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4,230 results for “Energie”

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zenodo44/100

UFLUX 100m half-yearly carbon, water, and energy fluxes in Europe in 2018

<div> <h3>UFLUX Ensemble Europe100m6monthly (European 100 6-monthly) in 2018</h3> <p><strong>Overview</strong><br>The&nbsp;<strong>UFLUX ensemble dataset</strong>&nbsp;offers&nbsp;<strong>European fluxes at 100 m spatial resolution</strong>, generated using&nbsp;<strong>Deep Forest machine learning models</strong>. It integrates&nbsp;<strong>satellite-based Sentinel-2 vegetation proxies NIRv</strong>&nbsp;with&nbsp;<strong>ERA5 climate reanalysis</strong>, and is trained against&nbsp;<strong>ICOS eddy covariance observations</strong>. The UFLUX project includes five core flux components:</p> <ul> <li> <p>Gross Primary Production (<strong>GPP</strong>)</p> </li> <li> <p>Ecosystem Respiration (<strong>RECO</strong>)</p> </li> <li> <p>Net Ecosystem Exchange (<strong>NEE</strong>)</p> </li> <li> <p>Sensible Heat Flux (<strong>H</strong>)</p> </li> <li> <p>Latent Energy Flux (<strong>LE</strong>)</p> </li> </ul> <p><strong>Background and Methodology</strong><br>The&nbsp;<strong>Unified FLUXes (UFLUX)</strong>&nbsp;initiative is a data-driven, machine learning-based platform designed to upscale eddy covariance (EC) flux measurements from tower sites to the global scale. It aims to answer pressing questions about how effectively terrestrial ecosystems are managed under climate change.</p> <p>Key innovations of UFLUX include:</p> <ol> <li> <p><strong>Consistent Upscaling Framework</strong>: Harmonizes flux upscaling across spatial/temporal scales and multiple flux types (GPP, RECO, etc.) using deep decision tree-based methods, better suited than conventional neural networks for EC flux data.</p> </li> <li> <p><strong>Hybrid Explainable ML</strong>: Combines black-box ML with ecological interpretability through residual learning, offering both predictive power and new scientific insight (UFLUXv2).</p> </li> <li> <p><strong>Uncertainty Quantification</strong>: Employs sampling space completeness to assess model uncertainty in a transparent, robust manner.</p> </li> <li> <p><strong>Multisource Integration</strong>: Leverages complementary strengths of vegetation proxies (e.g., NIRv, SIF) and climate data (e.g., ERA5) to represent carbon dynamics more comprehensively than single-source approaches.</p> </li> <li> <p><strong>Superior Gap-Filling</strong>: Originally developed as a global EC flux gap-filling tool, UFLUX improves accuracy by up to 30% and reduces uncertainty by as much as 70% compared to traditional methods.</p> </li> <li> <p><strong>High Performance</strong>: Achieves strong predictive accuracy, with global-scale R&sup2; &gt; 0.8 for RECO and &asymp;0.9 for GPP, while being computationally efficient enough to run on a standard laptop.</p> </li> <li> <p><strong>Community Adoption</strong>: Already used by other global upscaling projects, highlighting its reliability and impact.</p> </li> </ol> <p><strong>Applications</strong><br>UFLUX is ideal for studying the interactions between land management, climate change, and carbon fluxes, particularly in improving global estimates of GPP and RECO by addressing biases in EC measurements.</p> <p><strong>Resources</strong></p> <ul> <li><strong>UFLUX Website:&nbsp;<a href="https://github.com/soonyenju/uflux" target="_new" rel="noopener">https://sites.google.com/view/uflux</a></strong></li> <li> <p><strong>Code Repository</strong>:&nbsp;<a href="https://github.com/soonyenju/uflux" target="_new" rel="noopener">https://github.com/soonyenju/uflux</a></p> </li> <li> <p><strong>Technical &amp; Descriptive Publication</strong>:&nbsp;<a href="https://doi.org/10.1080/01431161.2024.2312266" target="_new" rel="noopener">https://doi.org/10.1080/01431161.2024.2312266</a></p> </li> </ul> </div>

opencc-by-4.0Aug 2023View details →
zenodo44/100

SPEChpc 2021 Benchmarks: A Performance and Energy Case Study

SPEChpc 2021 Benchmarks on Ice Lake and Sapphire Rapids based Infiniband Clusters: A Performance and Energy Case Study.

