Find research datasets worth reusing

opencc-by-4.0Mar 2022View details →

Dataset: Multi-Stakeholder Validation of Entrustable Professional Activities for a Family Medicine Care of the Elderly Residency Program: A Focus Group Study

ZOOM Meeting transcripts from 5 stakeholder group meetings used in the study.

opencc-by-4.0Jun 2022View details →

Data supporting paper "Efficient numerical simulation of density-driven flows: Application to the 2- and 3-D Elder problem"

Data supporting paper "Efficient numerical simulation of density-driven flows: Application to the 2- and 3-D Elder problem", Water Resources Research.

opencc-by-4.0Jul 2022View details →

Data results of the usability study of PedaleoVR from PwLLD and elderly people

Data results of the usability study of a virtual reality application for cycling exercise in patients with lower limb disorders and elders. This dataset collection includes the results of the Intrinsic Motivation Inventory (IMI), the Credibility and Expectancy Questionnaire (CEQ) and the System Usability Scale (SUS) completed by patients with lower limb disorders (PwLLD). And it is also includes the results of the System Usability Scale (SUS), the Presence Questionnaire (PQ), the Game User Experience Satisfaction Scale (GUESS) of 18 items and the Sickness Simulator Questionnaire (SSQ) (pre-post exposure to the VR system) completed by elders.

opencc-by-4.0May 2022View details →

Effectiveness of COVID-19 vaccination on reduction of hospitalizations and deaths in elderly patients in Rio Grande do Norte, Brazil

Data Repository  Dataset name: covid19_rn-br.csv  Version: 1.0  Data collection period: 04/2020 - 08/2021  Dataset Characteristics: Multivalued  Number of Instances: 12,635 Number of Attributes: 16 Missing Values: Yes  Area(s): Health Sources:  - Primary:  <ul> <li>RegulaRN (<a href="https://regulacao.saude.rn.gov.br/sala-situacao/sala_publica/">https://regulacao.saude.rn.gov.br/sala-situacao/sala_publica/</a>).</li> </ul> - Secondary:  <ul> <li>RN Mais Vacina (<a href="https://rnmaisvacina.lais.ufrn.br/cidadao/">https://rnmaisvacina.lais.ufrn.br/cidadao/</a>).</li> </ul> Description: The covid19_rn-br.csv dataset is composed of data from individuals who were hospitalized due to the Sars-CoV-2 virus. The data comes from the ecosystem of services that includes the regulatory system for clinical and critical beds related to Covid-19 (RegulaRN) and the vaccination system against Covid-19 that records the data of the general population (RN Mais Vacina) from Rio Grande do Norte state, Brazil. This dataset provides elementary data to analyze the impact of vaccination on patients hospitalized in the state. Table 1 presents the dictionary used during the data analysis.   Table 1: Description of Dataset Features.  <table> <tbody> <tr> <td> Attributes  </td> <td> Description  </td> <td> datatype  </td> <td> Value </td> </tr> <tr> <td> usp </td> <td> Unified Score for Prioritization scale, which combines the parameters described in the quick Sequential Organ Failure Assessment (qSOFA), the Charlson Comorbidity Index (CCI), the Clinical Frailty Scale (CFS) and The Karnofsky Performance Status scores </td> <td> Numerical </td> <td> 2.0. 3.0, 4.0, 5.0, 6.0+ </td> </tr> <tr> <td> age </td> <td> Informs the patient's age </td> <td> Numerical. </td> <td> integer value for age </td> </tr> <tr> <td> outcome </td> <td> Informs the outcome of the hospitalized patient after leaving the hospital </td> <td> Categorical </td> <td> “Discharge” or “Death" </td> </tr> <tr> <td> comorbidities </td> <td> Informs if the patient has comorbidities </td> <td> Categorical. </td> <td> “Yes” or “No” </td> </tr> <tr> <td> vaccine </td> <td> Informs which type of vaccine was applied to the patient </td> <td> Categorical </td> <td> “Vaccine #1”, “Vaccine #2” or NaN </td> </tr> <tr> <td> bed_date_admission  </td> <td> Informs the date the patient was hospitalized </td> <td> Date </td> <td> Date </td> </tr> <tr> <td> bed_date_outcome </td> <td> Informs the date that the patient left the hospital bed </td> <td> Date </td> <td> Date </td> </tr> <tr> <td> length_hospitalization </td> <td> Informs the number of days that the patient was hospitalized </td> <td> Numerical </td> <td> An integer value for days </td> </tr> <tr> <td> interval_d1_hospitalization </td> <td> Informs the interval (in days) that the patient had between the first dose and admission </td> <td> Numerical </td> <td> An integer value for days or NaN </td> </tr> <tr> <td> interval_d2_hospitalization </td> <td> Informs the interval (in days) that the patient had between the second dose and admission </td> <td> Numerical </td> <td> An integer value for days or NaN </td> </tr> <tr> <td> dt_d1 </td> <td> Informs the date of application of the patient's first dose </td> <td> Date </td> <td> Date or NaN </td> </tr> <tr> <td> dt_d2 </td> <td> Informs the patient's second dose application date </td> <td> Date </td> <td> Date or NaN </td> </tr> <tr> <td> comorbidities_txt </td> <td> Informs patients' comorbidities </td> <td> Categorical </td> <td> Free text or NaN </td> </tr> <tr> <td> immunization </td> <td> It informs the patient's immunization level according to the number of doses received and the interval (in days) of application of these doses </td> <td> Categorical </td> <td> “Partially”, “Fully” or “Not vaccinated” </td> </tr> <tr> <td> health_professionals </td> <td> Informs if the patient is a health professional </td> <td> Boolean </td> <td> 0 or 1 </td> </tr> <tr> <td> age_group </td> <td> Informs the age group of the hospitalized patient according to their age </td> <td> Categorical </td> <td> 0-19, 20-49, 50-59, 60-69, 70-79, 80-89, 90+ </td> </tr> </tbody> </table>   Article: Effectiveness of COVID-19 vaccination on reduction of hospitalizations and deaths in elderly patients in Rio Grande do Norte, Brazil Authors: Ana Isabela L. Sales-Moioli, Leonardo J. Galvão-Lima, Talita K. B. Pinto, Pablo H. Cardoso, Rodrigo D. Silva, Felipe Fernandes, Ingridy M. P. Barbalho, Fernando L. O. Farias, Nicolas V. R. Veras, Gustavo F. Souza, Agnaldo S. Cruz, Ion G. M. Andrade, Lúcio Gama, Ricardo A. M. Valentim

