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4,566 results for “marker”
FIG. 7 in Gaming and divination pieces, markers of ownership, or all three? Zooarchaeology and the interpretation of knuckle bones found in tombs of the Iberian necropolis of El Poblado (Coimbra del Barranco Ancho, Murcia, Spain)
FIG. 7. — Knuckle bones found in Tomb 70. Scale bar: 2 cm. Photo credit: J. Gómez Carrasco.
FIG. 5. — Tomb 46 in Gaming and divination pieces, markers of ownership, or all three? Zooarchaeology and the interpretation of knuckle bones found in tombs of the Iberian necropolis of El Poblado (Coimbra del Barranco Ancho, Murcia, Spain)
FIG. 5. — Tomb 46, perforated knuckle bone. Scale bar: 1 cm. Photo credit: P. Thomas.
FIG. 2 in Gaming and divination pieces, markers of ownership, or all three? Zooarchaeology and the interpretation of knuckle bones found in tombs of the Iberian necropolis of El Poblado (Coimbra del Barranco Ancho, Murcia, Spain)
FIG. 2. — View of the Coimbra del Barranco Ancho site. Photo credit:J. M. García Cano.
FIG. 1 in Gaming and divination pieces, markers of ownership, or all three? Zooarchaeology and the interpretation of knuckle bones found in tombs of the Iberian necropolis of El Poblado (Coimbra del Barranco Ancho, Murcia, Spain)
FIG. 1. — Location of the Coimbra del Barranco Ancho site.
ISSR markers in five North American Sceptridium species
<p>Relationships among North American <em>Sceptridium </em>(sensu Škoda) species are often difficult to assess because of few stable distinguishing characters and high intraspecific variability. We used ISSR-PCR to examine relationships among four samples of <em>Holubiella</em>, 24 samples representing four diploid North American Sceptridium species, and a Russian <em>Sceptridium </em>sample. Nine ISSR primers yielded 147 polymorphic loci. We generated three neighbor-joining dendrograms using a Jaccard, Nei & Li, or Dice coefficient. All three coefficients cluster based solely on the presence of bands and not the absence. ISSR data analyses across all three coefficients were consistent with published analyses of DNA sequence data in supporting <em>Holubiella </em>as sister to all <em>Sceptridium </em>species sampled. Sister group relationships among the four <em>Sceptridium </em>species were not consistent across all three neighbor-joining analyses, and bootstrap support was generally low. However, 26 of the 29 samples consistently clustered with other samples of similar morphology, and these clusters generally supported current species concepts. In taxa such as <em>Sceptridium </em>with low DNA sequence variability among species, ISSR-PCR may provide an important tool for evaluating morphologically defined species, but additional data are necessary for establishing robust hypotheses of phylogenetic relationships. </p>
Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health
<p>This repository houses fully-adjusted methylome-wide association study (MWAS) summary statistics for 4,231 SomaScan protein measurements. These were generated as part of the study titled ‘Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health’ by Gadd <em>et al</em>. The Stratifying Resilience and Depression Longitudinally (STRADL) cohort used in this study is a subset of individuals from Generation Scotland: The Scottish Family Health Study. There were 744 individuals with complete protein and DNA methylation measurements available at 772,619 CpG probes. MWAS were performed with protein residuals as the outcome and DNA methylation as the exposure, using the Omics-data-based complex trait analysis (OSCA) software.</p> <p>Fully-adjusted models were run using M-values that were adjusted for age, sex, DNA methylation-derived immune cell estimates, depression status, DNA methylation batch and set, body mass index and a DNA methylation-derived smoking score. Protein levels were rank-based inverse normalised and scaled to have a mean of 0 and standard deviation of 1. Protein levels were residualised by age, sex, available pQTLs, technical covariates and 20 genetic principal components.</p> <p>Four of the 4,235 protein MWAS models did not converge (15509-2 - NAGLU, 15584-9 - CFHR2, 4407-10 - MST1 and 6402-8 - PILRA). Therefore, summary statistics are provided for 4,231 protein levels.</p> <p>Each protein MWAS summary statistics file has been saved with the following naming system: "MWAS_SeqId_Protein_gene.csv". For example, the protein with gene name CRYBB2 and SeqId 10000-28 has the following file name: "MWAS_10000-28_CRYBB2.csv".</p> <p>The SeqIds, UniProt codes, gene names and full UniProt names can be found in "annotation_formatted_for_paper.csv" and the full summary statistics are found within "compressed-protein-ewas.tar.gz".</p> <p>Please contact either <a href="mailto:riccardo.marioni@ed.ac.uk">riccardo.marioni@ed.ac.uk</a> or <a href="mailto:danni.gadd@ed.ac.uk">danni.gadd@ed.ac.uk</a> for any queries. All code is available at the following Github repository: <a href="https://github.com/DanniGadd/Epigenome-and-phenome-wide-study-of-brain-health-outcomes">https://github.com/DanniGadd/Epigenome-and-phenome-wide-study-of-brain-health-outcomes</a>.</p>
Code and data for "Discovery and validation of tissue-specific DNA methylation as noninvasive diagnostic markers for colorectal cancer".
