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Dataset results
289 results for “data reduction”
Data from: Meiotic drive does not cause condition-dependent reduction of the sexual ornament in stalk-eyed flies
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BFM50 Reduction Data
<p>This contains all the data from reducing the Biogeochemical Flux Model using the modified DRGEP method. This includes the plotting script, filer for the timer simulations, inputs used for the reduction for each scenario, and files for the verification of the modified DRGEP method.</p>
Data from: Encounter complexes and dimensionality reduction in protein-protein association
An outstanding challenge has been to understand the mechanism whereby proteins associate. We report here the results of exhaustively sampling the conformational space in protein–protein association using a physics-based energy function. The agreement between experimental intermolecular paramagnetic relaxation enhancement (PRE) data and the PRE profiles calculated from the docked structures shows that the method captures both specific and non-specific encounter complexes. To explore the energy landscape in the vicinity of the native structure, the nonlinear manifold describing the relative orientation of two solid bodies is projected onto a Euclidean space in which the shape of low energy regions is studied by principal component analysis. Results show that the energy surface is canyon-like, with a smooth funnel within a two dimensional subspace capturing over 75% of the total motion. Thus, proteins tend to associate along preferred pathways, similar to sliding of a protein along DNA in the process of protein-DNA recognition.
Data from: Single‐cell profiling screen identifies microtubule‐dependent reduction of variability in signaling
Populations of isogenic cells often respond coherently to signals, despite differences in protein abundance and cell state. Previously, we uncovered processes in the Saccharomyces cerevisiae pheromone response system (PRS) that reduced cell‐to‐cell variability in signal strength and cellular response. Here, we screened 1,141 non‐essential genes to identify 50 "variability genes". Most had distinct, separable effects on strength and variability of the PRS, defining these quantities as genetically distinct "axes" of system behavior. Three genes affected cytoplasmic microtubule function: BIM1, GIM2, and GIM4. We used genetic and chemical perturbations to show that, without microtubules, PRS output is reduced but variability is unaffected, while, when microtubules are present but their function is perturbed, output is sometimes lowered, but its variability is always high. The increased variability caused by microtubule perturbations required the PRS MAP kinase Fus3 and a process at or upstream of Ste5, the membrane‐localized scaffold to which Fus3 must bind to be activated. Visualization of Ste5 localization dynamics demonstrated that perturbing microtubules destabilized Ste5 at the membrane signaling site. The fact that such microtubule perturbations cause aberrant fate and polarity decisions in mammals suggests that microtubule‐dependent signal stabilization might also operate throughout metazoans.
Data from: Freshwater eutrophication drives sharp reductions in temporal beta diversity
Eutrophication has become one of the most widespread anthropogenic forces impacting freshwater biological diversity. One potentially important mechanism driving biodiversity changes in response to eutrophication is the alteration of seasonal patterns of succession, particularly among species with short, synchronous life cycles. We tested the hypothesis that eutrophication reduces seasonally driven variation in species assemblages by focusing on an understudied aspect of biodiversity: temporal beta diversity . We estimated the effect of eutrophication on by sampling benthic macroinvertebrate assemblages bimonthly for 2 years across 35 streams spanning a steep gradient of total phosphorus (P) and benthic algal biomass (as chlorophyll). Two widely used metrics of β diversity both declined sharply in response to increasing P and chl, regardless of covariates. The most parsimonious explanatory model for included an interaction between P and macroinvertebrate biomass, which revealed that was lower when macroinvertebrate biomass was relatively high. Macroinvertebrate biomass explained a greater amount of deviance in at lower to moderate concentrations of P, providing additional explanatory power where P concentration alone was unable to fully explain declines in. Chl-explained similar amounts of deviance in comparison to the best P model, but only when temperature variability, which was positively related to, also was included in the model. Declines in suggest that nutrient enrichment decreases the competitive advantage that specialists gain by occupying particular temporal niches, which leads to assemblages dominated by generalists that exhibit little seasonal turnover. The collapse of seasonal variation in assemblage composition we observed in our study suggests that treating dynamic communities as static assemblages is a simplification that may fail to detect the full impact of anthropogenic stressors. Our results show that eutrophication leads to more temporally homogenous communities and therefore degrades a fundamental facet of biodiversity.