opencc-by-4.0Apr 2024View details →

Exploring the Interaction Between Proprioceptive Sensitivity in the Hip, Knee, and Ankle Joints, Alongside Stability Limits Evaluated Through Computerized Posturography, in Elderly Individuals Afflicted with Fibromyalgia Syndrome.

Objectives: This study investigates proprioceptive sensitivity and stability limits in patients with Fibromyalgia syndrome (FMS) compared to healthy controls, focusing on joint reposition sense (JRS) and limits of stability (LOS). By delineating differences between the groups, it aims to uncover the proprioceptive deficits that contribute to balance impairments in FM sufferers. Additionally, the study explores correlations between JRS and LOS within the FM group, potentially informing targeted therapeutic strategies to enhance patient outcomes.   Methods: Fifty-four individuals with FM and 54 healthy controls participated in this research. Using precise digital inclinometers, JRS was evaluated at the hip, knee, and ankle joints. LOS was assessed using dynamic posturography with advanced iso-free technology. Various parameters were measured, including reaction time, maximum excursion, and directional control.   Results: Individuals with FM exhibited significant differences in JRS and LOS compared to healthy controls. For JRS errors in the hip, knee, and ankle joints (mean ± SD), the FM group showed 3.2° ± 0.6°, 2.9° ± 0.5°, and 3.5° ± 0.7°, respectively, while the control group exhibited 1.1° ± 0.4°, 1.0° ± 0.3°, and 1.2° ± 0.4°, respectively. In LOS, FM individuals had a reaction time of 1.8 ± 0.3 seconds, maximum excursion of 54.6% ± 6.2%, and directional control of 65.2% ± 5.8%, while healthy controls showed 0.9 ± 0.2 seconds, 72.4% ± 7.1%, and 77.8% ± 6.9%, respectively.   Conclusions: Correlation analysis revealed significant associations between JRS parameters and LOS outcomes within the FMS group, indicating that better proprioception was linked to improved postural stability. These findings have clinical implications for assessing and managing balance impairments in individuals with FMS, potentially contributing to the development of targeted interventions to improve their quality of life.

opencc-by-4.0May 2024View details →

Biomechanical Analysis of Limits of Stability Using Computerized Posturography: Correlations with Functional Mobility in Elderly Individuals with Hip Osteoarthritis – A Cross-Sectional Study