<p>Code and data for "<strong>Discovery and validation of tissue-specific DNA methylation as noninvasive diagnostic markers for colorectal cancer</strong>".</p> <ul> <li> <p>The publicly available datasets supporting the conclusions of this article are available in the Gene Expression Omnibus repository (<a href="https://www.ncbi.nlm.nih.gov/geo/">https://www.ncbi.nlm.nih.gov/geo/</a>) and UCSC Xena Browser (TCGA, <a href="https://xena.ucsc.edu/">https://xena.ucsc.edu/</a>).</p> </li> </ul>
PD1+CD8+ cells are an independent prognostic marker in patients with head and neck cancer
<p><strong>Data open:</strong> file with parametres used for the multivariate evaluation. </p>
Nuclear genetic diversity and structure of Anastrepha ludens wild populations evidenced by microsatellite markers
<p class="MsoNormal"><span>The Mexican fruit fly, <em>Anastrepha ludens </em>is an important pest that causes widespread damage to a number of fruit crops in Mexico. The Sterile Insect Technique (SIT) is commonly used for its control. However, the existence of natural barriers can give rise to a population structure in neutral loci and possibly behavioral or adaptive traits that interfere with SIT. For this reason, it is important to understand the genetic diversity and structure of<em> A. ludens </em>populations and to better understand the evolutionary ecology and population processes in view of possible expansions and possible host shifts due to climate change. We genotyped nine nuclear DNA (nDNA) microsatellite loci among fruit fly populations collected from five biogeographic areas within Mexico, Mexican Plateau, the Northeastern Coastal Plain, the Pacific Coast, the Gulf Coast of Mexico, the Soconusco and a laboratory strain. The nuclear genetic diversity was moderate (from <em>H</em>e = 0.34 to <em>H</em>e = 0.39) within the wild mexfly population. We found that populations were clustered in three genetic groups (<em>K</em>=3). The diversity and genetic structure of <em>A. ludens</em> are produced by environmental and geological conditions as well as local conditions like anthropogenic perturbation which would produce population expansion and the existence of possible predators that would affect the population density. Gene flow showed recent migration among populations. The laboratory strain showed less diversity than the wild samples. Large values of current and ancestral population size suggest high resistance to climatic changes, probably due to biological attributes, such as its polyphagous, multivoltine and high dispersal characteristics. In particular ecosystem fragmentation and perturbation as well as the existence of new plant hosts all of which would probably increase the abundance of flies.</span></p>
De novo developed microsatellite markers in gill parasites of the genus Dactylogyrus (Monogenea)
<p class="MsoBodyText">Approaches using microsatellite markers are considered the gold standard for modern population-genetic studies. However, though they have found application in research into various platyhelminth taxa, they remained substantially underutilized in the study of monogeneans. In the present study, a newly-developed set of 24 microsatellite markers was used to investigate the genetic diversity of the generalist monogenean species <i>Dactylogyrus vistulae</i>. The analyzed parasite specimens were collected from 13 cyprinoid species from 11 sites in the Apennine and Balkan peninsulas. A total of 159 specimens were genotyped at each of the loci and the number of alleles per locus ranged from 2 to 16, with a mean number of 6.958 alleles per locus. Exceptionally high genetic diversity was observed among <i>D. vistulae </i>individuals in the southern Balkans (mean N<sub>A </sub>per locus = 3.917), suggesting that generalist <i>D. vistulae </i>expanded from the south to the north in the Balkans and later putatively into central Europe. The initial clustering analysis divided all investigated specimens into three major clusters; however, the results of the subsequent analyses revealed the existence of various subpopulations, suggesting that the population structure of <i>D. vistulae </i>is associated with the diversification of their cyprinoid hosts. In addition, the partition of the parasite population was observed in regions of the sympatric occurrence of two host species, indicating that these hosts may represent a barrier to gene flow, even for generalist parasite species.</p>
