Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
276
datasets available to search
ShareScore release 0.9.0
Dataset results
276 results for “gene drive”
CHCHD2 gene KO effect in iPSC drived motor neurons
GEO Series GSE133764. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
CDK8 Mediator kinase drives colon cancer hepatic metastasis by regulating gene expression of the matrix metalloproteinase network [Illumina]
GEO Series GSE104963. Mus musculus. 2 samples. Type: Expression profiling by array.
Simultaneous Single-cell Genome and Transcriptome Sequencing with Digital Microfluidics Identifying Essential Driving Genes
GEO Series GSE199010. Homo sapiens. 91 samples. Type: Expression profiling by high throughput sequencing; Other.
Anti-CD137 drives early epigenetic remodeling of Tex cell associated genes
GEO Series GSE228271. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
CHCHD10 gene KO effect in iPSC drived motor neurons
GEO Series GSE133763. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Chromatin repression by PRC2 results in reduced gene expression driving key features of CD8 T cell exhaustion [RNA-seq]
GEO Series GSE263885. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
IRF1 activation and target gene induction drive all-trans retinoic acid efficacy in acute promyelocytic leukemia with potential as a predictive indicator for cancer treatment
GEO Series GSE292653. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
CDK8 Mediator kinase drives colon cancer hepatic metastasis by regulating gene expression of the matrix metalloproteinase network
GEO Series GSE104970. Mus musculus. 6 samples. Type: Genome variation profiling by SNP array.
Oncofetal gene reactivation drives EZH2-mutant myeloid leukemia pathogenesis
GEO Series GSE173497. Mus musculus. 59 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array.
Snf2L drives Plasmodium just-in-time gene expression and gametocytogenesis
GEO Series GSE237217. Plasmodium falciparum. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
CDK8 Mediator kinase drives colon cancer hepatic metastasis by regulating gene expression of the matrix metalloproteinase network [Affymetrix]
GEO Series GSE103346. Mus musculus. 4 samples. Type: Expression profiling by array.
Virus modified paraspeckles are essential hubs for gene expression and their formation drives genomic instability
GEO Series GSE277122. Homo sapiens. 6 samples. Type: Other.
Chromatin repression by PRC2 results in reduced gene expression driving key features of CD8 T cell exhaustion [Cut & Run]
GEO Series GSE263937. Mus musculus. 14 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
OTX2 drives medulloblastoma proliferation via direct regulation of cell cycle genes and inhibits differentiation
The transcription factor OTX2 has been implicated as an oncogene in medulloblastoma, which is the most common malignant brain tumor in children. It is highly expressed in most medulloblastomas and amplified in a subset of them. The role of OTX2 in medulloblastoma and its downstream targets are unclear. Therefore, we generated D425 medulloblastoma cells in which we can silence endogenous OTX2 by inducible shRNA. Silencing of OTX2 strongly inhibited cell proliferation and resulted in a neuronal-like differentiation.
Unraveling a mechanism driving poor-prognosis prostate cancer: overexpression of the DNA repair gene, ribonucleotide reductase small subunit M2
GEO Series GSE118845. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Chromatin repression by PRC2 results in reduced gene expression driving key features of CD8 T cell exhaustion
GEO Series GSE263938. Mus musculus. 34 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.