variables relevant to HNC prognosis, such as tumor grade, tumor subanatomic location, and HPV status. The resulting 30 cleaned studies included 2,134 HNC tumors. 1,666 patients (across 17 cohorts) had survival outcome data and 1,490 patients (21 cohorts) had LNM status. Fully processed datasets are provided here as a resource to enable efficient meta-analyses of gene expression data in head and neck cancer.</p>
Fig. 7 in Identification of iron-chelating phenolics contributing to seed coat coloration in soybeans (Glycine max (L.) Merr.) expressing aryloxyalkanoate dioxygenase-12
Fig. 7. Absorbance spectra of genistin-iron complexes at pH 7 and pH 4.5.
Fig. 1 in Identification of iron-chelating phenolics contributing to seed coat coloration in soybeans (Glycine max (L.) Merr.) expressing aryloxyalkanoate dioxygenase-12
Fig. 1. Non-transgenic (A) and DAS-444Ø6-6 (B) whole soybean seeds.
Fig. 6 in Transcriptome sequencing of the apricot (Prunus armeniaca L.) and identification of differentially expressed genes involved in drought stress
Fig. 6. Relative expression of con (control) and tre (treat) genes by qRT-PCR (A) and RNA-Seq (B).
Fig. 2 in Transcriptome sequencing of the apricot (Prunus armeniaca L.) and identification of differentially expressed genes involved in drought stress
Fig. 2. Comparison of expression of differential unigenes identified between Treat and Control.
Inhibition of the α4β1 integrin activity by small Tellurium molecules Regulates PD-L1 Expression and Enhances Anti-Tumor Effect
<p>Figs source data</p>
Small Toy Liver TPM Expression Dataset
<p>Small TPM expression of genes in the liver. Original data is from GTEX V8 on TPM counts of genes in the liver.</p>
Small Toy Pancreas TPM Expression Dataset
<p>Small TPM expression of genes in the pancreas. Original data is from GTEX v8 on TPM counts of genes in the pancreas</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.