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Dataset results
2,236 results for “inhalation”
Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU1)
ClinicalTrials.gov study NCT05312385. IPD Sharing: NO. Countries: 1. Publications: 16.
Montelukast and Inhaled Nasal Steroid Tx in Adult Obstructive Sleep Apnea (OSA)
ClinicalTrials.gov study NCT01089647. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Acute Airway Vascular Smooth Muscle Effects of Inhaled Budesonide
ClinicalTrials.gov study NCT01219738. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Long Term Safety of Tobramycin Inhalation Powder in Patients With Cystic Fibrosis
ClinicalTrials.gov study NCT01519661. IPD Sharing: Not stated. Countries: 10. Publications: 1.
Evaluation of Tiotropium 2.5 and 5 mcg Once Daily Delivered Via the Respimat® Inhaler Compared to Placebo and Salmeterol HydroFluoroAlkane (HFA) Metered Dose Inhaler (MDI) (50 mcg Twice Daily) in Pati
ClinicalTrials.gov study NCT01172808. IPD Sharing: Not stated. Countries: 11. Publications: 5.
To Assess the Safety, Tolerability and Pharmacokinetics of AZD5634 Following Inhaled and Intravenous (IV)Dose Administration
ClinicalTrials.gov study NCT02679729. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Inhaled Selective Pulmonary Vasodilators for Advanced Heart Failure Therapies and Lung Transplantation Outcomes
ClinicalTrials.gov study NCT03081052. IPD Sharing: NO. Countries: 1. Publications: 2.
Effect & Safety of Inhaled Isoflurane vs IV Midazolam for Sedation in Mechanically Ventilated Children 3-17 Years Old
ClinicalTrials.gov study NCT04684238. IPD Sharing: NO. Countries: 5. Publications: 16.
Sixty-minute inhalation of molecular hydrogen decreases blood oxygen saturation but does not alter autonomic cardiac regulation at rest in healthy females: A randomized, double-blind, placebo-controlled crossover study
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Data from 90-day quantitative inhalation toxicology study evaluating the dose-response and fate in the lung and pleura of chrysotile-containing brake dust
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Personalized inhaled bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa in cystic fibrosis
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Increased vulnerability to atrial and ventricular arrhythmias caused by different types of inhaled tobacco or marijuana products
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Neural and subjective effects of inhaled DMT in natural settings
<p>Raw EEG data (DMT, eyes open and eyes closed) and psychometric scales for the 35 participants of "Neural and subjective effects of inhaled DMT in natural settings".</p>
Short-term responses to high-dose inhaled corticosteroid treatment in patients with chronic obstructive pulmonary disease having a fractional nitric oxide concentration over 35 parts per billion: a single-center pre-post study
<p>Background: There is currently no strategy to identify chronic obstructive pulmonary disease (COPD) patients whose pulmonary function could benefit from inhaled corticosteroids. This study investigates whether a 28-day regime of inhaled corticosteroids improves pulmonary function test results among chronic obstructive pulmonary disease patients having a fractional exhaled nitric oxide concentration > 35 parts per billion.<br> Methods: This was a single-center one-arm pre–post trial. Chronic obstructive pulmonary disease patients with a fractional exhaled nitric oxide concentration > 35 parts per billion treated at our institution from September 2018 to August 2019 were included. Each patient was administered budesonide (200 μg, 8 puffs daily) for 28 days. The primary outcome measure was the difference between the values of forced expiratory volume in 1 s (FEV1) at baseline and 28 days after inhaled corticosteroid initiation. Secondary outcomes included differences of Chronic Obstructive Pulmonary Disease Assessment Test scores, %FEV1, and that between the percent forced vital capacity at baseline and 28 days after inhaled corticosteroid initiation.<br> Results: Twenty patients were included; all patients completed the 28-day inhaled corticosteroid regime. The mean difference in FEV1 between day 1 and 28 days after inhaled corticosteroid initiation was 340 mL (95% confidence interval: −100 to 770 mL; p = 0.122). The mean differences in secondary outcomes were: % forced vital capacity , −0.16% (95% confidence interval: −2.84 to 2.53%; p = 0.905); %FEV1, 1.63% (95% confidence interval: −4.56 to 7.81%; p = 0.589); Chronic Obstructive Pulmonary Disease Assessment Test score, −2.50 (95% confidence interval: −5.72 to 0.72; p = 0.121).<br> Conclusion: The 28-day course of inhaled corticosteroids showed no significant difference in FEV1 for chronic obstructive pulmonary disease patients having fractional exhaled nitric oxide concentration > 35 parts per billion.<br> </p>
Estimating Inhaled Nitrogen Dioxide from the Human Biometric Response
<p>Data and code in Jupyter notebook to estimated inhaled NO2 using biometrics of a person for a currently unpublished work titled " Estimating Inhaled Nitrogen Dioxide from Human Biometric Response." By making use of number of biometric variables we can to some extent estimate the inhaled NO2, but further confirmation is required. </p>
Evaluation of in vitro rat and human airway epithelial models for acute inhalation toxicity testing
<p><em>In vivo</em> models (mostly rodents) are currently accepted by regulatory authorities for assessing acute inhalation toxicity. Considerable efforts have been made in recent years to evaluate in vitro human airway epithelial models (HAEM) as replacements for <em>in vivo</em> testing. In the current work, an organotypic <em>in vitro</em> rat airway epithelial model (RAEM), rat EpiAirway™, was developed and characterized to allow a direct comparison with the available HAEM, human EpiAirway™, in order to address potential interspecies variability in responses to harmful agents. The rat and human models were evaluated in two independent laboratories with 14 reference chemicals, selected to cover a broad range of chemical structures and reactive groups, as well as known acute animal and human toxicity responses, in three replicate rounds of experiments. Toxicity endpoints included changes in tissue viability (MTT assay), epithelial barrier integrity (TEER, transepithelial electrical resistance), and tissue morphology (histopathology). The newly developed rat EpiAirway™ model produced reproducible results across all replicate experiments in both testing laboratories. Furthermore, a high level of concordance was observed between the RAEM and HAEM toxicity responses (determined by IC<sub>25</sub>) in both laboratories, with R<sup>2</sup> = 0.78 and 0.88 when analyzed by TEER; and R<sup>2</sup> = 0.92 for both when analyzed by MTT. These results indicate that rat and human airway epithelial tissues respond similarly to acute exposures to chemicals. The new in vitro RAEM will help extrapolate to<em> in vivo</em> rat toxicity responses and support screening as part of a 3Rs program.</p>
Long Term Administration of Inhaled Dry Powder Mannitol In Cystic Fibrosis - A Safety and Efficacy Study
ClinicalTrials.gov study NCT00446680. IPD Sharing: Not stated. Countries: 3. Publications: 3.
Study of Inhaled Corticosteroid Plus Montelukast Compared With Inhaled Corticosteroid Therapy Alone in Patients With Chronic Asthma (0476-386)
ClinicalTrials.gov study NCT00666679. IPD Sharing: NO. Countries: 0. Publications: 1.
Study of Inhaled Glucocorticosteroids/Long-Acting Bronchodilator Drugs in Subjects With Asthma That Have Been Taking Inhaled Glucocorticosteroids (Study P04705AM1)
ClinicalTrials.gov study NCT00424008. IPD Sharing: NO. Countries: 0. Publications: 2.
Inhaled Iloprost for Suspected COVID-19 Respiratory Failure
ClinicalTrials.gov study NCT04445246. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.