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5,448
datasets available to search
ShareScore release 0.9.0
Dataset results
5,448 results for “Neuron”
Use of mice defective in interferon signaling to distinguish between primary and secondary pathological pathways in a mouse model of neuronal forms of Gaucher disease
GEO Series GSE150266. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
Macrophages amplify damaged sensory neuron spontaneous activity in a human co-culture model of neuropathic pain [human]
GEO Series GSE298325. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing; Other.
Deep sequencing of somatosensory neurons reveals molecular determinants of intrinsic physiological properties
GEO Series GSE131230. Mus musculus. 26 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic Analysis of iPSC-derived Cortical Neurons Under TSA and Aβ Treatment
GEO Series GSE302545. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Single-cell chromatin conformation capture of mouse sensory neurons in visual and olfactory systems by Dip-C
GEO Series GSE121791. Mus musculus. 409 samples. Type: Other.
Severe deficiency of voltage-gated sodium channel NaV1.2 elevates neuronal excitability in adult mice
GEO Series GSE179818. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice [bulk RNA]
GEO Series GSE121099. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Molecular mechanisms for Krüppel-like factor 13 actions in hippocampal neurons [ChSP-seq]
GEO Series GSE148383. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Temporal controls over interareal cortical projection neuron fate diversity (connectID)
GEO Series GSE156080. Mus musculus. 2200 samples. Type: Expression profiling by high throughput sequencing; Other.
Kdm1a safeguards the topological boundaries of PRC2-repressed genes and prevents aging-related euchromatinization in neurons
GEO Series GSE236182. Mus musculus. 37 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
RNA-seq of DRG neurons isolated from alum vs. alum+KLH immunized mice
GEO Series GSE108428. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Analysis of miRNA expression profiles in reactivated neurons from latent PRV infection
GEO Series GSE202138. Rattus norvegicus. 9 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Transcriptomic profiling of L2HGDH-deficient and corrected human neural progenitor cells and neurons
GEO Series GSE295010. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Fibrin Hydrogels Induce Mixed Dorsal/Ventral Spinal Neuron Identities During Differentiation of Human Induced Pluripotent Stem Cells
GEO Series GSE79442. Homo sapiens. 45 samples. Type: Expression profiling by high throughput sequencing.
Histone Methyltransferase G9a in Primary Sensory Neurons Promotes Inflammatory Pain and Transcription of Trpa1 and Trpv1 via Bivalent Histone Modifications
GEO Series GSE272517. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Supplementary tables for "Differential neuropeptide modulation of premotor and motor neurons in the lobster cardiac ganglion underlies changes in patterned neuronal output"
<p>Supplementary tables for "Differential neuropeptide modulation of premotor and motor neurons in the lobster cardiac ganglion"</p>
Data from: Neuron-specific knockouts indicate the importance of network communication to Drosophila rhythmicity
<p>Animal circadian rhythms persist in constant darkness and are driven by intracellular transcription-translation feedback loops. Although these cellular oscillators communicate, isolated mammalian cellular clocks continue to tick away in darkness without intercellular communication. To investigate these issues in Drosophila, we assayed behavior as well as molecular rhythms within individual brain clock neurons while blocking communication within the ca. 150 neuron clock network. We also generated CRISPR-mediated neuron-specific circadian clock knockouts. The results point to two key clock neuron groups: loss of the clock within both regions but neither one alone has a strong behavioral phenotype in darkness; communication between these regions also contributes to circadian period determination. Under these dark conditions, the clock within one region persists without network communication. The clock within the famous PDF-expressing s-LNv neurons however was strongly dependent on network communication, likely because clock gene expression within these vulnerable sLNvs depends on neuronal firing or light</p>
Data from: Modularity induced gating and delays in neuronal networks
Neural networks, despite their highly interconnected nature, exhibit distinctly localized and gated activation. Modularity, a distinctive feature of neural networks, has been recently proposed as an important parameter determining the manner by which networks support activity propagation. Here we use an engineered biological model, consisting of engineered rat cortical neurons, to study the role of modular topology in gating the activity between cell populations. We show that pairs of connected modules support conditional propagation (transmitting stronger bursts with higher probability), long delays and propagation asymmetry. Moreover, large modular networks manifest diverse patterns of both local and global activation. Blocking inhibition decreased activity diversity and replaced it with highly consistent transmission patterns. By independently controlling modularity and disinhibition, experimentally and in a model, we pose that modular topology is an important parameter affecting activation localization and is instrumental for population-level gating by disinhibition.
Data from: Neuronal connectome of a sensory-motor circuit for visual navigation
Animals use spatial differences in environmental light levels for visual navigation; however, how light inputs are translated into coordinated motor outputs remains poorly understood. Here we reconstruct the neuronal connectome of a four-eye visual circuit in the larva of the annelid Platynereis using serial-section transmission electron microscopy. In this 71-neuron circuit, photoreceptors connect via three layers of interneurons to motorneurons, which innervate trunk muscles. By combining eye ablations with behavioral experiments, we show that the circuit compares light on either side of the body and stimulates body bending upon left-right light imbalance during visual phototaxis. We also identified an interneuron motif that enhances sensitivity to different light intensity contrasts. The Platynereis eye circuit has the hallmarks of a visual system, including spatial light detection and contrast modulation, illustrating how image-forming eyes may have evolved via intermediate stages contrasting only a light and a dark field during a simple visual task.
Data from: Changes in activity of the same thalamic neurons to repeated nociception in behaving mice
The sensory thalamus has been reported to play a key role in central pain sensory modulation and processing, but its response to repeated nociception at thalamic level is not well known. Current study investigated thalamic response to repeated nociception by recording and comparing the activity of the same thalamic neuron during the 1st and 2nd formalin injection induced nociception, with a week interval between injections, in awake and behaving mice. Behaviorally, the 2nd injection induced greater nociceptive responses than the 1st. Thalamic activity mirrored these behavioral changes with greater firing rate during the 2nd injection. Analysis of tonic and burst firing, characteristic firing pattern of thalamic neurons, revealed that tonic firing activity was potentiated while burst firing activity was not significantly changed by the 2nd injection relative to the 1st. Likewise, burst firing property changes, which has been consistently associated with different phases of nociception, were not induced by the 2nd injection. Overall, data suggest that repeated nociception potentiated responsiveness of thalamic neurons and confirmed that tonic firing transmits nociceptive signals.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.