opengpl-2.0Aug 2023View details →
zenodo44/100

High Energy Lightning Emission Network (HELEN) Flight 7a 06/19/2023

<p>Data gathered during the flight of the&nbsp;High Energy Lightning Emission Network (HELEN) on June 19th, 2023. The first file, 1-Flight7a-Raw Data.zip, is the raw data taken directly from the payloads&#39; micro SD cards. In the second file,&nbsp;2-Flight7a-Data to Process.zip, the data has been cleaned and is suitable for further processing. The third file,&nbsp;3-Flight7a-Processed Data.zip, contains data that has been combined and&nbsp;temporally synced. This data can be easily read into MATLAB and used to reproduce results.</p>

opencc-by-4.0Sep 2023View details →
zenodo44/100

THz driven field emission: energy and time-of-flight spectra of ions (DATASET)

<p>We present an experimental and numerical study of ion field evaporation from LaB6 nanotips using single-cycle terahertz (THz) transients and a static bias voltage. Varying the amplitude and phase of the THz pulses and the value of the<br> bias, we explore the THz-induced reshaping of the ions energy and their time-of-flight spectra. These results prove that short THz transient of about 1 ps can induce ionization and emission of ions from LaB6 samples by a field effect: the THz<br> transient acts as an ultra-short electrical pulse. Moreover, comparing numerical and experimental results, we prove that the response time of surface atoms to the THz&nbsp;transient is shorter than 1 ps, corresponding to the vibration times of acoustic phonons<br> in LaB6.</p> <p>In the following dataset, you can find data from THz-APT obtained from LaB6 sample and results of simulation of ions under THz Field done with Lorentz</p>

opencc-by-4.0Sep 2023View details →
zenodo44/100

Pion Energy Regression in High-Granularity Calorimeter Prototype

<p>The dataset consists of simulations of calibrated reconstructed hits produced by a pion passing through the HGCAL test beam prototype. For the simulations, Monte Carlo method is used to produce the pions with energy ranging from 10 to as high as 500 GeV. The dataset contains the coordinates of the calibrated reconstructed hits in the prototype along with the calibrated energy in units of MIP.&nbsp;The HDF5 files can be extracted from the gzip files.</p>

opencc-by-4.0Apr 2023View details →
zenodo44/100

Optimized stationary points on the potential energy surface of the reaction of atomic oxygen O(3P) with acrylonitrile

<p>This Zip file contains the cartesian coordinates of optimized stationary points of the&nbsp;O(<sup>3</sup>P) + acrylonitrile potential energy surface (PES).</p> <p>The&nbsp;PES has been published in our article&nbsp;&ldquo;A Computational Analysis of the Reaction of Atomic Oxygen O(<sup>3</sup>P) with Acrylonitrile&rdquo;</p> <p>(<em>Lecture Notes in Computer Science</em> <strong>2021</strong>,&nbsp;12958, 339-350), that can be found in&nbsp;https://doi.org/10.1007/978-3-030-87016-4_25 .</p> <p>All calculations have been performed with&nbsp; Gaussian 09, Revision D.01.</p> <p>All structures have been optimized&nbsp;at B3LYP/aug-cc-pVTZ level of theory.</p>

opencc-by-4.0Oct 2023View details →
zenodo44/100

Optimized stationary points on the potential energy surfaces of the N(2D) + CH2CHCN and CN + CH2CHCN reactions

<p>This Zip file contains the cartesian coordinates of optimized stationary points on&nbsp;the potential energy surfaces (PESs) of two reactions: N(<sup>2</sup>D) + CH<sub>2</sub>CHCN (acrylonitrile) and CN +&nbsp;CH<sub>2</sub>CHCN.</p> <p>The&nbsp;PES has been published in our article&nbsp;&ldquo;A Theoretical Investigation of&nbsp;the&nbsp;Reactions of&nbsp;N(<sup>2</sup>D) and&nbsp;CN with&nbsp;Acrylonitrile and&nbsp;Implications for&nbsp;the&nbsp;Prebiotic Chemistry of&nbsp;Titan&rdquo;</p> <p>(<em>Lecture Notes in Computer Science</em> <strong>2022</strong>,&nbsp;13378, 246-259), that can be found in&nbsp;https://doi.org/10.1007/978-3-031-10562-3_18&nbsp;.</p> <p>All calculations have been performed with&nbsp; Gaussian 09, Revision D.01.</p> <p>All structures have been optimized&nbsp;at B3LYP/aug-cc-pVTZ level of theory.</p>

opencc-by-4.0Oct 2023View details →
zenodo44/100

Optimized stationary points on the potential energy surfaces of the N(2D)+ C2H4 and N(2D)+ CH2CHCN reactions

