Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
623
datasets available to search
ShareScore release 0.9.0
Dataset results
623 results for “lipid metabolism”
Lipid droplets are a metabolic vulnerability in melanoma
GEO Series GSE201378. Danio rerio. 7 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional Analysis of Lipid Metabolism Controlling Enzymes in Bovine Ovary
GEO Series GSE149151. Bos taurus. 20 samples. Type: Expression profiling by array.
Mice model for 15q11-13 duplication syndrome show late onset obesity and altered lipid metabolism
GEO Series GSE58191. Mus musculus. 6 samples. Type: Expression profiling by array.
Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer
GEO Series GSE176454. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Extensive reprogramming of lipid metabolism in the liver during West Nile virus infection in mice highlights novel aspects of disease pathophysiology [liver]
GEO Series GSE242980. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Lamin A/C regulates lipid metabolism and inflammation: insights from models of familial partial lipodystrophy 2 sub1
GEO Series GSE311533. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Insights into microbial modulation of host peripheral lipid and glucose metabolism using mouse gut organoids
GEO Series GSE59644. Mus musculus. 32 samples. Type: Expression profiling by array.
Identification of early transcriptome-based biomarkers related to lipid metabolism in peripheral blood mononuclear cells of rats nutritionally programmed for improved metabolic health
GEO Series GSE119955. Rattus norvegicus. 23 samples. Type: Expression profiling by array.
Aberrant lipid metabolism in macrophages is associated with granuloma formation in sarcoidosis
GEO Series GSE251802. Homo sapiens. 28 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic Analysis of Small Extracellular Vesicles (sEVs) from Mouse Liver Tissue Across Age Groups: Implications for Aging and Lipid Metabolism
GEO Series GSE285729. Mus musculus. 25 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Mitofusins Regulate Lipid Metabolism to Mediate the Development of Lung Fibrosis
GEO Series GSE115730. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.
Nonvesicular sterol transport is a metabolic immune checkpoint that guards dietary lipid uptake (scRNA-Seq)
GEO Series GSE277138. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) [RNA-s
GEO Series GSE238201. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
HOXB13 inhibits lipid metabolism through HDAC3-mediated epigenetic reprogramming
GEO Series GSE153586. Homo sapiens. 42 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Host Genetics and Gut Microbiota Influence Lipid Metabolism and Inflammation: Potential implications for ALS Pathophysiology in SOD1 G93A Mice
GEO Series GSE278875. feces metagenome. 101 samples. Type: Other.
Functional multi-organelle units control inflammatory lipid metabolism of macrophages
GEO Series GSE235484. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Niclosamide as a chemical probe for analyzing SARS-CoV-2 modulation of host cell lipid metabolism
<p>SARS-CoV-2 subverts host cell processes to facilitate rapid replication and dissemination, and this leads to pathological inflammation. We used niclosamide (NIC), a poorly soluble anti-helminth drug identified for repurposed treatment of COVID-19, which activates the cells' autophagic and lipophagic processes as a chemical probe to determine if it can modulate the host cell's total lipid profile that would otherwise be either amplified or reduced during SARS-CoV-2 infection. Through parallel lipidomic and transcriptomic analyses we observed massive reorganization of lipid profiles of SARS-CoV-2 infected Vero E6 cells, especially with triglycerides, which were elevated early during virus replication, but decreased thereafter, as well as plasmalogens, which were elevated at later timepoints during virus replication, but were also elevated under normal cell growth. These findings suggested a complex interplay of lipid profile reorganization involving plasmalogen metabolism. We also observed that NIC treatment of both low and high viral loads does not affect virus entry. Instead, NIC treatment reduced the abundance of plasmalogens, diacylglycerides, and ceramides, which we found elevated during virus infection in the absence of NIC, resulting in a significant reduction in the production of infectious virions. Unexpectedly, at higher viral loads, NIC treatment also resulted in elevated triglyceride levels, and induced significant changes in phospholipid metabolism. We posit that future screens of approved drugs should prioritize compounds that effectively counter SARS-CoV-2 subversion of lipid metabolism, thereby reducing virus replication, egress, and the subsequent regulation of key lipid mediators of pathological inflammation.</p>
Lipid and Glycogen Metabolism in Patients With Impaired Glucose Tolerance and Calcium Sensing Receptor Mutations
ClinicalTrials.gov study NCT02023489. IPD Sharing: NO. Countries: 1. Publications: 0.
Is There a Metabolic Effect of Cinnamon on HbA1c, Blood Pressure and Serum Lipids in Type 2 Diabetes Mellitus?
ClinicalTrials.gov study NCT00846898. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Postprandial Lipid Metabolism in Patients With Hypertriglyceridemia and Normo-lipidemic Controls: Medium Chain Fatty Acids (MCT) in Comparison to Long-chain, Saturated Fatty Acids (SFA) and Mono-unsat
ClinicalTrials.gov study NCT03846908. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.