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3,584
datasets available to search
ShareScore release 0.9.0
Dataset results
3,584 results for “Fibroblasts”
Direct conversion of normal and patient human fibroblasts into neuronal cells
GEO Series GSE69480. Homo sapiens. 6 samples. Type: Expression profiling by array.
STAT1, STAT2 and IRF9 transcription factor binding analysis in wild type mouse embryonic fibroblasts (MEF) in response to type I interferons
GEO Series GSE128107. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Gene expression profiling of xenografts and mouse embryonic fibroblasts with ectopically expressed PREX2 mutants
GEO Series GSE57311. Mus musculus; Homo sapiens. 24 samples. Type: Expression profiling by array.
Chemical reprogramming of fibroblasts into functional retinal pigment epithelium cells (scRNA-seq)
GEO Series GSE287517. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Fibroblast starvation activates ECM remodeling gene transcription and putative enhancers despite inducing quiescence [chipseq]
GEO Series GSE272507. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Effect of heterotypic interaction between breast cancer cell line MDA-MB231 and CCL-171 fibroblast
GEO Series GSE7263. Homo sapiens. 11 samples. Type: Expression profiling by array.
Human Subperitoneal Fibroblasts and Cancer Cell Interaction Creates Microenvironment Enhancing Tumor Progression and Metastasis
GEO Series GSE53059. Homo sapiens. 12 samples. Type: Expression profiling by array.
Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis [ChIP-seq]
GEO Series GSE129085. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
miRNA expression profiling divides follicular dendritic cell sarcomas into two groups, related to fibroblasts and myopericytomas or Castleman's disease
GEO Series GSE83994. Homo sapiens; synthetic construct. 58 samples. Type: Non-coding RNA profiling by array.
Gain-of-Function p53 Protein Transferred via Small Extracellular Vesicles Promotes Conversion of Fibroblasts to a Cancer-Associated Phenotype [microarray]
GEO Series GSE164248. Homo sapiens. 6 samples. Type: Expression profiling by array.
HOXA11-AS regulates NIPAL3 via hsa-miRNA-19a-3p, hsa-miR-141-3p and hsa-miR-140-5p in keloid fibroblast: stepwise bioinformatical screen for an integrated molecular network
GEO Series GSE191267. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Spatial and single-cell transcriptional profiling identifies functionally distinct human dermal fibroblast subpopulations
GEO Series GSE104225. Mus musculus. 12 samples. Type: Expression profiling by array.
Gene Expression Profile Changes due to Bleomycin-Induced DNA Damage in Human Fibroblasts in Space
To understand gene expression responses in confluent human fibroblast in microgravity conditions to bleomycin treatment. Confluent human fibroblasts AG01522 were flown to the International Space Station (ISS). After three day on ISS, the cells were treated with bleomycin at 1.0 microg/ml for 3 hours. The cells were washed and fixed with RNALater. Total RNA were isolated after the samples were returned to earth and subject to microarray analysis.
Gene expression profiling in human fibroblast after low-LET irradiation
Exposure to radiation provokes cellular responses controlled in part by gene expression networks. MicroRNAs (miRNAs) are small non-coding RNAs which mostly regulate gene expression by degrading the messages or inhibiting translation. Here we investigated changes in miRNA expression patterns after low (0.1 Gy) and high (2.0 Gy) doses of X-ray in human fibroblasts. At early (0.5 h) and late (6 and 24 h) time points irradiation caused qualitative and quantitative differences in the down-regulation of miRNA levels including miR-92b 137 660 and 656. A transient up-regulation of miRNAs was observed after 2 h post-irradiation following high doses of radiation including miR-558 and 662. MicroRNA levels were inversely correlated with targets from mRNA and proteomic profiling after 2.0 Gy of radiation. MicroRNAs miR-579 608 548-3p and 585 are noted for targeting genes involved in radioresponsive mechanisms such as cell cycle checkpoint and apoptosis. We suggest here a model in which miRNAs may act as hub regulators of specific cellular responses immediately down-regulated so as to stimulate DNA repair mechanisms followed by up-regulation involved in suppressing apoptosis for cell survival. Taken together miRNAs may mediate signaling pathways in sequential fashion in response to radiation and may serve as biodosimetric markers of radiation exposure. Overall design: The gene expression patterns in human fibroblasts after 2.0 Gy of low-LET radiation was determined at 2 and 24 hrs post-irradiation time in technical triplicates. Control non-irradiated samples were also prepared in triplicates.
Transient gene expression profile changes of confluent human fibroblast cells in spaceflight
Microgravity or an altered gravity environment from the static 1g has been shown to influence global gene expression patterns and protein levels in cultured cells or animals, but it is unclear how these changes in gene and protein expressions are related to each other or are related to other factors regulating such changes. Recent advancement in the field of molecular biology revealed that a different class of RNA, the small non-coding microRNA (miRNA), can have a broad effect on gene expression networks by mainly inhibiting the translational process. In this experiment conducted on the International Space Station, we propose to test the hypotheses that miRNA profiles will be altered in the space environment, and that cellular responses to DNA damage in space are different from those on the ground.
Fate restricted stromal fibroblasts and adipocytes demonstrate multi-modal responses to tissue injury
GEO Series GSE175650. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.
Segmental chromosomal imbalances arise at high frequency in human fibroblasts (SB_sc_1)
GEO Series GSE75093. Homo sapiens. 38 samples. Type: SNP genotyping by SNP array.
RNA-seq profiling of gene expression in mock-infected and human cytomegalovirus (HCMV)–infected human embryonic lung fibroblasts (HELF) at 72 hours post infection (two biological replicates per condit
GEO Series GSE307100. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Next Generation Sequencing Analysis of Beta-actin knockout (KO) Mouse Embryonic Fibroblast (MEFs) Transcriptomes Stimulated by Viral Mimics
GEO Series GSE130596. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq analysis of primary dermal fibroblasts of Hutchinson-Gilford progeria syndrome.
GEO Series GSE141950. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.