<p>This Zip file contains the cartesian coordinates of optimized stationary points on the potential energy surfaces&nbsp;(PESs) of two reactions: N(<sup>2</sup>D)+ C<sub>2</sub>H<sub>4</sub>&nbsp;and&nbsp;N(<sup>2</sup>D)+ CH<sub>2</sub>CHCN.</p> <p>The&nbsp;PESs have&nbsp;been published in our article&nbsp;&ldquo;Computational Investigation of&nbsp;the&nbsp;N(<sup>2</sup>D)+ C<sub>2</sub>H<sub>4</sub>&nbsp;and&nbsp;N(<sup>2</sup>D)+ CH<sub>2</sub>CHCN Reactions: Benchmark Analysis and&nbsp;Implications for&nbsp;Titan&rsquo;s Atmosphere&rdquo;</p> <p>(<em>Lecture Notes in Computer Science</em> <strong>2023</strong>,&nbsp;14105, 705-717), that can be found in&nbsp;https://doi.org/10.1007/978-3-031-37108-0_45&nbsp; .</p> <p>All calculations have been performed with&nbsp;Gaussian 09, Revision D.01.</p> <p>All structures have been optimized&nbsp;at B3LYP/aug-cc-pVTZ level of theory.</p>

opencc-by-4.0Oct 2023View details →
zenodo44/100

Optimized stationary points on the potential energy surfaces of the S+(4S) + SiH2(1A1) and HSiS+/SiSH+ + NH3 reactions

<p>This Zip file contains the cartesian coordinates of optimized stationary points on the&nbsp;potential energy surfaces (PESs) of three reactions:&nbsp;S<sup>+</sup>(<sup>4</sup>S) + SiH<sub>2</sub>(<sup>1</sup>A<sub>1</sub>), <sup>3</sup>HSiS<sup>+</sup> + NH<sub>3</sub>&nbsp;and&nbsp;<sup>3</sup>SiSH<sup>+</sup> + NH<sub>3</sub>.</p> <p>These PESs&nbsp;are part of our paper&nbsp;&ldquo;The S<sup>+</sup>(<sup>4</sup>S)+SiH<sub>2</sub>(<sup>1</sup>A<sub>1</sub>) Reaction: Toward the&nbsp;Synthesis of&nbsp;Interstellar SiS&rdquo;</p> <p>(<em>Lecture Notes in Computer Science</em> <strong>2022</strong>,&nbsp;13378, 233-245), that can be downloaded in&nbsp;https://doi.org/10.1007/978-3-031-10562-3_17 .</p> <p>All calculations have been performed with&nbsp; Gaussian 09, Revision D.01.</p> <p>All structures have been optimized&nbsp;at B3LYP/aug-cc-pV(T+d)Z level of theory.</p>

opencc-by-4.0Oct 2023View details →
zenodo44/100

Low-energy Museum Storage Buildings: Climate, Energy Consumption and Air Quality. Data Set for Final Data Report

<p>The 43 txt-files included in this dataset relate to the report: Ryhl-Svendsen, Jensen, B&oslash;hm, and Klenz Larsen (2012): <em>Low-energy Museum Storage Buildings: Climate, Energy Consumption and Air Quality. UMTS Research Project 2007</em>&ndash;<em>2011: Final Data Report</em>, Kgs. Lyngby: National Museum of Denmark, 122&nbsp;pp.</p> <p>The document <a href="https://zenodo.org/api/files/145584b0-46b5-4341-8b02-7dfea90fa97c/00_List-of-data-files.pdf?versionId=a3e9691f-6e73-4a7b-aaab-c8ccee7c419b">00_List-of-data-files.pdf</a> contain a full list of the data files with&nbsp;a description of their structure and content, and&nbsp;is the key to how the individual data files relate to the report.&nbsp;</p> <p>The research project focussed on four modern museum storage facilities in Denmark, for which the indoor climate, air quality, and the energy consumption of the climate control systems was measured at several locations, typically for a period of between two and four years. The storage facilities were Museum of Southwest Jutland&rsquo;s storage building in Ribe (&lsquo;Ribe&rsquo;), The Shared Storage Facility at The Centre for Preservation of Cultural Heritage in Vejle (&lsquo;Vejle&rsquo;), The Joint Storage Facility for museums in East Jutland/ Museum &Oslash;stjylland (&lsquo;Randers&rsquo;), and from The National Museum of Denmark the storage building Hall P at the &Oslash;rholm Storage Facility (&lsquo;&Oslash;rholm&rsquo;). For description of the sites, monitoring campaigns, and graphed data, the report should be consulted.</p> <p>For completeness, the report is included with the dataset (<a href="https://zenodo.org/api/files/145584b0-46b5-4341-8b02-7dfea90fa97c/Report_low-energy-museum-storage-buildings.pdf?versionId=44097d39-775b-4031-9e07-6978c68912a9">Report_low-energy-museum-storage-buildings.pdf</a>).</p>

