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Dataset results
5,225 results for “moderation”
A strategy for challenging tumorous bone regeneration by utilizing borosilicate bioactive glass synchronously boosting osteosarcoma combating and osteogenesis promotion of moderate magnetic hypertherm
GEO Series GSE294487. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome-wide analysis of the response of the thecosome pteropod Clio pyramidata to short-term moderate CO2 exposure
GEO Series GSE53151. Clio pyramidata. 8 samples. Type: Expression profiling by high throughput sequencing.
Safety and Efficacy of Atuzabrutinib Topical Gel in Patients with Mild-to-Moderate Atopic Dermatitis: Findings from Phase 2a Trial
GEO Series GSE289784. Homo sapiens. 39 samples. Type: Expression profiling by high throughput sequencing.
Gene-expression differences in peripheral blood between lithium responders and non-responders in the “Lithium Treatment -Moderate dose Use Study” (LiTMUS)
GEO Series GSE45484. Homo sapiens. 120 samples. Type: Expression profiling by array.
Comparative transcriptional analysis on cardiac ventricles between cryoinjury and moderate physical exercise in zebrafish
GEO Series GSE161641. Danio rerio. 2 samples. Type: Expression profiling by array.
Genome-wide DNA methylation analysis of peripheral blood samples of moderate-to-severe psoriasis patients treated with anti-TNF drugs
GEO Series GSE151278. Homo sapiens. 70 samples. Type: Methylation profiling by array.
Validation data: Multi-objective support vector regression reduces systematic error in moderate resolution maps of tree species abundance
<p>Validation data used in the analysis presented by Legaard et al. (in review). Validation data are sufficient to replicate model comparisons presented in this paper. Note that model training data were provided by the USDA Forest Service, Forest Inventory and Analysis Program through a collaborative agreement, are maintained by the USDA Forest Service as confidential, and cannot be shared.</p> <p>Legaard, K., Simons-Legaard, E., Weiskittel, A., Multi-objective support vector regression reduces systematic error in moderate resolution maps of tree species abundance, Remote Sensing, in review.</p>
Data from: Prophylactic digoxin treatment reduces IL-17 production in vivo in the neonatal calf and moderates RSV-associated disease
Respiratory syncytial virus (RSV) is a leading cause of morbidity and mortality in human infants. Bovine RSV infection of neonatal calves is pathologically and immunologically similar to RSV infection in infants, and is therefore a useful preclinical model for testing novel therapeutics. Treatment of severe RSV bronchiolitis relies on supportive care and may include use of bronchodilators and inhaled or systemic corticosteroids. Interleukin-17A (IL-17) is an inflammatory cytokine that plays an important role in neutrophil recruitment and activation. IL-17 is increased in children and rodents with severe RSV infection; and in calves with severe BRSV infection. It is currently unclear if IL-17 and Th17 immunity is beneficial or detrimental to the host during RSV infection. Digoxin was recently identified to selectively inhibit IL-17 production by antagonizing its transcription factor, retinoid-related orphan receptor γ t (RORγt). Digoxin inhibits RORγt binding to IL-17 and Th17 associated genes, and suppresses IL-17 production in vitro in human and murine leukocytes and in vivo in rodent models of autoimmune disease. We demonstrate here that in vitro and in vivo digoxin treatment also inhibits IL-17 production by bovine leukocytes. To determine the role of IL-17 in primary RSV infection, calves were treated prophylactically with digoxin and infected with BRSV. Digoxin treated calves demonstrated reduced signs of clinical illness after BRSV infection, and reduced lung pathology compared to untreated control calves. Digoxin treatment did not adversely affect virus shedding or lung viral burden, but had a significant impact on pulmonary inflammatory cytokine expression on day 10 post infection. Together, our results suggest that exacerbated expression of IL-17 has a negative impact on RSV disease, and that development of specific therapies targeting Th17 immunity may be a promising strategy to improve disease outcome during severe RSV infection.
Shallow and deep groundwater moderate methane dynamics in a high Arctic glacial catchment
<p>Geochemistry data of water samples taken of groundwater and river water in a glacial catchment on Svalbard during the summers of 2021 and 2022. </p>
Purity, Politics, and Polarization: Political Ideology Moderates Shifts in Moral Purity Beliefs to Economic Threat
<p>Study 1 Variables:</p> <p>Threat: Var00001 (1=threat, 2=control)</p> <p>Anxiety manipulation check: Anxiety</p> <p>Moral Foundations Endorsement: MFQ_HARM_AVG, MFQ_FAIRNESS_AVG, MFQ_INGROUP_AVG, MFQ_AUTHORITY_AVG, MFQ_PURITY_AVG</p> <p>Political Ideology (higher scores mean the participant is more conservative): PolitID</p> <p>Pro-life New Zealand charity: Purity_donation_true</p> <p> </p> <p>Study 2 Variables: </p> <p>Threat: Condition (1=threat, 0=control)</p> <p>Anxiety manipulation check: Anxiety</p> <p>Purity Endorsement: MFQ_HARM_AVG, MFQ_FAIRNESS_AVG, MFQ_INGROUP_AVG, MFQ_AUTHORITY_AVG, MFQ_PURITY_AVG</p> <p>Political Ideology (higher scores mean the participant is more conservative): POLiD</p> <p>Casual sex disapproval: xCASUAL_SEX</p>
Extended Evaluation of PROCHYMAL® Adult Human Stem Cells for Treatment-Resistant Moderate-to-Severe Crohn's Disease
ClinicalTrials.gov study NCT00543374. IPD Sharing: Not stated. Countries: 2. Publications: 0.
The Effects of Music Listening on Anxiety and Agitation in People With Mild and Moderate Cognitive Impairment
ClinicalTrials.gov study NCT05858541. IPD Sharing: YES. Countries: 1. Publications: 0.
A Clinical Study of MK-8527 in Participants With Mild and Moderate Hepatic Impairment (MK-8527-015)
ClinicalTrials.gov study NCT07025551. IPD Sharing: YES. Countries: 1. Publications: 0.
Retrograde Versus Antegrade Perfusion in Low-Moderate Hypothermia for Aortic Arch Surgery
ClinicalTrials.gov study NCT06986967. IPD Sharing: YES. Countries: 1. Publications: 0.
Alternative Feeding Regimen on Recovery of Children Aged 6-59 Months With Moderate Acute Malnutrition in Bangladesh.
ClinicalTrials.gov study NCT06045104. IPD Sharing: NO. Countries: 1. Publications: 0.
Intra-Articular Autologous Bone Marrow Mesenchymal Stem Cells Transplantation to Treat Mild to Moderate Osteoarthritis
ClinicalTrials.gov study NCT01459640. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Non-Interventional Clinical Study to Evaluate Long-Term Safety and Effectiveness of HUMIRA (Adalimumab) in Pediatric Patients With Moderately to Severely Active Crohn's Disease (CD)
ClinicalTrials.gov study NCT02130362. IPD Sharing: UNDECIDED. Countries: 22. Publications: 0.
Comparison of the Efficacy of Clindamycin Phosphate 1% Gel Versus Once-daily Dapsone 5% Gel in the Treatment of Moderate Acne Vulgaris
ClinicalTrials.gov study NCT05926869. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Comparison of Duac® Gel And Differin® Gel in Mild to Moderate Acne Vulgaris
ClinicalTrials.gov study NCT00160394. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Evolution of Oxidative Stress in Coronary Patients With Moderate Sleep Apnea Syndrome After Treatment With Continuous Positive Airway Pressure
ClinicalTrials.gov study NCT02893865. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.