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319
datasets available to search
ShareScore release 0.7.1
Dataset results
319 results for “Cell biology”
DNMT3A mutations define a unique biological and prognostic subgroup associated with cytotoxic T-cells in PTCL-NOS [RNA-Seq]
GEO Series GSE204876. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
Defining heterogeneity and biological signature in human effector memory CD8+ T cells expressing different levels of IL-7 receptor alpha by high-dimensional analysis
GEO Series GSE133167. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic landscapes provide a framework of native gene expression from which to imagine new connections in cell biology
GEO Series GSE125804. Saccharomyces cerevisiae. 8 samples. Type: Expression profiling by high throughput sequencing.
The molecular landscape and biological alterations induced by PRAS40-knockout in head and neck squamous cell carcinoma.
GEO Series GSE163613. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Distinctive Biological Properties Between Mesenchymal Stem Cells Spheroids and Clumps of Mesenchymal Stem Cells/Extracellular Matrix Complexes in 3D Culture Systems.
GEO Series GSE247989. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Analysis of biological characterization and metastasis-related genes in cell lines derived from the Primary lesion and lymph node metastasis of a squamous cell carcinoma arising in the mandibular ging
GEO Series GSE54672. Homo sapiens. 2 samples. Type: Expression profiling by array.
Identification of cell signaling pathway associated miRNAs in cancer cells using a systems biological approach: potent RNAi response in cancer using novel 2’-OMe-phosphorodithioated modified siRNAs
GEO Series GSE61752. Homo sapiens. 12 samples. Type: Expression profiling by array.
Unravelling the Biological Functions of Type 1 Diabetes Associated Noncoding Single-Nucleotide Polymorphism in Human Pancreatic β Cells
GEO Series GSE166785. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Isolation of biologically active small peptide from KSHV LANA protein sequence, which induces CHD4 degradation to promote cell differentiation and inhibits leukemic cell growth (RNA-seq)
GEO Series GSE228553. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Palmitate-induced inhibition of C2C12 insulin pathway modifies the release of exosomes and their biological actions on muscle cells
GEO Series GSE52048. Mus musculus. 7 samples. Type: Expression profiling by array.
The physicochemistry of capped nanosilver predicts it biological activity in brain endothelial (RBEC4) cells
GEO Series GSE47543. Rattus norvegicus. 24 samples. Type: Expression profiling by array.
Human mesenchymal stem cells at 24 hours and 0.5% O2, gene expression and exon array, three independent biological replicates
GEO Series GSE32006. Homo sapiens. 12 samples. Type: Expression profiling by array.
Understanding the biological processes of clear cell renal carcinoma carcinogenesis: an integrative multi-omics approach.
GEO Series GSE269180. Homo sapiens. 121 samples. Type: Methylation profiling by genome tiling array.
Biological characteristics of gene expression features in pancreatic cancer cell induced by proton and x-ray irradiation IV
GEO Series GSE107443. Homo sapiens. 8 samples. Type: Expression profiling by array.
New functional signatures for understanding melanoma biology from tumor cell lineage-specific analysis [single channel experiments]
GEO Series GSE67635. Homo sapiens. 21 samples. Type: Expression profiling by array.
Dataset related to article "Post-biopsy cell-free DNA from blood: an open window on primary prostate cancer genetics and biology"
<p>This record contains data related to article "Post-biopsy cell-free DNA from blood: an open window on primary prostate cancer genetics and biology".</p> <p>Circulating cell-free DNA (ccfDNA), released from normal and cancerous cells, is a promising biomarker for cancer detection as in neoplastic patients it is enriched in tumor-derived DNA (ctDNA). ctDNA contains cancer-specific mutations and epigenetic modifications, which can have diagnostic/prognostic value. However, in primary tumors, and in particular in localized prostate cancer (PCa), the fraction of ctDNA is very low and conventional strategies to study ccfDNA are unsuccessful. Here we demonstrate that prostate biopsy, by causing multiple injuries to the organ, leads to a significant increase in plasma concentration of ccfDNA (P<0.0024) in primary PCa patients. By calculating the minor allele fraction at patient-specific somatic mutations pre- and post-biopsy, we show that ctDNA is significantly enriched (from 3.9 to 164 fold) after biopsy, representing a transient “molecular window” to access and analyze ctDNA. Moreover, we show that newly released ccfDNA contains a larger fraction of di-, tri- and multi-nucleosome associated DNA fragments. This feature could be exploited to further enrich prostate-derived ccfDNA and to analyze epigenetic markers. Our data represent a proof-of-concept that liquid tumor profiling from peripheral blood performed just after the biopsy procedure can open a “valuable molecular metastatic window” giving access to the tumor genetic asset, thus providing an opportunity for early cancer detection and individual genomic profiling in the view of PCa precision medicine.</p>
Isolation of biologically active small peptide from KSHV LANA protein sequence, which induces CHD4 degradation to promote cell differentiation and inhibits leukemic cell growth (SLAM-seq)
GEO Series GSE228656. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing; Other.
Immunosubtyping of breast cancer reveals distinct myeloid cell biology and immunotherapy resistance mechanisms
GEO Series GSE104765. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.
Biological characteristics of gene expression features in pancreatic cancer cell induced by proton and x-ray irradiation II
GEO Series GSE107441. Homo sapiens. 9 samples. Type: Expression profiling by array.
Effects of (E)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one (BF8) on E. coli RP437 persister cells (two biological replicates)
GEO Series GSE44273. Escherichia coli. 4 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.