opencc-by-4.0Oct 2023View details →
zenodo44/100

Optimized structures of selected stationary points on the potential energy surface of the HC3N + CN reaction

<p>This Zip file contains the cartesian coordinates of optimized stationary points of&nbsp;the HC<sub>3</sub>N + CN&nbsp;potential energy surface published in our article&nbsp;&ldquo;Semiempirical Potential in Kinetics Calculations on the HC<sub>3</sub>N + CN Reaction&rdquo; (<em>Molecules</em> <strong>2022</strong>, <em>27(7)</em>, 2297), that can be found in&nbsp;<a href="https://doi.org/10.3390/molecules27072297">https://doi.org/10.3390/molecules27072297</a>&nbsp;.</p> <p>All calculations have been performed with&nbsp; Gaussian 09, Revision D.01.</p> <p>All structures have been optimized&nbsp;at M06-2X/6-311+G(d,p) level of theory.</p>

opencc-by-4.0Sep 2023View details →
zenodo44/100

Supplemental Data for "Energy minimization of paired composite fermion wave functions in the spherical geometry"

<p>Includes extra data for "Energy minimization of paired composite fermion wave functions in the spherical geometry".</p>

opencc-by-4.0Sep 2023View details →
edi44/100

Mass and energy fluxes from the US-Jo2 AmeriFlux eddy covariance tower in Tromble Weir experimental watershed at the Jornada Basin LTER site, 2010-ongoing

This data package contains metadata for, and links to, 30-minute mass and energy flux data collected at an eddy covariance tower in the Tromble Weir Watershed area of the Jornada Basin in southern New Mexico, USA. These data are used to quantify the water and energy balances in a small experimental watershed, including observational studies to calculate groundwater recharge as a water balance residual, to build relations between soil moisture state and ET flux, and to quantify land-atmosphere interactions and improve our understanding of the eddy covariance method. Additionally, they have been used in modeling studies as a validation of model performance. The .csv files included in this package list and describe the data entities and variables present in data files archived at the AmeriFlux data repository (site US-Jo2; http://ameriflux.lbl.gov/sites/siteinfo/US-Jo2). The data at AmeriFlux include the 30-minute mass and energy fluxes calculated from 20 Hz data collected at the Tromble Weir Watershed tower. Instrument descriptions and detailed procedures are found in the references listed in the Methods section of this EDI package. This is an ongoing dataset that will be updated annually.

openCC (other)Jun 2020View details →
edi44/100

MCR LTER: Coral Reef: Growth and scaling of photosynthetic energy intake in Fungia concinna: Elahi & Edmunds 2007 JEMBE

For many marine invertebrates, the maximum size of an individual is influenced heavily by environmental factors and may be limited by energetic constraints. In this study, an energetic model developed originally for anemones was applied to the free-living scleractinian Fungia concinna (Verrill) from Moorea, French Polynesia to test the hypothesis that energetic constraints limit the size of this solitary coral. The modified model assumed that photosynthesis was the primary source of metabolic energy, and that metabolic costs were represented by aerobic respiration; these sources and sinks of energy were compared using daily energy budgets that were analyzed using double logarithmic regressions of energy against coral size. These data were published in Elahi, R. and P.J. Edmunds. 2007. Determinate growth and the scaling of photosynthetic energy intake in the solitary coral Fungia concinna (Verrill). Journal of Experimental Marine Biology and Ecology 349:183-193. and were part of the masters thesis of R. Elahi (2005). This material is based upon work supported by the U.S. National Science Foundation under Grant No. OCE 16-37396 (and earlier awards) as well as a generous gift from the Gordon and Betty Moore Foundation. Research was completed under permits issued by the French Polynesian Government (Délégation à la Recherche) and the Haut-commissariat de la République en Polynésie Francaise (DTRT) (Protocole d'Accueil 2005-2018). This work represents a contribution of the Moorea Coral Reef (MCR) LTER Site.

