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721 results for “ABI”
Crown morphology in Norway spruce (Picea abies [Karst.] L.) as adaptation to mountainous environments is associated with single nucleotide polymorphisms (SNPs) in genes regulating seasonal growth rhythm
Trees growing at high altitude or latitude have to be adapted, amongst others, to the lower temperatures, a shorter vegetation period, heavier snow load and frost desiccation. Association between molecular genetic markers and climatic variables may provide evidence for the genetic control of climatic adaptation. With increasing genomic resources, several genes with importance to climatic adaptation are identified over a wide range of tree species. Commonly, circadian clock genes are linked to the adaptation to lower temperatures and especially to a shortened vegetation period, as they are regulating metabolic and phenological processes in the day-night shift and seasonal change. Potentially adaptive "candidate" genes associated with latitudinal and elevational gradients were identified in several Picea spp. Before molecular markers became available to study climatic adaptation, phenotypic traits measured in natural populations and/or common garden studies were used to search for their association with climate variables. In Norway spruce, the crown architecture is the most noticeable trait associated with altitude and the related environment. The mountainous narrow-crowned morphotype is characterised by superior resistance to snow breakage in regions with heavy snow fall. In total, the crown shape was assessed in 765 individual trees from mountainous regions in the Thuringian Forest, the Ore Mountains (Saxony) and Harz Mountains (Lower-Saxony/Saxony-Anhalt), and they were genotyped at 44 single nucleotide polymorphisms (SNPs) in 24 adaptive trait related candidate genes. Six SNPs in three genes, APETALA 2-like 3 (AP2L3), GIGANTEA (GI), and mitochondrial transcription termination factor (mTERF) were associated with variation in crown shape. GI has previously been identified in angiosperms and gymnosperms to be associated with temperature and growth cessation. Our results showed that crown morphology in Norway spruce is associated with genetic markers which are putatively involved in the complex process of genetic adaptation to climatic conditions at high altitudes.
Contrail altitude estimation using GOES-16 ABI data and deep learning: Dataset of contrails collocated with CALIOP satellite measurements
Open the record for dataset details and reuse information.
ABI sequencing files for mouse Prex2 mutant sequence verification
<p>File HWZD44_3A_1-P0058.ab1 is an ABI sanger sequencing trace showing the presece of the mutation E22A in exon 1 of mouse Prex2,</p> <p>File 59_2h-P0060.ab1 is an ABI sanger sequencing trace showing the presece of the mutation N204A in exon 6 of mouse Prex2.</p>
DNA sequences of transgenes detected via environmental DNA (raw ABI files, processed FASTA files, and reference alignments)
We demonstrate that simple, non-invasive environmental DNA (eDNA) methods can detect transgenes of genetically modified (GM) animals from terrestrial and aquatic sources in invertebrate and vertebrate systems. We detected transgenic fragments between 82-234 bp through targeted PCR amplification of environmental DNA extracted from food media of GM fruit flies (<i>Drosophila melanogaster</i>), feces, urine, and saliva of GM laboratory mice (<i>Mus musculus</i>), and aquarium water of GM tetra fish (<i>Gymnocorymbus ternetzi</i>). With rapidly growing accessibility of genome-editing technologies such as CRISPR, the prevalence and diversity of GM animals will increase dramatically. GM animals have already been released into the wild with more releases planned in the future. eDNA methods have the potential to address the critical need for sensitive, accurate, and cost-effective detection and monitoring of GM animals and their transgenes in nature.