The study titled "Biomechanical Analysis of Limits of Stability Using Computerized Posturography: Correlations with Functional Mobility in Elderly Individuals with Hip Osteoarthritis – A Cross-Sectional Study" delves into the intricate relationship between postural stability and functional mobility in elderly patients suffering from hip osteoarthritis (OA). Utilizing advanced computerized posturography, the research quantitatively assesses the limits of stability (LOS) in various directional planes, providing a comprehensive biomechanical profile of the participants. The findings reveal significant discrepancies in LOS between hip OA patients and age-matched asymptomatic controls, underscoring the profound impact of hip OA on balance and stability. Additionally, the study examines the correlation between LOS measurements and functional mobility, as assessed by the Timed Up and Go (TUG) test. The results indicate a strong association, suggesting that diminished postural stability in hip OA patients contributes to impaired functional mobility. This cross-sectional analysis highlights the importance of targeted interventions to enhance stability and mobility in this population, aiming to mitigate the risk of falls and improve overall quality of life.

opencc-by-4.0Mar 2018View details →

Detail on the Bruegel the Elder print NHD49

Detail on the Bruegel the Elder print NHD49

opencc-by-4.0Sep 2024View details →

FLUOROQUINOLONE NEUROTOXICITY IN THE ELDERLY

Older patients are taking more and more antibiotics, including fluoroquinolones. Their toxic effects on the nervous system and the psyche are well known but not well described and explained. We sought to determine the number and severity of adverse effects on the nervous system and psyche caused by fluoroquinolones in patients over 65 years of age. We analyzed fluoroquinolone reports submitted to the Canada Vigilance Adverse Reaction Online Database and the Australian Database of Adverse Event Notification. A systematic literature search was also conducted. Confusion and hallucinations were the predominant symptoms caused primarily by ciprofloxacin. The review of the publications indicates an increased incidence of adverse effects on the nervous system in the elderly. Treatment with fluoroquinolones in the elderly should be closely monitored due to the potential for neurotoxicity manifesting as neurological and/or psychiatric symptoms and the risk of misdiagnosis.

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Data from: The genetic landscape of axonal neuropathies in the middle aged and elderly: focus on MME (supplementary information)

OBJECTIVE: To test the hypothesis that monogenic neuropathies such as Charcot-Marie-Tooth disease (CMT) contribute to frequent but often unexplained neuropathies in the elderly, we performed genetic analysis of 230 patients with unexplained axonal neuropathies and disease onset >35 years. METHODS: We recruited patients, collected clinical data and conducted whole-exome sequencing (WES, n=126) and MME single-gene sequencing (n=104). We further queried WES repositories for MME variants and measured blood levels of the MME-encoded protein neprilysin. RESULTS: In the WES cohort, the overall detection rate for assumed disease-causing variants in genes for CMT or other conditions associated with neuropathies was 18.3% (familial cases 26.4%, apparently sporadic cases 12.3%). MME was most frequently involved and accounted for 34.8% of genetically solved cases. The relevance of MME for late-onset neuropathies was further supported by detection of a comparable proportion of cases in an independent patient sample, preponderance of MME variants among patients compared to population frequencies, retrieval of additional late-onset neuropathy patients with MME variants from WES repositories, and low neprilysin levels in patients' blood samples. Transmission of MME variants was often consistent with an incompletely penetrant autosomal dominant trait and less frequently with autosomal recessive inheritance. CONCLUSIONS: A detectable fraction of unexplained late-onset axonal neuropathies is genetically determined, either by variants in CMT genes or genes involved in other conditions that affect the peripheral nerves and can mimic a CMT phenotype. MME variants can act as completely penetrant recessive alleles but also confer dominantly inherited susceptibility to axonal neuropathies in an aging population.

opencc-zeroAug 2021View details →

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The elephant in the family: Costs and benefits of elder siblings on younger offspring life-history trajectory in a matrilineal mammal