Attributing agnostically-detected large reductions in road CO2 emissions to policy mixes (code and data)
<p>Data and code to reproduce the main results of the paper.</p>
Data for Concurrent Time-Series Selections Using Deep Learning and Dimension Reduction
<p>This data set has the ground truth labels for the publication "Concurrent Time-Series Selections Using Deep Learning and Dimension Reduction".</p> <p>The raw tri-axial accelerometry data is available as a separate data set:<br> dataset doi: 10.5281/zenodo.5500402<br> original paper for that data set doi: 10.3354/esr00084</p> <p>The data set here (available at the doi: 10.5281/zenodo.5503031) has the ground truth labels in 4 columns.</p> <p>The first and second columns are the start and end of the label in normalized coordinates [-1,1] representing the x-axis mouse clicks that created the label.<br> The third and fourth columns are transformed back to the data x-axis [0,173255].</p> <p>1D_1 are the labels for surfacing feature<br> 1D_2 are the labels for diving feature</p> <p>We also provide a recording of one of the participants in the user study.</p>
Efficient Configuration Tuning for Big-Data Software Systems via Configuration Space Reduction
<p>Efficient Configuration Tuning for Big-Data Software Systems via Configuration Space Reduction (Supplementary Material)</p>
Data from: Freshwater eutrophication drives sharp reductions in temporal beta diversity
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Data from: Single‐cell profiling screen identifies microtubule‐dependent reduction of variability in signaling
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Data from: Genome reduction and microbe-host interactions drive adaptation of a sulfur-oxidizing bacterium associated with a cold seep sponge
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Data from: Encounter complexes and dimensionality reduction in protein-protein association
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Data from: Interaction between the oculomotor and postural systems during a dual-task: compensatory reductions in head sway following visually-induced postural perturbations promote the production of accurate double-step saccades in standing human adults
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Data from: Genome reduction uncovers a large dispensable genome and adaptive role for copy number variation in asexually propagated Solanum tuberosum
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Expression data from breast tumors and reduction mammoplasty explants
GEO Series GSE25407. Homo sapiens. 10 samples. Type: Expression profiling by array.
Data from: Natural history and long-term effects of variant protein reduction in non-V30M ATTR amyloidosis
No abstract
Simulation Data for Comparison of Bias Reduction Methods for Logistic Regression
<p>Simulation Results for "Comparison of Bias Reduction Methods for Logistic Regression</p> <p>Resultsp.RData include the raw simulation results for p = 1, 4, 8</p> <p>Statsp.RData include the summarized simulation results for p = 1, 4, 8</p>
Data from: Natural history and long-term effects of variant protein reduction in non-V30M ATTR amyloidosis
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Raw data for the article "Bi2Se3-MWCNT heterostructures as catalysts for CO2 photothermal reduction"
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Analysed data for poster presentation "Dielectric barrier discharge plasma reduction of iron oxides"
<p>Native surface oxides, which usually contaminate metals in ambient atmosphere, limit the performance in industrial applications like coating or welding. Different deoxidation techniques were developed to remove such oxide layers. Promising results were obtained for dielectic barrier discharge (DBD) hydrogen plasmas in deoxidation of copper at 20 °C and 100 – 1000 hPa. In this study, we report the application of a DBD plasma for deoxidation of natively oxidized iron surfaces in an Ar/H2 atmosphere at 100 and 1000 hPa. Plasma treatments were performed at a discharge voltage of 10 kV and a frequency of 8.8 kHz at room temperature (RT) as well as in the combination with heating<br> </p>
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.