Dataset to: The efficiency of retention measures in continuous-cover forestry for conserving epiphytic cryptogams: A case study on Abies alba
<p>The file contains data used in the paper mentioned aboved.</p> <p>Abbreviations of variables, species etc. please see Table 1 and Appendix S5 in the publication, respectively.</p> <p>The variables dbh and ele (elevation) are already transformed.</p> <p>The sheets "Ordination_Epiphytes_spec" and "Ordination_Epiphytes_env" were also used for detecting significant associations of species to the tree types (HT vs. AT).</p> <p> </p>
Microsatellite genotypes of Japanese abies species: Insights from population genetics and SDM
<p><span>Range shifts during the Pleistocene shaped the unique phylogeographical structures of many species. Pleistocene range shifts gave currently allopatric species opportunities to occur in sympatry, likely resulting in ancient introgressions between related taxa. In our study, we investigate the range shifts and introgression patterns of three Japanese <em>Abies </em>species (<em>A. firma, A. homolepis, and A. veitchii</em>) by employing an extensive survey of 43 populations. This survey includes comprehensive analysis of both mitochondrial (mtDNA) and nuclear (18 microsatellites) genomes, in combination with species distribution modeling (SDM). It is important to note that these two types of markers provide distinct and complementary information, as they have different modes of inheritance and mutation rates. Bayesian clustering analysis indicates that the three species were clearly separated, with the exception of the <em>A. homolepis </em>var. <em>umbellata</em> population, which is considered a natural hybrid between <em>A. homolepis</em> and <em>A. firma</em>. However, mtDNA haplotypes of the four northern populations of <em>A. firma</em> were entirely replaced by two major haplotypes of <em>A. homolepis </em>and <em>A. veitchii.</em> The results of Neighbor-net, NewHybrids, STRUCTURE analyses, and SDM suggest that historical introgression between species occurred in each geographic region, with mtDNA capture being the likely mechanism. However, contrary to these findings, the ABC coalescent analysis did not support an ancient introgression. Therefore, further validation with genome-wide level data is needed to clarify this issue. Our conclusion is that climate-induced range shifts during the Pleistocene/Holocene likely played a crucial role in the observed patterns of introgression in these species.</span></p>
Trial of Combination ABI-007, Carboplatin, and Gemcitabine for First Line Treatment of Advanced Urothelial Cancer
ClinicalTrials.gov study NCT00995488. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Phase 2 Study of Nab-sirolimus (ABI-009) in Patients With Advanced Malignant PEComa
ClinicalTrials.gov study NCT02494570. IPD Sharing: Not stated. Countries: 1. Publications: 3.
A Study Evaluating ABI-H0731+ Entecavir vs Entecavir Alone for the Treatment of Viremic HBeAg-positive Participants With Chronic Hepatitis B Virus Infection (cHBV)
ClinicalTrials.gov study NCT03577171. IPD Sharing: Not stated. Countries: 5. Publications: 1.
A Study of ABI-H0731 + Nucleos(t)Ide as Finite Treatment for Chronic Hepatitis B Patients
ClinicalTrials.gov study NCT03780543. IPD Sharing: NO. Countries: 5. Publications: 1.
Neo-adjuvant Gemcitabine, Epirubicin, ABI-007 (GEA) in Locally Advanced or Inflammatory Breast Cancer
ClinicalTrials.gov study NCT00193206. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Weekly vs. Every 2 Week vs. Every 3 Week Administration of ABI-007 (Abraxane)/Bevacizumab Combination in Metastatic Breast Cancer
ClinicalTrials.gov study NCT00281528. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Phase III Study of ABI-007(Albumin-bound Paclitaxel) Plus Gemcitabine Versus Gemcitabine in Metastatic Adenocarcinoma of the Pancreas
ClinicalTrials.gov study NCT00844649. IPD Sharing: Not stated. Countries: 11. Publications: 16.
ABI-007 (Nab-Paclitaxel) and Gemcitabine in Treating Women With Metastatic Breast Cancer
ClinicalTrials.gov study NCT00110084. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic Hepatitis B Infection
ClinicalTrials.gov study NCT03576066. IPD Sharing: UNDECIDED. Countries: 3. Publications: 1.
Auditory Brainstem Implant (ABI) in Adult Non-Neurofibromatosis Type 2 Subjects
ClinicalTrials.gov study NCT01736267. IPD Sharing: Not stated. Countries: 1. Publications: 4.
A Study Evaluating Treatment Regimens Containing Vebicorvir (ABI-H0731) in Participants With Chronic Hepatitis B Infection
ClinicalTrials.gov study NCT04820686. IPD Sharing: NO. Countries: 4. Publications: 1.
Albumin-bound Paclitaxel (ABI-007) for Patients With Advanced Non-Small Cell Lung Cancer
ClinicalTrials.gov study NCT00540514. IPD Sharing: Not stated. Countries: 2. Publications: 9.
Neoadjuvant ABI-007, Carboplatin and Gemcitabine in Locally Advanced Bladder Cancer
ClinicalTrials.gov study NCT00585689. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Preoperative Bevacizumab and Trastuzumab With ABI-007 and Carboplatin in HER2+ Breast Cancer
ClinicalTrials.gov study NCT00392392. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.