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6,234 results for “phenotypes”
Phenotypic resistance to pyrethroid associated to metabolic mechanism in Vgsc-L995F resistant-Anopheles gambiae malaria mosquitoes
<p>Pyrethroid resistance selection was performed over 20 generations with <em>Vgsc</em>-L995F <em>Anopheles gambiae</em> Tiassalé strain. <em>Vgsc</em>-L99F-resistant <em>An. gambiae</em> larvae were exposed to a sublethal dose (killing 20% of larvae) of deltamethrin (LS) and adults to PermaNet 2.0 (AS) at a sublethal time (killing 20% of adults) and combining exposure were realized at larvae and adult stages (LAS) and compared to unexposed group (NS). World Health Organization susceptible tube test was performed at each five generation to follow the evolutionary resistance to deltamethrin. The frequency of <em>Vgsc</em>-L995F/S mutation was screened using multiplex TaqMan qPCR method. Then, expression levels of detoxification enzymes associated to pyrethroid resistance, including CYP4G16, CYP6M2, CYP6P1, CYP6P3, CYP6P4, CYP6Z1 and CYP9K1, and glutathione S-transferase GSTe2 were measured.</p>
Quantifying Cell-State Densities in Single-Cell Phenotypic Landscapes using Mellon
<p>Processed data use in the the Mellon manuscript</p> <p>The following scanpy anndata objects are also available</p> <ol> <li>preprocessed_t-cell-depleted-bm-rna.h5ad: Anndata object for the RNA modality of the T-cell depleted bone marrow multiome dataset with normalized data, cell type annotations, clusters, pseudo time, fate propensities, MAGIC imputed expression data, cell-state densities, B-cell primed and lineage accessibility scores.</li> <li>preprocessed_t-cell-depleted-bm-atac.h5ad: Anndata object for the RNA modality of the T-cell depleted bone marrow multiome dataset with normalized data, cell type annotations, clusters, cell-state densities, B-cell primed and lineage peaks.</li> <li>preprocessed_t-cell-depleted-bm-rna-metacells.h5ad: Anndata object with metacells for the RNA modality of the T-cell depleted bone marrow multiome dataset .</li> <li>preprocessed_mouse-gastrulation-atlas.h5ad: Anndata object of the preprocessed mouse gastrulation data with normalized data, cell type annotations, clusters, pseudo time, fate propensities, MAGIC imputed expression data,</li> </ol>
Supplementary material 1 from: Jablonski D, Tzoras E, Panagiotopoulos A, Asztalos M, Fritz U (2023) Genotyping the phenotypic diversity in Aegean Natrix natrix moreotica (Bedriaga, 1882) (Reptilia, Serpentes, Natricidae). ZooKeys 1169: 87-94. https://doi.org/10.3897/zookeys.1169.104594
Supplementary information
Fig. 4 in Comprehensive evaluation of Bletilla striata and its substitutes by combining phenotypic characteristic, chemical composition, and anti-melanogenic activity
Fig. 4. Results of HCA (A) and PLS-DA analysis (B) for 27 batches of Bletillae Rhizoma.
Fig. 6 in Comprehensive evaluation of Bletilla striata and its substitutes by combining phenotypic characteristic, chemical composition, and anti-melanogenic activity
Fig. 6. The variable importance in the projection (VIP) of peak.
Fig. 5 in Comprehensive evaluation of Bletilla striata and its substitutes by combining phenotypic characteristic, chemical composition, and anti-melanogenic activity
Fig. 5. PLS-DA Loading scores plot of three different species of Bletillae Rhizoma.
Fig. 1 in Comparing essential oils from Australia's 'Victorian Christmas Bush' (Prostanthera lasianthos Labill., Lamiaceae) to closely allied new species: Phenotypic plasticity and taxonomic variability
Fig. 1. Prostanthera sp. Point Lookout displaying tell-tale leaf spots caused by fungal damage.
Behavioral and genetic architecture of fear conditioning and related phenotypes
<p>Analysis info and data files accompanying manuscript. Read info file first ("Zeid et al 2022 READ FIRST analysis info and syntax") for instructions on navigating the repository files. This repository includes each dataset as an SPSS file (.sav) and as an Excel file (.xlsx) with the same name.</p>
Thermal challenges reveal low phenotypic plasticity in common shallow water fish
<p>Climate variations in recent decades have led to an increase in ocean temperatures and an escalation in the number, intensity, and duration of marine heatwaves. Species such as <em>Pomatoschistus microps</em>, which inhabit shallow marine environments, are particularly exposed to these environmental extremes. This makes them ideal model species for assessing the impacts of ocean warming in these areas.</p> <p>Thermal tolerance, metabolic rate, and cellular stress response of this species were assessed after exposure to both present-day and projected future summer scenarios, along with their respective heatwaves.</p> <p>The thermal maximum did not appear to vary among the different scenarios tested, suggesting a limited acclimation capacity. Additionally, their metabolic rate remained stable, and there were no significant alterations in the levels of cellular stress response biomarkers. This lack of change suggests that their homeostatic state was not disrupted.</p> <p>Temperature data collected at the sampling site indicates that this species maintains a substantial thermal safety margin, which equips it to withstand thermal challenges not only in the present but also in anticipated future summer and heatwave conditions.</p>
Body composition phenotypes in older adults with COPD
Open the record for dataset details and reuse information.
Unveiling the Digital Phenotype of PA Behavior
ClinicalTrials.gov study NCT06094374. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
Impact of Comorbidities, Some Biomarkers, Micro RNA in Childhood Asthma Phenotypes
ClinicalTrials.gov study NCT07230912. IPD Sharing: NO. Countries: 0. Publications: 5.
Reducing Adolescent Suicide Risk: Safety, Efficacy, and Connectome Phenotypes of Intravenous Ketamine
ClinicalTrials.gov study NCT04613453. IPD Sharing: YES. Countries: 1. Publications: 0.
Young Stroke Service Deep Phenotyping: Exploring Recovery in Young Adult Survivors of Stroke
ClinicalTrials.gov study NCT07019493. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
A Comparison of Dendritic Cell Content and T-Cell Phenotype Between Granulocyte Colony-Stimulating Factor (G-CSF) or G-CSF + Granulocyte Macrophage (GM)-CSF
ClinicalTrials.gov study NCT00208949. IPD Sharing: Not stated. Countries: 1. Publications: 0.
INREAL - Nintedanib for Changes in Dyspnea and Cough in Patients Suffering From Chronic Fibrosing Interstitial Lung Disease (ILD) With a Progressive Phenotype in Everyday Clinical Practice: a Real-wor
ClinicalTrials.gov study NCT04702893. IPD Sharing: YES. Countries: 1. Publications: 0.
Investigating the Effect of Short-term Fasting on T Cell Metabolism, Function, and Phenotype in Obesity
ClinicalTrials.gov study NCT05886738. IPD Sharing: Not stated. Countries: 0. Publications: 2.
Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)
ClinicalTrials.gov study NCT07386015. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Metabolic Phenotyping During Stress Hyperglycemia in Cardiac Surgery Patients
ClinicalTrials.gov study NCT03743025. IPD Sharing: NO. Countries: 1. Publications: 0.
Biofiller and Gingival Phenotype Thickening
ClinicalTrials.gov study NCT07104019. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.