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622
datasets available to search
ShareScore release 0.9.0
Dataset results
622 results for “Genomic integrity”
Integrative genomic profiling of human prostate cancer
GEO Series GSE21032. Homo sapiens. 743 samples. Type: Expression profiling by array; Genome variation profiling by genome tiling array; Non-coding RNA profiling by array.
A p53-CCF circuit integrates genome integrity with senescence phenotypes [WGS 1]
GEO Series GSE259296. Homo sapiens. 14 samples. Type: Other.
THE INTEGRATIVE GENOMIC AND FUNCTIONAL IMMUNOLOGICAL ANALYSES OF COLORECTAL CANCER INITIATING CELLS TO MODULATE STEMNESS PROPERTIES AND THE SUSCEPTIBILIY TO IMMUNE RESPONSES [miRNA]
GEO Series GSE287585. Homo sapiens. 23 samples. Type: Non-coding RNA profiling by array.
Integrative genomics outlines a biphasic glucose response and a ChREBP-RORγ axis regulating proliferation in β-cells
GEO Series GSE81628. Rattus norvegicus. 54 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
DNA methylation maintains integrity of higher order genome architecture (Hi-C)
GEO Series GSE158007. Homo sapiens. 6 samples. Type: Other.
An integrated toolkit for human microglia functional genomics
GEO Series GSE244653. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Integrative genomics sheds light on the immunogenetics of tuberculosis in cattle
GEO Series GSE255724. Bos taurus. 123 samples. Type: Expression profiling by high throughput sequencing.
An integrated peach genome structural variation map uncovers genes associated with fruit traits
<p>The VCF files generated from 336 peach accessions, including SVs (>50bp), SNPs and indels (<50bp).</p>
Data from: pLARmEB: integration of least angle regression with empirical Bayes for multilocus genome-wide association studies
Multilocus genome-wide association studies (GWAS) have become the state-of-the-art procedure to identify quantitative trait nucleotides (QTNs) associated with complex traits. However, implementation of multilocus model in GWAS is still difficult. In this study, we integrated least angle regression with empirical Bayes to perform multilocus GWAS under polygenic background control. We used an algorithm of model transformation that whitened the covariance matrix of the polygenic matrix K and environmental noise. Markers on one chromosome were included simultaneously in a multilocus model and least angle regression was used to select the most potentially associated single-nucleotide polymorphisms (SNPs), whereas the markers on the other chromosomes were used to calculate kinship matrix as polygenic background control. The selected SNPs in multilocus model were further detected for their association with the trait by empirical Bayes and likelihood ratio test. We herein refer to this method as the pLARmEB (polygenic-background-control-based least angle regression plus empirical Bayes). Results from simulation studies showed that pLARmEB was more powerful in QTN detection and more accurate in QTN effect estimation, had less false positive rate and required less computing time than Bayesian hierarchical generalized linear model, efficient mixed model association (EMMA) and least angle regression plus empirical Bayes. pLARmEB, multilocus random-SNP-effect mixed linear model and fast multilocus random-SNP-effect EMMA methods had almost equal power of QTN detection in simulation experiments. However, only pLARmEB identified 48 previously reported genes for 7 flowering time-related traits in Arabidopsis thaliana.
ROAR-DIGAP: A Widely Inclusive, Largely Virtual Pilot Trial Utilizing DIGAP (Deep Integrated Genomics Analysis Platform) To Personalize Treatments
ClinicalTrials.gov study NCT06429059. IPD Sharing: NO. Countries: 1. Publications: 0.
Molecular Testing of Cancer by Integrated Genomic, Transcriptomic, and Proteomic Analysis
ClinicalTrials.gov study NCT02213822. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Integrated Genomics in Oncogene-driven NSCLC With Acquired Resistance
ClinicalTrials.gov study NCT07122882. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Integrated Genomic Prostate Score With MRI Targeted Prostate Biopsies
ClinicalTrials.gov study NCT04541030. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Phase II Study of Avelumab in Metastatic Gastronetro-pancreatic （GEP） Neuroendocrine Carcinoma （NEC, WHO Grade 3） as Second-line Treatment After Failing to Etoposide+Cisplatin: Integration of Genomic
ClinicalTrials.gov study NCT03147404. IPD Sharing: Not stated. Countries: 1. Publications: 0.
An Integrative Genomic Approach to Solve tHe Puzzle of sevERe earLy-Onset COPD
ClinicalTrials.gov study NCT04263961. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study of Pembrolizumab in Metastatic Biliary Tract Cancer as Second-line Treatment After Failing to at Least One Cytotoxic Chemotherapy Regimen: Integration of Genomic Analysis to Identify Predictive
ClinicalTrials.gov study NCT03110328. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Unified platforM for a Better integRal Evaluation of MyeLodyspLastic Syndromes in SpAin-Strategy for Unraveling Personalized genoMic Medicine in Public heAlth System (UMBRELLA-SUMMA)
ClinicalTrials.gov study NCT06379945. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Integrating Molecular, Genomic, Morphology and Environmental Features to Improve Precision Diagnosis and Treatment in Interstitial Lung Diseases (PRECISION-ILD)
ClinicalTrials.gov study NCT05998512. IPD Sharing: NO. Countries: 1. Publications: 0.
"A Privacy-protecting Environment for Child Transplants Health Related and Genomic Data Integration in the European Reference Network"
ClinicalTrials.gov study NCT07194057. IPD Sharing: NO. Countries: 3. Publications: 0.
Genome wide analysis of human iPS cell lines generated with non-integrative plasmids and knock-down of P53 gene
GEO Series GSE48665. Homo sapiens. 8 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.