openCC (other)Feb 2012View details →
zenodo40/100

(POST) Socio-economic and cultural dataset in relation to Persuasive Strategies to boost Energy Efficiency and in the UK, Spain, Greece and Austria

<p>The dataset has been created from obtaining post-pilot answers from 106 participants of four different countries in the EU (the questionnaire can be studied in <strong>GreenSoul_Validation_Questionnaire-POST.pdf</strong>). It is composed by several factors which are explained in<strong> POST-coding.ods </strong>file. All these factors are contained in: &quot;<strong>POST-results-socio-economic-model.ods</strong>&quot; and &quot;<strong>POST-results-treatments-evaluation.ods</strong>&quot; along with their answers by participants.</p> <p>Finally, we provided a cleaned version of the dataset to study how can a researcher is able to forecast the ranking that a user will give to different persuasion strategies according to user profiles: &quot;<strong>POST-results-ranking-model.ods</strong>&quot;</p>

opencc-by-4.0Dec 2019View details →
zenodo40/100

Battery and water heater energy elasticity performance optimisation

<p>This dataset provides actual data demonstrating&nbsp;the INVADE European Union&nbsp;initiative (https://h2020invade.eu/) from the Bulgarian pilot situated in Albena resort, Bulgaria (https://albena.bg/). It represents results from two different approaches to&nbsp;energy elasticity - using a 200kWh industrial sized battery with a combination of a&nbsp;PV, as well as using water heaters with a combination of&nbsp;thermal solar collectors. For both approaches, the system takes into account the energy prices as listed in the Independent Bulgarian Energy Exchange (http://www.ibex.bg/en), as well as weather forecast for the expected energy production from the solar panels.</p> <p><strong>Battery.xlsx</strong>&nbsp;(16&nbsp;days&nbsp;worth of data for the battery&nbsp;as follows):</p> <ul> <li>Timestamp: the time stamp of the entered data point</li> <li>IBEX SpotPrice (EUR/MWh): the energy price for the current data point</li> <li>Consumption (kWh): the current&nbsp;energy consumption from the grid as taken from the energy meter into the facility</li> <li>ChargingPowerRegulation (kW): control signal received from the system to charge the battery</li> <li>DischargingPowerRegulation (kW): control signal received from the system to discharge&nbsp;the battery</li> <li>EnergyLevel (kWh): the energy level of the battery</li> <li>PV Production (kWh): the produced energy by the PV installation</li> <li>ActualSolarIrradiation (W/m^2): the current solar irradiance</li> <li>ActualTemperature (℃): the current temperature</li> </ul> <p><strong>WaterHeater.xlsx</strong>&nbsp;(1 month worth of data for the water heater as follows):</p> <ul> <li>Timestamp: the time stamp of the entered data point</li> <li>IBEX SpotPrice (EUR/MWh): the energy price for the current data point</li> <li>Consumption (kWh): the current&nbsp;energy consumption from the grid&nbsp;as taken from the energy meter into the facility</li> <li>EnergyLevelHeat (kWh): the current thermal energy level in the water boilers</li> <li>EnergyHeatCapacity (kWh): the current thermal energy capacity of the water boilers</li> <li>HeatProduction (kWh): the current thermal energy production by the solar thermal collectors</li> <li>ActualSolarIrradiation (W/m^2): the current solar irradiance</li> <li>ActualTemperature (℃): the current temperature</li> </ul> <p>Please, make all Creative Commons license&nbsp;attributions for usage of this dataset&nbsp;to &quot;Albena AD (https://albena.bg/)&quot;</p>

opencc-by-4.0Feb 2020View details →
zenodo40/100

Plummeting costs of renewables - Are energy scenarios lagging?

