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779 results for “CTCF”
A CRISPR-Cas9 screen identifies essential CTCF anchor sites for Estrogen Receptor-driven breast cancer cell proliferation
GEO Series GSE124667. Homo sapiens. 28 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Co-localization and cluster analysis data for paper "Dynamic regulation of CTCF stability and sub-nuclear localization in response to stress"
<p>This datasets contains all data for the co-localization and cluster analysis included in the following paper<br> "Dynamic regulation of CTCF stability and sub-nuclear localization in response to stress"</p>
ADNP modulates SINE B2-derived CTCF-binding sites during blastocyst formation in mice
<p>CTCF is crucial for chromatin structure and transcription regulation in early embryonic development.However, the</p> <p>kinetics of CTCF chromatin occupation in preimplantation embryos have remained unclear. In this study, we used</p> <p>CUT<span>&</span>RUN technology to investigate CTCF occupancy in mouse preimplantation development. Our findings revealed</p> <p>that CTCF begins binding to the genome prior to zygotic genome activation (ZGA), with a preference for</p> <p>CTCF-anchored chromatin loops. Although the majority of CTCF occupancy is consistently maintained, we</p> <p>identified a specific set of binding sites enriched in the mouse-specific short interspersed element (SINE) family B2</p> <p>that are restricted to the cleavage stages. Notably,we discovered that the neuroprotective protein ADNPcounteracts</p> <p>the stable association of CTCF at SINE B2-derived CTCF-binding sites. Knockout of <span>Adnp </span>in the zygote led to</p> <p>impaired CTCF binding signal recovery, failed deposition of H3K9me3, and transcriptional derepression of SINE B2</p> <p>during the morula-to-blastocyst transition, which further led to unfaithful cell differentiation in embryos around</p> <p>implantation. Our analysis highlights an ADNP-dependent restriction of CTCF binding during cell differentiation in</p> <p>preimplantation embryos. Furthermore, our findings shed light on the functional importance of transposable elements</p> <p>(TEs) in promoting genetic innovation and actively shaping the early embryo developmental process specific</p> <p>to mammals.</p>
A Study of CCCTC-binding Factor (CTCF) in Infantile Hemangiomas
ClinicalTrials.gov study NCT00974129. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Blood Clearance Kinetics of the Nucleosome and CTCF in Peritoneal Metastasis Colorectal Cancer.
ClinicalTrials.gov study NCT06929013. IPD Sharing: Not stated. Countries: 1. Publications: 0.
CTCF promotes RNA pol II pausing and links DNA methylation to alternative splicing [RNA-Seq]
GEO Series GSE31486. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Distinct properties and functions of CTCF revealed by a rapidly inducible degron system [PRO-Seq]
GEO Series GSE150414. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
O-GlcNAcylation of CTCF regulates 3D chromatin structure
GEO Series GSE255897. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Cohesin and CTCF do not assemble TADs in Xenopus sperm and male pronuclei
GEO Series GSE237051. Homo sapiens; Mus musculus; Xenopus laevis. 28 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
The aberrant epigenome of DNMT3B-mutated ICF1 patient iPSCs is amenable to correction, with the exception of a subset of regions with H3K4me3- and/or CTCF-based epigenetic memory (WGBS)
GEO Series GSE197924. Homo sapiens. 7 samples. Type: Methylation profiling by high throughput sequencing.
Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation II
GEO Series GSE146450. Mus musculus. 14 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
CTCF Functions as an Insulator for Somatic Genes and a Structural Regulator for Pluripotent Genes during Reprogramming [ATAC-seq]
GEO Series GSE123667. Mus musculus. 32 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
CTCF regulates hepatitis B virus cccDNA chromatin topology [RNA-seq]
GEO Series GSE249278. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
CGGBP1-dependent CTCF-binding sites restrict ectopic transcription
GEO Series GSE171990. Homo sapiens. 2 samples. Type: Other.
RNA-seq analysis comparing WT, Rad21 MO and CTCF MO zebrafish embryos at stages (2.5, 3.3, 4.5, 5.3, 10 hpf) pre and post ZGA (zygotic genome activation)
GEO Series GSE84601. Danio rerio. 45 samples. Type: Expression profiling by high throughput sequencing.
ZNF143 mediates CTCF-bound promoter-enhancer loops required for murine hematopoietic stem and progenitor cell function
GEO Series GSE144712. Mus musculus. 25 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Single-cell Multiomics Analysis Reveals CTCF as a Key Regulator of Lung Morphogenesis and Progenitor Maintenance
GEO Series GSE286982. Mus musculus. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression
GEO Series GSE138937. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
CTCF-mediated 3D chromatin predetermines the gene expression program in the male germline (RNA-Seq)
GEO Series GSE272432. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide maps of CTCF in glioblastoma
GEO Series GSE139416. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.