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3,255 results for “Pancreatic Cancer”
The promising miRNAs, Let-7b-5p and miR-24-3p, have the potential to serve as therapeutic agents targeting pancreatic cancer stem cells.
GEO Series GSE294243. Homo sapiens; synthetic construct. 4 samples. Type: Non-coding RNA profiling by array.
Connectivity Mapping-based Identification and Pre-clinical Evaluation of ISOX: A Novel Therapeutic for Pancreatic Cancer
GEO Series GSE240597. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Pancreatic cancer cells require the transcription factor MYRF (Myelin Regulatory Factor) to maintain ER homeostasis (ChIP-Seq).
GEO Series GSE145627. Homo sapiens. 11 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Targetting CD24 for treatment of colorectal and pancreatic cancer by monoclonal antibodies or siRNA
GEO Series GSE15102. Homo sapiens. 8 samples. Type: Expression profiling by array.
Long non-coding RNAs associated with mitogen-activated protein kinase in pancreatic cancer cells.
GEO Series GSE216710. Homo sapiens. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Expression of the membrane tetraspanin claudin 18 on cancer cells promotes T lymphocyte infiltration and antitumor immunity in pancreatic cancer
GEO Series GSE230868. Mus musculus. 6 samples. Type: Expression profiling by array.
Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation (ChIP-seq)
GEO Series GSE140481. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Pancreatic cancer biomarkers in mouse saliva
GEO Series GSE47811. Mus musculus. 12 samples. Type: Expression profiling by array.
Coordinated transcriptional and catabolic programs support iron dependent adaptation to RAS-MAPK pathway inhibition in pancreatic cancer
GEO Series GSE206269. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Transcriptome analysis of EYA2 non-expressing pancreatic cancer cell lines with stable transfectant overexpressing EYA2
GEO Series GSE33282. Homo sapiens. 8 samples. Type: Expression profiling by array.
The chromatin protein Nupr1 regulates RelB-dependent NF-kB events necessary for pancreatic cancer development
GEO Series GSE35463. Homo sapiens. 14 samples. Type: Expression profiling by array.
Targeting an RNA polymerase II-associated PHF5A transcriptional subcomplex with a KMT2A-WDR5 inhibitor impairs self-renewal and tumorigenicity of pancreatic cancer stem cells
GEO Series GSE217332. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer [ChIP-seq]
GEO Series GSE238197. Homo sapiens. 51 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Direct cell-to-cell transfer in stressed tumor microenvironment aggravates tumorigenic or metastatic potential in pancreatic cancer
GEO Series GSE201876. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Pachymic acid inhibits growth and induces apoptosis of pancreatic cancer in vitro and in vivo by targeting ER stress
GEO Series GSE64111. Homo sapiens. 8 samples. Type: Expression profiling by array.
S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells [HG-U133A]
GEO Series GSE19279. Homo sapiens. 15 samples. Type: Expression profiling by array.
Genome-Wide Analysis of cell-free DNA Methylation Profiling for the Early Diagnosis of Pancreatic Cancer
<p>This dataset mainly contains analysis pipeline and R codes used in the corresponding paper。</p>
Cachexia-induced reprogramming of visceral organ metabolism by human pancreatic cancer xenografts
<p>We have uploaded the raw MRS data used in this study. The data were obtained through dual-phase extraction from the heart, lungs, kidneys, pancreas, liver, and spleen samples. Each sample was reconstituted in 650 μL of phosphate-buffered D₂O (90:10 D₂O:H₂O, pH 7.4) with trimethylsilylpropanoic acid (TSP), and analyzed by ¹H MRS.All spectra were acquired using a Bruker 750 MHz NMR spectrometer using single pulse sequence under consistent experimental conditions: a spectral width of 15,495.86 Hz, 64K data points, a 90° flip angle, a relaxation delay of 10 seconds, an acquisition time of 2.11 seconds, and 64 scans with 8 dummy scans. The MRS data were analyzed and quantified using TOPSPIN 4.0.6 software. Spectral processing included zero-filling to 64K and applying an exponential line broadening of 0.3 Hz before Fourier transformation. Peak integration was performed using AMIX software, and the area under each peak was used for quantitative analysis after normalization to the internal standard, TSP (trimethylsilylpropanoic acid). <strong> </strong>We identified, for the first time, the profound effects of pancreatic cancer induced cachexia on visceral organ weight and metabolism that can lead to severe consequences in organ function ranging from affecting pathways involved in tissue regeneration and resolving inflammation, to altering IL-4 production in cachectic mice. These results highlight the damaging systemic changes in visceral organ metabolism that occur with cancer induced cachexia that may lead to metabolic interventions to reduce morbidity and mortality. </p> <p> </p> <p> </p>
Blood Proteins in Finding Pancreatic Cancer and Extrahepatic Biliary Tract Cancer
ClinicalTrials.gov study NCT00559598. IPD Sharing: Not stated. Countries: 0. Publications: 0.
S-1, Irinotecan, and Oxaliplatin in Locally-Advanced Pancreatic Cancer
ClinicalTrials.gov study NCT03316326. IPD Sharing: NO. Countries: 0. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.