1. Many mammals grow up with siblings, and interactions between them can influence offspring phenotype and fitness. Among these interactions, sibling competition between different-age offspring should lead to reproductive and survival costs on the younger sibling, while sibling cooperation should improve younger sibling's reproductive potential and survival. However, little is known about the consequences of sibling effects on younger offspring life history trajectory, especially in long-lived mammals. 2. We take advantage of a large, multigenerational demographic dataset from semi-captive Asian elephants to investigate how the presence and sex of elder siblings influence the sex, survival until five years old, body condition, reproductive success (i.e. age at first reproduction and lifetime reproductive success), and long-term survival of subsequent offspring. 3. We find that elder siblings have heterogenous effects on subsequent offspring life-history traits depending on their presence, their sex, and the sex of the subsequent offspring (named focal calf). 4. Overall, the presence of an elder sibling (either sex) strongly increased focal calf long-term survival (either sex) compared to sibling absence. However, elder sisters had higher impact on the focal sibling than elder brothers. Focal females born after a female display higher long-term survival, and decreased age at first reproduction when raised together with an elder sister rather than a brother. Focal males born after a female rather than a male showed lower survival but higher body weight when both were raised together. We did not detect any sibling effects on the sex of the focal calf sex, survival until five years old and lifetime reproductive success. 5. Our results highlight the general complexity of sibling effects, but broadly that elder siblings can influence the life-history trajectory of subsequent offspring. We also stress the importance of considering all life stages when evaluating sibling effects on life trajectories. 22-Jul-2021 --

opencc-zeroAug 2021View details →

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Prehabilitation program in elderly patients: a prospective cohort study

The preoperative period may be an opportune period to optimize the patients' physical condition with a multimodal preoperative program. The impact of a "prehabilitation" program in elderly patients is discussed. This mono-centre observational cohort study included consecutively 139 patients planned for major abdominal and thoracic surgery: 44 in the control group (age<65) and 95 in the elderly group (age> 65). All patients followed a "prehabilitation" program including exercise training, nutritional optimization, psychological support, and behavior change. Seventeen patients in the control group and 45 in the elderly group completed the study at six months. The 6-minute walk test (6MWT) increased in both groups from the initial evaluation to the last one (median value of 80 m [interquartile range 51] for those under 65 years; 59 m [34] for the older ones; P=0.114). The 6MWT was also similar after one month of prehabilitation for both populations. The rate of postoperative complications was similar in the two groups. Prehabilitation showed equivalence in patients over 65 years of age compared to younger patients in terms of increase in functional capabilities and of postoperative evolution. This multimodal program represents a bundle of care which can benefit the frailer population.

opencc-zeroSep 2021View details →

opencc-by-nc-1.0Jan 2019View details →

Statue of Isabella Elder (v2)

Isabella Elder (1828-1905) was one of Scotland's greatest female philanthropists. She was renowned for her work to improve the lives of Govan's residents and for her interest in education, particularly in widening education opportunities for women. http://portal.historicenvironment.scot/designation/LB33304 This model generated using AgiSoft MetaShape using the new DepthMap workflow (generate mesh from sparse point cloud using Image DepthMaps rather than from dense point cloud) from a set of 30 photographs. All processing on default parameters, with additional background and scenery removed before upload. The 'lump' on top of the statue seen here was also generated when Meshroom was used (see https://sketchfab.com/models/dbb15476fed44306ad50be227b2587f2), but was manually removed in the version of the model uploaded from Meshroom. Source: Objaverse 1.0 / Sketchfab

A Comparison of the I-gel and Self-pressurised Air-Q Intubating Laryngeal Airway (Air-Q sp) in the Elderly Patients

ClinicalTrials.gov study NCT02260427. IPD Sharing: Not stated. Countries: 1. Publications: 1.

Effect of Passive Exercise on Systemic Endothelial Function in Elderly Patients With Chronic Heart Failure

ClinicalTrials.gov study NCT00733161. IPD Sharing: Not stated. Countries: 1. Publications: 1.

Three Care Models for Elderly Patients With Hip Fracture

ClinicalTrials.gov study NCT01350557. IPD Sharing: NO. Countries: 1. Publications: 3.

Geriatric Assessment Directed Trial to Evaluate Gemcitabine +/- Nab-paclitaxel in Elderly Pancreatic Cancer Patients

ClinicalTrials.gov study NCT02812992. IPD Sharing: NO. Countries: 1. Publications: 1.

The Effects of PFMT and MPE in Elderly Women With SUI.

ClinicalTrials.gov study NCT05390008. IPD Sharing: NO. Countries: 1. Publications: 5.

Milk Biofortification Promotes Health Benefits in Institutionalized Elderly

ClinicalTrials.gov study NCT02980094. IPD Sharing: NO. Countries: 1. Publications: 5.

Diffrence in Thromboprofilaksis in Elderly Ostoepenic Hip Fractures According to Mobility Status by Genetic Analysis

ClinicalTrials.gov study NCT06959017. IPD Sharing: Not stated. Countries: 1. Publications: 1.

Safety of Ramelteon in Elderly Subjects

ClinicalTrials.gov study NCT00568789. IPD Sharing: Not stated. Countries: 1. Publications: 2.