<p>Raw data for the working paper &quot;Plummeting costs of renewables - Are energy scenarios lagging?&quot;</p>

opencc-by-4.0Mar 2020View details →
zenodo40/100

Fig. 1 in Divergence in energy sources for Prochilodus lineatus (Characiformes: Prochilodontidae) in Neotropical floodplains

Fig. 1. Map of the floodplain of the Upper Paraná River, highlighting the areas sampled in this study. The subsystems sampled were A = Paraná River, B = Baía River and C = Ivinheima River. The numbers indicate sampled sites in each subsystem.

opencc-by-4.0Nov 2018View details →
zenodo40/100

Fig. 4 in Divergence in energy sources for Prochilodus lineatus (Characiformes: Prochilodontidae) in Neotropical floodplains

Fig. 4. The average percentage contribution of each carbon source in different subsystems. The width of arrows represents the strength of resource utilization in each environment studied (MB = microbial biomass).

opencc-by-4.0Nov 2018View details →
zenodo40/100

Benchmark set for relative free energy calculations

<p>Created by Christina Schindler and Daniel Kuhn, Merck KGaA, Darmstadt, Germany.</p> <p>December 2018</p> <p>Manuscript in preparation.</p> <p>Previously presented at Alchemical Free Energy Workshop 2019 in Goettingen, Germany.</p> <p>DOI: 10.5281/zenodo.3258925</p> <p>&nbsp;</p> <p>References for datasets used in benchmark</p> <p>CDK8<br> Schiemann, Kai, et al. &quot;Discovery of potent and selective CDK8 inhibitors from an HSP90 pharmacophore.&quot; Bioorganic &amp; medicinal chemistry letters 26.5 (2016): 1443-1451.</p> <p>DOI: 10.1016/j.bmcl.2016.01.062</p> <p>c-Met</p> <p>Dorsch, Dieter, et al. &quot;Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors.&quot; Bioorganic &amp; medicinal chemistry letters 25.7 (2015): 1597-1602.</p> <p>DOI: 10.1016/j.bmcl.2015.02.002<br> Eg5</p> <p>Schiemann, Kai, et al. &quot;The discovery and optimization of hexahydro-2H-pyrano [3, 2-c] quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5.&quot; Bioorganic &amp; medicinal chemistry letters 20.5 (2010): 1491-1495.</p> <p>DOI: 10.1016/j.bmcl.2010.01.110<br> Hif2a</p> <p>Wallace, Eli M., et al. &quot;A small-molecule antagonist of HIF2&alpha; is efficacious in preclinical models of renal cell carcinoma.&quot; Cancer research 76.18 (2016): 5491-5500.</p> <p>DOI: 10.1158/0008-5472.CAN-16-0473</p> <p>Dixon, Darryl David, et al. &quot;Aryl ethers and uses thereof.&quot; U.S. Patent No. 9,908,845. 6 Mar. 2018.</p> <p>URL: Google Patents<br> PFKFB3</p> <p>Boutard, Nicolas, et al. &quot;Discovery and Structure&ndash;Activity Relationships of N-Aryl 6-Aminoquinoxalines as Potent PFKFB3 Kinase Inhibitors.&quot; ChemMedChem 14.1 (2019): 169-181.</p> <p>DOI: 10.1002/cmdc.201800569<br> SHP2</p> <p>Chen, Ying-Nan P., et al. &quot;Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases.&quot; Nature 535.7610 (2016): 148.</p> <p>DOI:10.1038/nature18621</p> <p>Garcia Fortanet, Jorge, et al. &quot;Allosteric inhibition of SHP2: identification of a potent, selective, and orally efficacious phosphatase inhibitor.&quot; Journal of medicinal chemistry 59.17 (2016): 7773-7782.</p> <p>DOI: 10.1021/acs.jmedchem.6b00680</p> <p>Chen, Christine Hiu-tung, et al. &quot;1-pyridazin-/triazin-3-yl-piper (-azine)/idine/pyrolidine derivatives and compositions thereof for inhibiting the activity of shp2.&quot; U.S. Patent Application No. 15/110,498.</p> <p>URL: Google Patents</p> <p>&nbsp;</p> <p>SYK<br> Currie, Kevin S., et al. &quot;Discovery of GS-9973, a selective and orally efficacious inhibitor of spleen tyrosine kinase.&quot; Journal of medicinal chemistry 57.9 (2014): 3856-3873.</p> <p>DOI: 10.1021/jm500228a</p> <p>TNKS2<br> Buchstaller, Hans-Peter, et al. &quot;Discovery and Optimization of 2-Arylquinazolin-4-ones into a Potent and Selective Tankyrase Inhibitor Modulating Wnt Pathway Activity.&quot; Journal of medicinal chemistry 62.17 (2019): 7897-7909.</p> <p>DOI: 10.1021/acs.jmedchem.9b00656</p>

openmit-licenseAug 2019View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record