CLDF dataset derived from Tang and Her's "Quantitative typological data on classifiers and plural markers" from 2019
<p><strong>Tang, Marc and One-Soon Her. 2019. Insights on the Greenberg-Sanches-Slobin Generalization: Quantitative typological data on classifiers and plural markers. Folia Linguistica, 53(2): 297-331. https://doi.org/10.1515/flin-2019-2013.</strong></p>
CLDF dataset derived from Auderset's "Interrogatives as relativization markers in Indo-European" from 2020
<p><strong>Sandra Auderset. (2020). CLDF dataset from "Interrogatives as relativization markers in Indo-European” (Version v1.0) [Data set]. Zenodo. http://doi.org/10.5281/zenodo.4071139.</strong></p>
Native American Territory Marker High Res
Stones such as this were used to mark territories for Native American Tribes. 105 images, Canon EOS 80D, 35mm, F/16, ISO 100, Agisoft Metashape, Windows 10. Source: Objaverse 1.0 / Sketchfab
City Of London Dragon Boundary Marker
One of the 13 dragon topped boundary markers of the City of London. This one is on Goswell Road near Baltic Street West. Date: 1960s https://en.wikipedia.org/wiki/Dragon_boundary_mark 153 photos taken in June 2020 with a Sony a6000 and processed in Reality Capture. Source: Objaverse 1.0 / Sketchfab
St Pancras Parish Marker
A parish boundary marker on Purchese Street (south end, west side), Camden, London. 83 photos taken in April 2021 with a Sony a6000 and processed in Reality Capture. Source: Objaverse 1.0 / Sketchfab
Garreg Lwyd Marker Stone
A probably natural [marker stone](https://www.megalithic.co.uk/article.php?sid=26852) on the [Brecon Beacons](https://en.wikipedia.org/wiki/Garreg_Lwyd_(Black_Mountain)) in South Wales but with some interesting alignments to local features. Created from 56 photos using [openMVG](https://github.com/openMVG/openMVG) and [openMVS](https://github.com/cdcseacave/openMVS). Source: Objaverse 1.0 / Sketchfab
Key West Southernmost Pt. Marker After Hurricane
The marker at the Southernmost Point of the continental USA at Key West, Florida was damged by Hurricane Irma on September 10, 2017. Though the wind and waves stripped it of some of its paint, the marker stood strong - a symbol of the resilience of City of Key West and the greater Florida Keys community. Source: Objaverse 1.0 / Sketchfab
Clissold Park Boundary Marker
A metal boundary marker against the fence on the west side of Clissold Park, London. It marks the boundary between Stoke Newington Boundary and the Parish of Hornsey. It reads: "1887 - HORNSEY PARISH - No 175 - GILBERT ROBINS - HENRY REID". The rest is unreadable. 193 photos taken in June 2021 with a Sony a6000 and processed in Reality Capture. Source: Objaverse 1.0 / Sketchfab
Regents Park Boundary Marker 3
A parish boundary marker stone in Regents Park, London. It marked the boundary between St Marylebone and St Pancras. See map below for location (3). 93 photos taken in July 2020 with a Sony a6000 and processed in Reality Capture. Source: Objaverse 1.0 / Sketchfab
Regents Park Parish Boundary Markers 8
Two parish boundary markers on the South East edge of Regents Park, London. See map below for location (8). Photos taken in February 2019 with a Sony a6000 and processed in Agisoft Metashape. Source: Objaverse 1.0 / Sketchfab
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.